FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912264218> ?p ?o ?g. }

• W2912264218 endingPage "431" @default.
• W2912264218 startingPage "425" @default.
• W2912264218 abstract "Background Nonvalvular atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with the prothrombotic state. Circulating microparticles (cMPs) are membrane vesicles that are shed from many cell types in response to cell activation and cell apoptosis. Several studies reported that cMPs may play a role in the hypercoagulable state that can be observed in patients with AF. The aim of this study was to determine the levels of total cMPs and characterize their cellular origins in AF patients. Methods Atotal of 66 AF patients and 33 healthy controls were enrolled. This study investigated total cMP levels and their cellular origin in AF patients using polychromatic flow cytometry. Results AF patients had significantly higher levels of total cMPs (median 36.38, interquartile range [IQR] 21.16‐68.50 × 10 5 counts/mL vs median 15.21, IQR 9.91‐30.86 × 10 5 counts/mL; P = 0.004), platelet‐derived MPs (PMPs) (median 10.61, IQR 6.55‐18.04 × 10 5 counts/mL vs median 7.83, IQR 4.44‐10.26 × 10/mL; P = 0.009), and endothelial‐derived MPs (EMPs CD31+ CD41−) (median 2.94, IQR 1.78‐0.60 × 10 5 counts/mL vs median 1.16, IQR 0.71‐2.30 × 10 5 counts/mL; P = 0.001) than healthy controls after adjusting for potential confounders. Phosphatidylserine positive MP (PS + MP) levels were similar compared between AF patients and healthy controls. Conclusion The results of this study revealed a marked increase in total cMP levels, and evidence of elevated endothelial damage and platelet activation, as demonstrated by increased PMP and EMP levels, in AF patients. Additional study is needed to further elucidate the role of cMPs (PMPs and EMPs) in the pathophysiology of and the complications associated with AF." @default.
• W2912264218 created "2019-02-21" @default.
• W2912264218 creator A5019181956 @default.
• W2912264218 creator A5039568106 @default.
• W2912264218 creator A5040922120 @default.
• W2912264218 creator A5047677747 @default.
• W2912264218 creator A5053032453 @default.
• W2912264218 creator A5057681010 @default.
• W2912264218 creator A5069679265 @default.
• W2912264218 creator A5075588407 @default.
• W2912264218 date "2019-02-20" @default.
• W2912264218 modified "2023-09-26" @default.
• W2912264218 title "Altered profile of circulating microparticles in nonvalvular atrial fibrillation" @default.
• W2912264218 cites W1540597915 @default.
• W2912264218 cites W1966629336 @default.
• W2912264218 cites W1972070926 @default.
• W2912264218 cites W1974001859 @default.
• W2912264218 cites W1974784056 @default.
• W2912264218 cites W1988665495 @default.
• W2912264218 cites W1989593519 @default.
• W2912264218 cites W2000667628 @default.
• W2912264218 cites W2010498435 @default.
• W2912264218 cites W2015898716 @default.
• W2912264218 cites W2017269547 @default.
• W2912264218 cites W2022779333 @default.
• W2912264218 cites W2024473555 @default.
• W2912264218 cites W2049586125 @default.
• W2912264218 cites W2058690749 @default.
• W2912264218 cites W2065408869 @default.
• W2912264218 cites W2070649020 @default.
• W2912264218 cites W2071881499 @default.
• W2912264218 cites W2075207093 @default.
• W2912264218 cites W2078573963 @default.
• W2912264218 cites W2089853340 @default.
• W2912264218 cites W2107102370 @default.
• W2912264218 cites W2109147571 @default.
• W2912264218 cites W2124480950 @default.
• W2912264218 cites W2156887090 @default.
• W2912264218 cites W2158846625 @default.
• W2912264218 cites W2161283927 @default.
• W2912264218 cites W2163431279 @default.
• W2912264218 cites W2165447676 @default.
• W2912264218 cites W2170226666 @default.
• W2912264218 cites W2175366036 @default.
• W2912264218 cites W2333672259 @default.
• W2912264218 cites W2369150255 @default.
• W2912264218 cites W2462468412 @default.
• W2912264218 cites W2519908769 @default.
• W2912264218 cites W2527232729 @default.
• W2912264218 cites W2558092474 @default.
• W2912264218 cites W2588674545 @default.
• W2912264218 cites W2620594759 @default.
• W2912264218 cites W2735790728 @default.
• W2912264218 cites W2790707599 @default.
• W2912264218 cites W2903401351 @default.
• W2912264218 cites W4297900932 @default.
• W2912264218 doi "https://doi.org/10.1002/clc.23158" @default.
• W2912264218 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6712324" @default.
• W2912264218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30680757" @default.
• W2912264218 hasPublicationYear "2019" @default.
• W2912264218 type Work @default.
• W2912264218 sameAs 2912264218 @default.
• W2912264218 citedByCount "16" @default.
• W2912264218 countsByYear W29122642182019 @default.
• W2912264218 countsByYear W29122642182020 @default.
• W2912264218 countsByYear W29122642182021 @default.
• W2912264218 countsByYear W29122642182022 @default.
• W2912264218 crossrefType "journal-article" @default.
• W2912264218 hasAuthorship W2912264218A5019181956 @default.
• W2912264218 hasAuthorship W2912264218A5039568106 @default.
• W2912264218 hasAuthorship W2912264218A5040922120 @default.
• W2912264218 hasAuthorship W2912264218A5047677747 @default.
• W2912264218 hasAuthorship W2912264218A5053032453 @default.
• W2912264218 hasAuthorship W2912264218A5057681010 @default.
• W2912264218 hasAuthorship W2912264218A5069679265 @default.
• W2912264218 hasAuthorship W2912264218A5075588407 @default.
• W2912264218 hasBestOaLocation W29122642181 @default.
• W2912264218 hasConcept C119060515 @default.
• W2912264218 hasConcept C126322002 @default.
• W2912264218 hasConcept C164705383 @default.
• W2912264218 hasConcept C203014093 @default.
• W2912264218 hasConcept C2777292125 @default.
• W2912264218 hasConcept C2778914503 @default.
• W2912264218 hasConcept C2779161974 @default.
• W2912264218 hasConcept C3018972837 @default.
• W2912264218 hasConcept C553184892 @default.
• W2912264218 hasConcept C71924100 @default.
• W2912264218 hasConcept C89560881 @default.
• W2912264218 hasConcept C90924648 @default.
• W2912264218 hasConceptScore W2912264218C119060515 @default.
• W2912264218 hasConceptScore W2912264218C126322002 @default.
• W2912264218 hasConceptScore W2912264218C164705383 @default.
• W2912264218 hasConceptScore W2912264218C203014093 @default.
• W2912264218 hasConceptScore W2912264218C2777292125 @default.
• W2912264218 hasConceptScore W2912264218C2778914503 @default.
• W2912264218 hasConceptScore W2912264218C2779161974 @default.
• W2912264218 hasConceptScore W2912264218C3018972837 @default.
• W2912264218 hasConceptScore W2912264218C553184892 @default.

• next