Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912269398> ?p ?o ?g. }
- W2912269398 endingPage "362" @default.
- W2912269398 startingPage "357" @default.
- W2912269398 abstract "Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine- induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission and neuroadaptation, induced by exposure to recreational drugs such as morphine and methamphetamine. In this study, we investigated the effects of limonene on the psychological dependence induced by drug abuse. The development of sensitization, dopamine receptor supersensitivity, and conditioned place preferences in rats was measured following administration of limonene (10 or 20 mg/kg) and methamphetamine (1 mg/kg) for 4 days. Limonene inhibits methamphetamine- induced sensitization to locomotor activity. Expression of dopamine receptor supersensitivity induced by apomorphine, a dopamine receptor agonist, was significantly reduced in limonenepretreated rats. However, there was no significant difference in methamphetamine-induced conditioned place preferences between the limonene and control groups. These results suggest that limonene may ameliorate drug addiction-related behaviors by regulating postsynaptic dopamine receptor supersensitivity." @default.
- W2912269398 created "2019-02-21" @default.
- W2912269398 creator A5007610160 @default.
- W2912269398 creator A5044964332 @default.
- W2912269398 creator A5050499399 @default.
- W2912269398 creator A5088567252 @default.
- W2912269398 creator A5090177102 @default.
- W2912269398 date "2019-07-01" @default.
- W2912269398 modified "2023-10-16" @default.
- W2912269398 title "Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity" @default.
- W2912269398 cites W1943803076 @default.
- W2912269398 cites W1985993814 @default.
- W2912269398 cites W1986052176 @default.
- W2912269398 cites W1986674466 @default.
- W2912269398 cites W1987604732 @default.
- W2912269398 cites W1991672625 @default.
- W2912269398 cites W1992974038 @default.
- W2912269398 cites W1994855352 @default.
- W2912269398 cites W2005101125 @default.
- W2912269398 cites W2008623783 @default.
- W2912269398 cites W2008762508 @default.
- W2912269398 cites W2010333198 @default.
- W2912269398 cites W2011272115 @default.
- W2912269398 cites W2021995140 @default.
- W2912269398 cites W2024878737 @default.
- W2912269398 cites W2026292238 @default.
- W2912269398 cites W2026610597 @default.
- W2912269398 cites W2031647610 @default.
- W2912269398 cites W2035552656 @default.
- W2912269398 cites W2036747602 @default.
- W2912269398 cites W2039323107 @default.
- W2912269398 cites W2042210108 @default.
- W2912269398 cites W2054803538 @default.
- W2912269398 cites W2054831086 @default.
- W2912269398 cites W2056117721 @default.
- W2912269398 cites W2060711411 @default.
- W2912269398 cites W2065872207 @default.
- W2912269398 cites W2066596282 @default.
- W2912269398 cites W2069053550 @default.
- W2912269398 cites W2079275626 @default.
- W2912269398 cites W2087677370 @default.
- W2912269398 cites W2087928825 @default.
- W2912269398 cites W2090887496 @default.
- W2912269398 cites W2094443687 @default.
- W2912269398 cites W2105276733 @default.
- W2912269398 cites W2112214333 @default.
- W2912269398 cites W2126401900 @default.
- W2912269398 cites W2131457953 @default.
- W2912269398 cites W2164388519 @default.
- W2912269398 cites W2166417233 @default.
- W2912269398 cites W2190606247 @default.
- W2912269398 cites W2410974267 @default.
- W2912269398 cites W4319293053 @default.
- W2912269398 cites W51778931 @default.
- W2912269398 doi "https://doi.org/10.4062/biomolther.2018.213" @default.
- W2912269398 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6609113" @default.
- W2912269398 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30739426" @default.
- W2912269398 hasPublicationYear "2019" @default.
- W2912269398 type Work @default.
- W2912269398 sameAs 2912269398 @default.
- W2912269398 citedByCount "9" @default.
- W2912269398 countsByYear W29122693982019 @default.
- W2912269398 countsByYear W29122693982020 @default.
- W2912269398 countsByYear W29122693982021 @default.
- W2912269398 countsByYear W29122693982022 @default.
- W2912269398 countsByYear W29122693982023 @default.
- W2912269398 crossrefType "journal-article" @default.
- W2912269398 hasAuthorship W2912269398A5007610160 @default.
- W2912269398 hasAuthorship W2912269398A5044964332 @default.
- W2912269398 hasAuthorship W2912269398A5050499399 @default.
- W2912269398 hasAuthorship W2912269398A5088567252 @default.
- W2912269398 hasAuthorship W2912269398A5090177102 @default.
- W2912269398 hasBestOaLocation W29122693982 @default.
- W2912269398 hasConcept C120069818 @default.
- W2912269398 hasConcept C126322002 @default.
- W2912269398 hasConcept C170493617 @default.
- W2912269398 hasConcept C185592680 @default.
- W2912269398 hasConcept C203014093 @default.
- W2912269398 hasConcept C2776217527 @default.
- W2912269398 hasConcept C2777389121 @default.
- W2912269398 hasConcept C2777525119 @default.
- W2912269398 hasConcept C2778938600 @default.
- W2912269398 hasConcept C2780376393 @default.
- W2912269398 hasConcept C35124327 @default.
- W2912269398 hasConcept C44208683 @default.
- W2912269398 hasConcept C513476851 @default.
- W2912269398 hasConcept C55493867 @default.
- W2912269398 hasConcept C71924100 @default.
- W2912269398 hasConcept C98274493 @default.
- W2912269398 hasConceptScore W2912269398C120069818 @default.
- W2912269398 hasConceptScore W2912269398C126322002 @default.
- W2912269398 hasConceptScore W2912269398C170493617 @default.
- W2912269398 hasConceptScore W2912269398C185592680 @default.
- W2912269398 hasConceptScore W2912269398C203014093 @default.
- W2912269398 hasConceptScore W2912269398C2776217527 @default.
- W2912269398 hasConceptScore W2912269398C2777389121 @default.
- W2912269398 hasConceptScore W2912269398C2777525119 @default.
- W2912269398 hasConceptScore W2912269398C2778938600 @default.