Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912262032> ?p ?o ?g. }
- W2912262032 endingPage "548" @default.
- W2912262032 startingPage "513" @default.
- W2912262032 abstract "Abstract Edema, also termed oedema, is a generalized medical condition associated with an abnormal aggregation of fluid in a tissue matrix. In the intestine, excessive edema can lead to serious health complications associated with reduced motility. A $7.5%$ solution of hypertonic saline (HS) has been hypothesized as an effective means to reduce the effects of edema following surgery or injury. However, detailed clinical edema experiments can be difficult to implement, or costly, in practice. In this manuscript we introduce an implicit in time discontinuous Galerkin method with novel adaptations for modeling edema in the 3D layered physiology of the intestine. The model improves over early work via inclusion of the tissue intrinsic storage coefficient, and the effects of Starling overestimation for high venous pressures. Validation against a recent clinical experiment in HS resuscitation of acute edema is presented; the results support the clinical hypothesis that 7.5% HS solution may be effective in the resuscitation of acute edema formation. New results include an improved view into the effects of resuscitation on the hydrostatic pressure profile of edematous rats, effects on lumenal volume attenuation, relative fluid gain and an estimation of the impacts of both acute edema and resuscitation on intestinal motility." @default.
- W2912262032 created "2019-02-21" @default.
- W2912262032 creator A5011949071 @default.
- W2912262032 creator A5011952233 @default.
- W2912262032 creator A5046673531 @default.
- W2912262032 date "2019-02-05" @default.
- W2912262032 modified "2023-09-27" @default.
- W2912262032 title "An implicit discontinuous Galerkin method for modeling acute edema and resuscitation in the small intestine" @default.
- W2912262032 cites W1515914868 @default.
- W2912262032 cites W1516132534 @default.
- W2912262032 cites W1569090332 @default.
- W2912262032 cites W1818227613 @default.
- W2912262032 cites W1853307226 @default.
- W2912262032 cites W1900765734 @default.
- W2912262032 cites W1970009422 @default.
- W2912262032 cites W1970531142 @default.
- W2912262032 cites W1975425841 @default.
- W2912262032 cites W1976191047 @default.
- W2912262032 cites W1976945804 @default.
- W2912262032 cites W1977727715 @default.
- W2912262032 cites W1978180994 @default.
- W2912262032 cites W1981844992 @default.
- W2912262032 cites W1985166491 @default.
- W2912262032 cites W1986093704 @default.
- W2912262032 cites W1988597835 @default.
- W2912262032 cites W1995421493 @default.
- W2912262032 cites W2005681997 @default.
- W2912262032 cites W2007505252 @default.
- W2912262032 cites W2008787883 @default.
- W2912262032 cites W2017048267 @default.
- W2912262032 cites W2023271522 @default.
- W2912262032 cites W2025754052 @default.
- W2912262032 cites W2027166083 @default.
- W2912262032 cites W2039136672 @default.
- W2912262032 cites W2044863064 @default.
- W2912262032 cites W2054122357 @default.
- W2912262032 cites W2055072688 @default.
- W2912262032 cites W2060471433 @default.
- W2912262032 cites W2065538879 @default.
- W2912262032 cites W2066129465 @default.
- W2912262032 cites W2067817461 @default.
- W2912262032 cites W2068139426 @default.
- W2912262032 cites W2068326901 @default.
- W2912262032 cites W2069194477 @default.
- W2912262032 cites W2072045671 @default.
- W2912262032 cites W2073105285 @default.
- W2912262032 cites W2075954740 @default.
- W2912262032 cites W2084822006 @default.
- W2912262032 cites W2086509084 @default.
- W2912262032 cites W2087550514 @default.
- W2912262032 cites W2087706937 @default.
- W2912262032 cites W2089366649 @default.
- W2912262032 cites W2089900628 @default.
- W2912262032 cites W2099590846 @default.
- W2912262032 cites W2109531240 @default.
- W2912262032 cites W2112311198 @default.
- W2912262032 cites W2115352852 @default.
- W2912262032 cites W2135651821 @default.
- W2912262032 cites W2139122457 @default.
- W2912262032 cites W2142332363 @default.
- W2912262032 cites W2142517925 @default.
- W2912262032 cites W2147734293 @default.
- W2912262032 cites W2150755107 @default.
- W2912262032 cites W2156095889 @default.
- W2912262032 cites W2158030787 @default.
- W2912262032 cites W2159133961 @default.
- W2912262032 cites W2165124404 @default.
- W2912262032 cites W2166338864 @default.
- W2912262032 cites W2167664493 @default.
- W2912262032 cites W2172023922 @default.
- W2912262032 cites W2175556970 @default.
- W2912262032 cites W2175935254 @default.
- W2912262032 cites W2177224260 @default.
- W2912262032 cites W2225553573 @default.
- W2912262032 cites W2268978984 @default.
- W2912262032 cites W2273477358 @default.
- W2912262032 cites W2276528930 @default.
- W2912262032 cites W2302530002 @default.
- W2912262032 cites W2340813917 @default.
- W2912262032 cites W2401112454 @default.
- W2912262032 cites W2572055818 @default.
- W2912262032 cites W2964046760 @default.
- W2912262032 cites W4242957860 @default.
- W2912262032 cites W4244104762 @default.
- W2912262032 cites W93674340 @default.
- W2912262032 doi "https://doi.org/10.1093/imammb/dqz001" @default.
- W2912262032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30722029" @default.
- W2912262032 hasPublicationYear "2019" @default.
- W2912262032 type Work @default.
- W2912262032 sameAs 2912262032 @default.
- W2912262032 citedByCount "6" @default.
- W2912262032 countsByYear W29122620322019 @default.
- W2912262032 countsByYear W29122620322021 @default.
- W2912262032 countsByYear W29122620322022 @default.
- W2912262032 crossrefType "journal-article" @default.
- W2912262032 hasAuthorship W2912262032A5011949071 @default.
- W2912262032 hasAuthorship W2912262032A5011952233 @default.
- W2912262032 hasAuthorship W2912262032A5046673531 @default.