FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912266965> ?p ?o ?g. }

• W2912266965 abstract "Abstract Graded Sonic Hedgehog (Shh) signaling emanating from notochord and floorplate patterns the early neural tube. Soon thereafter, Shh signaling strength within the ventricular zone becomes dis-contiguous and discontinuous along the ventral to dorsal axis suggesting a distribution of Shh that cannot be achieved by diffusion alone. Here we discover that sequential activation of Shh expression by ventricular zone derivatives is critical for counteracting a precocious exhaustion of the Olig2 precursor cell population of the pMN domain at the end of motor neuron genesis and during the subsequent phase of ventral oligodendrocyte precursor production. Selective expression of Shh by motor neurons of the lateral motor column at the beginning of oligodendrogenesis ensures a more yielding pMN domain at limb levels compared to thoracic levels. Thus, patterned expression of Shh by ventricular zone derivatives including earlier born neurons contributes to the scaling of the spinal cord along the anterior – posterior axis by regulating the activity of a select ventricular zone precursor domain at later stages of development." @default.
• W2912266965 created "2019-02-21" @default.
• W2912266965 creator A5057734444 @default.
• W2912266965 creator A5082135835 @default.
• W2912266965 creator A5088803552 @default.
• W2912266965 date "2019-01-30" @default.
• W2912266965 modified "2023-09-26" @default.
• W2912266965 title "Multiple sources of Shh are critical for the generation and scaling of ventral spinal cord oligodendrocyte precursor populations" @default.
• W2912266965 cites W1551739170 @default.
• W2912266965 cites W1975129643 @default.
• W2912266965 cites W1975203903 @default.
• W2912266965 cites W1976947622 @default.
• W2912266965 cites W1978772056 @default.
• W2912266965 cites W1999556680 @default.
• W2912266965 cites W2002457562 @default.
• W2912266965 cites W2017116537 @default.
• W2912266965 cites W2017848407 @default.
• W2912266965 cites W2025703347 @default.
• W2912266965 cites W2032251097 @default.
• W2912266965 cites W2036828218 @default.
• W2912266965 cites W2054196675 @default.
• W2912266965 cites W2058903813 @default.
• W2912266965 cites W2063218127 @default.
• W2912266965 cites W2067901071 @default.
• W2912266965 cites W2075307249 @default.
• W2912266965 cites W2075994912 @default.
• W2912266965 cites W2079385876 @default.
• W2912266965 cites W2081235375 @default.
• W2912266965 cites W2082807347 @default.
• W2912266965 cites W2083249373 @default.
• W2912266965 cites W2090612180 @default.
• W2912266965 cites W2090817549 @default.
• W2912266965 cites W2091728674 @default.
• W2912266965 cites W2096775905 @default.
• W2912266965 cites W2114059335 @default.
• W2912266965 cites W2125883247 @default.
• W2912266965 cites W2134084812 @default.
• W2912266965 cites W2137244527 @default.
• W2912266965 cites W2142801207 @default.
• W2912266965 cites W2156375169 @default.
• W2912266965 cites W2157103346 @default.
• W2912266965 cites W2164942167 @default.
• W2912266965 cites W2172781484 @default.
• W2912266965 cites W2181488721 @default.
• W2912266965 cites W2336245951 @default.
• W2912266965 cites W2518593643 @default.
• W2912266965 cites W2558603048 @default.
• W2912266965 cites W2605787143 @default.
• W2912266965 cites W2766471703 @default.
• W2912266965 cites W2795079092 @default.
• W2912266965 cites W2897473364 @default.
• W2912266965 cites W2897489750 @default.
• W2912266965 cites W3099632324 @default.
• W2912266965 cites W4248042899 @default.
• W2912266965 doi "https://doi.org/10.1101/534750" @default.
• W2912266965 hasPublicationYear "2019" @default.
• W2912266965 type Work @default.
• W2912266965 sameAs 2912266965 @default.
• W2912266965 citedByCount "1" @default.
• W2912266965 countsByYear W29122669652020 @default.
• W2912266965 crossrefType "posted-content" @default.
• W2912266965 hasAuthorship W2912266965A5057734444 @default.
• W2912266965 hasAuthorship W2912266965A5082135835 @default.
• W2912266965 hasAuthorship W2912266965A5088803552 @default.
• W2912266965 hasBestOaLocation W29122669651 @default.
• W2912266965 hasConcept C105702510 @default.
• W2912266965 hasConcept C124964019 @default.
• W2912266965 hasConcept C1491633281 @default.
• W2912266965 hasConcept C169760540 @default.
• W2912266965 hasConcept C185592680 @default.
• W2912266965 hasConcept C196843134 @default.
• W2912266965 hasConcept C2776133846 @default.
• W2912266965 hasConcept C2776637008 @default.
• W2912266965 hasConcept C2776985911 @default.
• W2912266965 hasConcept C2778609137 @default.
• W2912266965 hasConcept C2779055221 @default.
• W2912266965 hasConcept C2780594696 @default.
• W2912266965 hasConcept C2780775167 @default.
• W2912266965 hasConcept C2908647359 @default.
• W2912266965 hasConcept C529278444 @default.
• W2912266965 hasConcept C55493867 @default.
• W2912266965 hasConcept C62478195 @default.
• W2912266965 hasConcept C71924100 @default.
• W2912266965 hasConcept C78577261 @default.
• W2912266965 hasConcept C86803240 @default.
• W2912266965 hasConcept C87073359 @default.
• W2912266965 hasConcept C95444343 @default.
• W2912266965 hasConcept C99454951 @default.
• W2912266965 hasConceptScore W2912266965C105702510 @default.
• W2912266965 hasConceptScore W2912266965C124964019 @default.
• W2912266965 hasConceptScore W2912266965C1491633281 @default.
• W2912266965 hasConceptScore W2912266965C169760540 @default.
• W2912266965 hasConceptScore W2912266965C185592680 @default.
• W2912266965 hasConceptScore W2912266965C196843134 @default.
• W2912266965 hasConceptScore W2912266965C2776133846 @default.
• W2912266965 hasConceptScore W2912266965C2776637008 @default.
• W2912266965 hasConceptScore W2912266965C2776985911 @default.
• W2912266965 hasConceptScore W2912266965C2778609137 @default.
• W2912266965 hasConceptScore W2912266965C2779055221 @default.
• W2912266965 hasConceptScore W2912266965C2780594696 @default.

• next