Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912294247> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2912294247 endingPage "22" @default.
- W2912294247 startingPage "22" @default.
- W2912294247 abstract "The balance of lung extravascular water depends upon the control of blood flow in the alveolar distribution vessels that feed downstream two districts placed in parallel, the corner vessels and the alveolar septal network. The occurrence of an edemagenic condition appears critical as an increase in extravascular water endangers the thinness of the air–blood barrier, thus negatively affecting the diffusive capacity of the lung. We exposed anesthetized rabbits to an edemagenic factor (12% hypoxia) for 120 min and followed by in vivo imaging the micro-vascular morphology through a “pleural window” using a stereo microscope at a magnification of 15× (resolution of 7.2 μm). We measured the change in diameter of distribution vessels (50–200 μm) and corner vessels (<50 μm). On average, hypoxia caused a significant decrease in diameter of both smaller distribution vessels (about ~50%) and corner vessels (about ~25%) at 30 min. After 120 min, reperfusion occurred. Regional differences in perivascular interstitial volume were observed and could be correlated with differences in blood flow control. To understand such difference, we modelled imaged alveolar capillary units, obtained by Voronoi method, integrating microvascular pressure parameters with capillary filtration. Results of the analysis suggested that at 120 min, alveolar blood flow was diverted to the corner vessels in larger alveoli, which were found also to undergo a greater filtration indicating greater proneness to develop lung edema." @default.
- W2912294247 created "2019-02-21" @default.
- W2912294247 creator A5079166399 @default.
- W2912294247 creator A5080763224 @default.
- W2912294247 creator A5085074218 @default.
- W2912294247 date "2019-01-22" @default.
- W2912294247 modified "2023-09-27" @default.
- W2912294247 title "Understanding Vasomotion of Lung Microcirculation by In Vivo Imaging" @default.
- W2912294247 cites W2028781868 @default.
- W2912294247 cites W2045110714 @default.
- W2912294247 cites W2048448755 @default.
- W2912294247 cites W2077112541 @default.
- W2912294247 cites W2077335292 @default.
- W2912294247 cites W2091055733 @default.
- W2912294247 cites W2109316100 @default.
- W2912294247 cites W2113419503 @default.
- W2912294247 cites W2113566585 @default.
- W2912294247 cites W2129145903 @default.
- W2912294247 cites W2131364104 @default.
- W2912294247 cites W2133409498 @default.
- W2912294247 cites W2136596343 @default.
- W2912294247 cites W2137135934 @default.
- W2912294247 cites W2137137239 @default.
- W2912294247 cites W2154054141 @default.
- W2912294247 cites W2162139867 @default.
- W2912294247 cites W2186097020 @default.
- W2912294247 cites W2331102915 @default.
- W2912294247 cites W2412607459 @default.
- W2912294247 cites W2602136859 @default.
- W2912294247 cites W2744158231 @default.
- W2912294247 cites W4255576461 @default.
- W2912294247 doi "https://doi.org/10.3390/jimaging5020022" @default.
- W2912294247 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8320900" @default.
- W2912294247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34460470" @default.
- W2912294247 hasPublicationYear "2019" @default.
- W2912294247 type Work @default.
- W2912294247 sameAs 2912294247 @default.
- W2912294247 citedByCount "12" @default.
- W2912294247 countsByYear W29122942472019 @default.
- W2912294247 countsByYear W29122942472021 @default.
- W2912294247 countsByYear W29122942472022 @default.
- W2912294247 countsByYear W29122942472023 @default.
- W2912294247 crossrefType "journal-article" @default.
- W2912294247 hasAuthorship W2912294247A5079166399 @default.
- W2912294247 hasAuthorship W2912294247A5080763224 @default.
- W2912294247 hasAuthorship W2912294247A5085074218 @default.
- W2912294247 hasBestOaLocation W29122942471 @default.
- W2912294247 hasConcept C105702510 @default.
- W2912294247 hasConcept C126322002 @default.
- W2912294247 hasConcept C12722491 @default.
- W2912294247 hasConcept C142724271 @default.
- W2912294247 hasConcept C150903083 @default.
- W2912294247 hasConcept C158846371 @default.
- W2912294247 hasConcept C164705383 @default.
- W2912294247 hasConcept C185592680 @default.
- W2912294247 hasConcept C207001950 @default.
- W2912294247 hasConcept C27101514 @default.
- W2912294247 hasConcept C2777714996 @default.
- W2912294247 hasConcept C71924100 @default.
- W2912294247 hasConcept C86803240 @default.
- W2912294247 hasConceptScore W2912294247C105702510 @default.
- W2912294247 hasConceptScore W2912294247C126322002 @default.
- W2912294247 hasConceptScore W2912294247C12722491 @default.
- W2912294247 hasConceptScore W2912294247C142724271 @default.
- W2912294247 hasConceptScore W2912294247C150903083 @default.
- W2912294247 hasConceptScore W2912294247C158846371 @default.
- W2912294247 hasConceptScore W2912294247C164705383 @default.
- W2912294247 hasConceptScore W2912294247C185592680 @default.
- W2912294247 hasConceptScore W2912294247C207001950 @default.
- W2912294247 hasConceptScore W2912294247C27101514 @default.
- W2912294247 hasConceptScore W2912294247C2777714996 @default.
- W2912294247 hasConceptScore W2912294247C71924100 @default.
- W2912294247 hasConceptScore W2912294247C86803240 @default.
- W2912294247 hasFunder F4320321499 @default.
- W2912294247 hasIssue "2" @default.
- W2912294247 hasLocation W29122942471 @default.
- W2912294247 hasLocation W29122942472 @default.
- W2912294247 hasLocation W29122942473 @default.
- W2912294247 hasOpenAccess W2912294247 @default.
- W2912294247 hasPrimaryLocation W29122942471 @default.
- W2912294247 hasRelatedWork W1915676180 @default.
- W2912294247 hasRelatedWork W2047179266 @default.
- W2912294247 hasRelatedWork W2209698604 @default.
- W2912294247 hasRelatedWork W2412343912 @default.
- W2912294247 hasRelatedWork W2415992656 @default.
- W2912294247 hasRelatedWork W2912294247 @default.
- W2912294247 hasRelatedWork W3137208882 @default.
- W2912294247 hasRelatedWork W4286855209 @default.
- W2912294247 hasRelatedWork W4366237001 @default.
- W2912294247 hasRelatedWork W2121123540 @default.
- W2912294247 hasVolume "5" @default.
- W2912294247 isParatext "false" @default.
- W2912294247 isRetracted "false" @default.
- W2912294247 magId "2912294247" @default.
- W2912294247 workType "article" @default.