FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912264066> ?p ?o ?g. }

• W2912264066 endingPage "793" @default.
• W2912264066 startingPage "793" @default.
• W2912264066 abstract "Urothelial carcinoma of the bladder (UCB) and upper tracts (UTUC) is often regarded as one entity and is managed generally with similar principles. While neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC) is an established standard of care in UCB, strong evidence for a similar approach is lacking in UTUC. The longest survival is seen in patients with complete response (pT0) on pathological examination of the RC specimen, but impact of delayed RC in nonresponders may be detrimental. The rate of pT0 following NAC in UTUC is considerably lower than that in UCB due to differences in access and instrumentation. Molecular markers have been evaluated to try to predict response to chemotherapy to reduce unnecessary treatment and expedite different treatment for nonresponders. A variety of potential biomarkers have been evaluated to predict response to cisplatin based chemotherapy including DNA repair genes (ATM, RB1, FANCC, ERCC2, BRCA1, and ERCC1), regulators of apoptosis (survivin, Bcl-xL, and emmprin), receptor tyrosine kinases (EGFR and erbB2), genes involved in cellular efflux (MDR1 and CTR1), in addition to molecular subtypes (Basal, luminal, and p53-like). The current state of the literature on the prediction of response to NAC based on the presence of these biomarkers is discussed in this review." @default.
• W2912264066 created "2019-02-21" @default.
• W2912264066 creator A5009833645 @default.
• W2912264066 creator A5020506299 @default.
• W2912264066 creator A5030962772 @default.
• W2912264066 creator A5041923034 @default.
• W2912264066 date "2019-02-13" @default.
• W2912264066 modified "2023-09-25" @default.
• W2912264066 title "Molecular Predictors of Complete Response Following Neoadjuvant Chemotherapy in Urothelial Carcinoma of the Bladder and Upper Tracts" @default.
• W2912264066 cites W1527068138 @default.
• W2912264066 cites W1527366898 @default.
• W2912264066 cites W1550300650 @default.
• W2912264066 cites W1558385747 @default.
• W2912264066 cites W1576738591 @default.
• W2912264066 cites W1595765532 @default.
• W2912264066 cites W1711618159 @default.
• W2912264066 cites W1771287927 @default.
• W2912264066 cites W1828448189 @default.
• W2912264066 cites W185195656 @default.
• W2912264066 cites W1871279193 @default.
• W2912264066 cites W1893588230 @default.
• W2912264066 cites W1903272704 @default.
• W2912264066 cites W1912751632 @default.
• W2912264066 cites W1942258069 @default.
• W2912264066 cites W1966998359 @default.
• W2912264066 cites W1975918912 @default.
• W2912264066 cites W1980525903 @default.
• W2912264066 cites W1982703074 @default.
• W2912264066 cites W1989141974 @default.
• W2912264066 cites W2006283915 @default.
• W2912264066 cites W2012852529 @default.
• W2912264066 cites W2020945203 @default.
• W2912264066 cites W2032471331 @default.
• W2912264066 cites W2033511033 @default.
• W2912264066 cites W2033525264 @default.
• W2912264066 cites W2033775272 @default.
• W2912264066 cites W2035062922 @default.
• W2912264066 cites W2036310262 @default.
• W2912264066 cites W2036953628 @default.
• W2912264066 cites W2059994274 @default.
• W2912264066 cites W2068523052 @default.
• W2912264066 cites W2073804272 @default.
• W2912264066 cites W2074066249 @default.
• W2912264066 cites W2078878344 @default.
• W2912264066 cites W2081496297 @default.
• W2912264066 cites W2098028863 @default.
• W2912264066 cites W2101562875 @default.
• W2912264066 cites W2103192876 @default.
• W2912264066 cites W2103257412 @default.
• W2912264066 cites W2103561213 @default.
• W2912264066 cites W2103725052 @default.
• W2912264066 cites W2105631098 @default.
• W2912264066 cites W2107575831 @default.
• W2912264066 cites W2113156769 @default.
• W2912264066 cites W2117692326 @default.
• W2912264066 cites W2124614719 @default.
• W2912264066 cites W2131178190 @default.
• W2912264066 cites W2132219433 @default.
• W2912264066 cites W2146331926 @default.
• W2912264066 cites W2147180151 @default.
• W2912264066 cites W2148132746 @default.
• W2912264066 cites W2148684437 @default.
• W2912264066 cites W2150048195 @default.
• W2912264066 cites W2152418443 @default.
• W2912264066 cites W2153157914 @default.
• W2912264066 cites W2154889267 @default.
• W2912264066 cites W2158982666 @default.
• W2912264066 cites W2160107406 @default.
• W2912264066 cites W2164791945 @default.
• W2912264066 cites W2166453367 @default.
• W2912264066 cites W2168598885 @default.
• W2912264066 cites W2171883057 @default.
• W2912264066 cites W2177584245 @default.
• W2912264066 cites W2199105679 @default.
• W2912264066 cites W2202440845 @default.
• W2912264066 cites W2265447285 @default.
• W2912264066 cites W2275187454 @default.
• W2912264066 cites W2301782847 @default.
• W2912264066 cites W2332342311 @default.
• W2912264066 cites W2432541865 @default.
• W2912264066 cites W2468517428 @default.
• W2912264066 cites W2499666204 @default.
• W2912264066 cites W2552490149 @default.
• W2912264066 cites W2589185576 @default.
• W2912264066 cites W2604535399 @default.
• W2912264066 cites W2619249519 @default.
• W2912264066 cites W2619733974 @default.
• W2912264066 cites W2738951134 @default.
• W2912264066 cites W2781525129 @default.
• W2912264066 cites W2781574428 @default.
• W2912264066 cites W2795000153 @default.
• W2912264066 cites W284827844 @default.
• W2912264066 cites W2888969259 @default.
• W2912264066 cites W2895579856 @default.
• W2912264066 cites W2904555583 @default.
• W2912264066 cites W4299398734 @default.
• W2912264066 cites W2170872314 @default.
• W2912264066 cites W2462812928 @default.

• next