FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912270719> ?p ?o ?g. }

• W2912270719 abstract "Lymphatic vessels collect and transport lymph and pathogens to the draining lymph node (LN) to generate proper immune protection. A layer of macrophages that strategically line the LN subcapsular sinus (SCS) is directly exposed to the afferent lymph and are denoted as SCS macrophages. These macrophages are the frontline of immune defense that interact with lymph-borne antigens. The importance of these macrophages in limiting the spread of pathogens has been demonstrated in both viral and bacterial infection. In anti-microbial responses, these macrophages can directly or indirectly activate other LN innate immune cells to fight against pathogens, as well as activate T cells or B cells for adaptive immunity. As the first layer of immune cells embracing the tumor-derived antigens, SCS macrophages also actively participate in cancer immune regulation. Recent studies have shown that the LNs' SCS macrophage layer is interrupted in disease models. Despite their importance in fighting the spread of pathogens and in activating anti-tumor immunity, the mechanism and the immunological functional consequences for their disruption are not well-understood. Understanding the mechanism of these macrophages will enhance their capability for therapeutic targeting." @default.
• W2912270719 created "2019-02-21" @default.
• W2912270719 creator A5013796517 @default.
• W2912270719 creator A5084774652 @default.
• W2912270719 date "2019-02-28" @default.
• W2912270719 modified "2023-10-13" @default.
• W2912270719 title "Lymph Node Subcapsular Sinus Macrophages as the Frontline of Lymphatic Immune Defense" @default.
• W2912270719 cites W1502600357 @default.
• W2912270719 cites W1598422965 @default.
• W2912270719 cites W1920927643 @default.
• W2912270719 cites W1967994686 @default.
• W2912270719 cites W1969119554 @default.
• W2912270719 cites W1977980568 @default.
• W2912270719 cites W1979373626 @default.
• W2912270719 cites W1984378774 @default.
• W2912270719 cites W1990716542 @default.
• W2912270719 cites W2005631373 @default.
• W2912270719 cites W2008471218 @default.
• W2912270719 cites W2015776459 @default.
• W2912270719 cites W2016055373 @default.
• W2912270719 cites W2019206924 @default.
• W2912270719 cites W2019620892 @default.
• W2912270719 cites W2023880559 @default.
• W2912270719 cites W2024235284 @default.
• W2912270719 cites W2036115786 @default.
• W2912270719 cites W2040788971 @default.
• W2912270719 cites W2056475154 @default.
• W2912270719 cites W2056703680 @default.
• W2912270719 cites W2059528812 @default.
• W2912270719 cites W2062690397 @default.
• W2912270719 cites W2067170256 @default.
• W2912270719 cites W2088058388 @default.
• W2912270719 cites W2088143327 @default.
• W2912270719 cites W2088194700 @default.
• W2912270719 cites W2092787543 @default.
• W2912270719 cites W2094999215 @default.
• W2912270719 cites W2100322007 @default.
• W2912270719 cites W2114780139 @default.
• W2912270719 cites W2122264549 @default.
• W2912270719 cites W2123475341 @default.
• W2912270719 cites W2127936148 @default.
• W2912270719 cites W2136243233 @default.
• W2912270719 cites W2142996956 @default.
• W2912270719 cites W2147285844 @default.
• W2912270719 cites W2158659385 @default.
• W2912270719 cites W2159092116 @default.
• W2912270719 cites W2168628444 @default.
• W2912270719 cites W2169390260 @default.
• W2912270719 cites W2194125047 @default.
• W2912270719 cites W2198386817 @default.
• W2912270719 cites W2232178678 @default.
• W2912270719 cites W2309770165 @default.
• W2912270719 cites W2527008427 @default.
• W2912270719 cites W2536508826 @default.
• W2912270719 cites W2557112439 @default.
• W2912270719 cites W2566874692 @default.
• W2912270719 cites W2592953665 @default.
• W2912270719 cites W2631214962 @default.
• W2912270719 cites W2789838322 @default.
• W2912270719 cites W2793277547 @default.
• W2912270719 cites W2793511401 @default.
• W2912270719 cites W2793641770 @default.
• W2912270719 cites W16411224 @default.
• W2912270719 doi "https://doi.org/10.3389/fimmu.2019.00347" @default.
• W2912270719 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6413714" @default.
• W2912270719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30891035" @default.
• W2912270719 hasPublicationYear "2019" @default.
• W2912270719 type Work @default.
• W2912270719 sameAs 2912270719 @default.
• W2912270719 citedByCount "75" @default.
• W2912270719 countsByYear W29122707192019 @default.
• W2912270719 countsByYear W29122707192020 @default.
• W2912270719 countsByYear W29122707192021 @default.
• W2912270719 countsByYear W29122707192022 @default.
• W2912270719 countsByYear W29122707192023 @default.
• W2912270719 crossrefType "journal-article" @default.
• W2912270719 hasAuthorship W2912270719A5013796517 @default.
• W2912270719 hasAuthorship W2912270719A5084774652 @default.
• W2912270719 hasBestOaLocation W29122707191 @default.
• W2912270719 hasConcept C125864771 @default.
• W2912270719 hasConcept C136449434 @default.
• W2912270719 hasConcept C142724271 @default.
• W2912270719 hasConcept C147483822 @default.
• W2912270719 hasConcept C181152851 @default.
• W2912270719 hasConcept C193419808 @default.
• W2912270719 hasConcept C202751555 @default.
• W2912270719 hasConcept C203014093 @default.
• W2912270719 hasConcept C2779244956 @default.
• W2912270719 hasConcept C2779341262 @default.
• W2912270719 hasConcept C2779720271 @default.
• W2912270719 hasConcept C2780849966 @default.
• W2912270719 hasConcept C55493867 @default.
• W2912270719 hasConcept C71924100 @default.
• W2912270719 hasConcept C86803240 @default.
• W2912270719 hasConcept C8891405 @default.
• W2912270719 hasConceptScore W2912270719C125864771 @default.
• W2912270719 hasConceptScore W2912270719C136449434 @default.
• W2912270719 hasConceptScore W2912270719C142724271 @default.
• W2912270719 hasConceptScore W2912270719C147483822 @default.
• W2912270719 hasConceptScore W2912270719C181152851 @default.

• next