Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912292313> ?p ?o ?g. }
- W2912292313 endingPage "1141" @default.
- W2912292313 startingPage "1134" @default.
- W2912292313 abstract "Inguinal lymph node metastases (ILNM) from rectal adenocarcinoma are rare and staged as systemic disease. This study aimed to provide insight into the treatment and prognosis of ILNM from rectal adenocarcinoma.All patients with a diagnosis of synchronous or metachronous ILNM from rectal adenocarcinoma between January 2005 and March 2017 were retrospectively reviewed.The study identified 27 patients with ILNM (15 with synchronous and 12 with metachronous disease). After discussion by a multidisciplinary tumor board, 19 patients were treated with curative intent, 17 of whom underwent inguinal lymph node dissection. Of the 17 patients, 12 had locally advanced rectal cancer (LARC) with isolated ILNM, 3 had LARC and metastases elsewhere, and 2 had locally recurrent rectal cancer (LRRC). The median overall survival (OS) for all the patients treated with curative intent was 27 months [95% confidence interval (CI) 11.6-42.4 months], with a 5-year OS rate of 34%. The median OS for the patients with LARC and isolated ILNM (n = 12) was 74 months (95% CI 18.0-130.0 months), with a 5-year OS rate of 52%. All the patients with metastases elsewhere (n = 3) or LRRC (n = 2) experienced recurrent systemic disease. Eight patients were treated with palliative intent. The median OS for this group was 13 months (95% CI 1.9-24.1 months), with a 3-year OS rate of 0%.Clinicians should not consider ILNM as an incurable systemic disease. Patients with primary rectal cancer and solitary ILNM who were eligible for curative surgical treatment had a 5-year survival rate of 52%. The prognosis for patients with additional systemic metastases or LRRC is worse, and the benefit of surgery is unclear." @default.
- W2912292313 created "2019-02-21" @default.
- W2912292313 creator A5003594769 @default.
- W2912292313 creator A5013432555 @default.
- W2912292313 creator A5024551229 @default.
- W2912292313 creator A5054472237 @default.
- W2912292313 creator A5066354467 @default.
- W2912292313 creator A5071697710 @default.
- W2912292313 creator A5072405531 @default.
- W2912292313 date "2019-02-06" @default.
- W2912292313 modified "2023-10-18" @default.
- W2912292313 title "Treatment of Inguinal Lymph Node Metastases in Patients with Rectal Adenocarcinoma" @default.
- W2912292313 cites W1964434580 @default.
- W2912292313 cites W1965418626 @default.
- W2912292313 cites W2000012850 @default.
- W2912292313 cites W2007688765 @default.
- W2912292313 cites W2014174160 @default.
- W2912292313 cites W2039550774 @default.
- W2912292313 cites W2043563075 @default.
- W2912292313 cites W2067137872 @default.
- W2912292313 cites W2077242404 @default.
- W2912292313 cites W2103789431 @default.
- W2912292313 cites W2143125241 @default.
- W2912292313 cites W2152883689 @default.
- W2912292313 cites W2155492044 @default.
- W2912292313 cites W2168727269 @default.
- W2912292313 cites W2509496194 @default.
- W2912292313 cites W2590588030 @default.
- W2912292313 cites W2795718561 @default.
- W2912292313 cites W4244315786 @default.
- W2912292313 doi "https://doi.org/10.1245/s10434-019-07191-4" @default.
- W2912292313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6399178" @default.
- W2912292313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30725310" @default.
- W2912292313 hasPublicationYear "2019" @default.
- W2912292313 type Work @default.
- W2912292313 sameAs 2912292313 @default.
- W2912292313 citedByCount "10" @default.
- W2912292313 countsByYear W29122923132019 @default.
- W2912292313 countsByYear W29122923132020 @default.
- W2912292313 countsByYear W29122923132021 @default.
- W2912292313 countsByYear W29122923132022 @default.
- W2912292313 countsByYear W29122923132023 @default.
- W2912292313 crossrefType "journal-article" @default.
- W2912292313 hasAuthorship W2912292313A5003594769 @default.
- W2912292313 hasAuthorship W2912292313A5013432555 @default.
- W2912292313 hasAuthorship W2912292313A5024551229 @default.
- W2912292313 hasAuthorship W2912292313A5054472237 @default.
- W2912292313 hasAuthorship W2912292313A5066354467 @default.
- W2912292313 hasAuthorship W2912292313A5071697710 @default.
- W2912292313 hasAuthorship W2912292313A5072405531 @default.
- W2912292313 hasBestOaLocation W29122923131 @default.
- W2912292313 hasConcept C121608353 @default.
- W2912292313 hasConcept C126322002 @default.
- W2912292313 hasConcept C141071460 @default.
- W2912292313 hasConcept C146357865 @default.
- W2912292313 hasConcept C151730666 @default.
- W2912292313 hasConcept C2775862295 @default.
- W2912292313 hasConcept C2776283816 @default.
- W2912292313 hasConcept C2779122609 @default.
- W2912292313 hasConcept C2779134260 @default.
- W2912292313 hasConcept C2780140570 @default.
- W2912292313 hasConcept C2780849966 @default.
- W2912292313 hasConcept C2781182431 @default.
- W2912292313 hasConcept C526805850 @default.
- W2912292313 hasConcept C71924100 @default.
- W2912292313 hasConcept C86803240 @default.
- W2912292313 hasConceptScore W2912292313C121608353 @default.
- W2912292313 hasConceptScore W2912292313C126322002 @default.
- W2912292313 hasConceptScore W2912292313C141071460 @default.
- W2912292313 hasConceptScore W2912292313C146357865 @default.
- W2912292313 hasConceptScore W2912292313C151730666 @default.
- W2912292313 hasConceptScore W2912292313C2775862295 @default.
- W2912292313 hasConceptScore W2912292313C2776283816 @default.
- W2912292313 hasConceptScore W2912292313C2779122609 @default.
- W2912292313 hasConceptScore W2912292313C2779134260 @default.
- W2912292313 hasConceptScore W2912292313C2780140570 @default.
- W2912292313 hasConceptScore W2912292313C2780849966 @default.
- W2912292313 hasConceptScore W2912292313C2781182431 @default.
- W2912292313 hasConceptScore W2912292313C526805850 @default.
- W2912292313 hasConceptScore W2912292313C71924100 @default.
- W2912292313 hasConceptScore W2912292313C86803240 @default.
- W2912292313 hasIssue "4" @default.
- W2912292313 hasLocation W29122923131 @default.
- W2912292313 hasLocation W29122923132 @default.
- W2912292313 hasLocation W29122923133 @default.
- W2912292313 hasLocation W29122923134 @default.
- W2912292313 hasLocation W29122923135 @default.
- W2912292313 hasLocation W29122923136 @default.
- W2912292313 hasLocation W29122923137 @default.
- W2912292313 hasOpenAccess W2912292313 @default.
- W2912292313 hasPrimaryLocation W29122923131 @default.
- W2912292313 hasRelatedWork W2051166227 @default.
- W2912292313 hasRelatedWork W2053411225 @default.
- W2912292313 hasRelatedWork W2316816868 @default.
- W2912292313 hasRelatedWork W2362744459 @default.
- W2912292313 hasRelatedWork W2380323308 @default.
- W2912292313 hasRelatedWork W2419181597 @default.
- W2912292313 hasRelatedWork W3027162638 @default.