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• W2912287004 abstract "Systemic sclerosis (SSc) is a complex rheumatologic autoimmune disease in which inflammation, fibrosis, and vasculopathy share several pathogenic pathways that lead to skin and internal organ damage. Recent findings regarding the participation and interaction of the innate and acquired immune system have led to a better understanding of the pathogenesis of the disease and to the identification of new therapeutic targets, many of which have been tested in preclinical and clinical trials with varying results. In this manuscript, we review the state of the art of the pathogenesis of this disease and discuss the main therapeutic targets related to each pathogenic mechanism that have been discovered so far." @default.
• W2912287004 created "2019-02-21" @default.
• W2912287004 creator A5011906191 @default.
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• W2912287004 creator A5082513350 @default.
• W2912287004 date "2019-01-23" @default.
• W2912287004 modified "2023-10-18" @default.
• W2912287004 title "Systemic Sclerosis Pathogenesis and Emerging Therapies, beyond the Fibroblast" @default.
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