Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912295721> ?p ?o ?g. }
- W2912295721 abstract "Spinal cord injury (SCI) remains a huge medical problem nowadays as there is no hospital providing the versatile strategies for repairing central nervous system and restoring function. Herein, we focused on PC-12 cells as an important research tool and studied the potential role of resveratrol (RSV) in inflammation induced by LPS. RSV improved inflammatory injury and functional recovery in rat model of SCI. RSV inhibited LPS-induced inflammatory injury in PC-12 cells via increasing viability, decreasing apoptosis, and suppressing IL-1β, IL-6, and TNF-α expression. miR-132 was down-regulated after LPS treatment but up-regulated after RSV administration. miR-132 silence curbed the protective effect of RSV. The results including increase of cell growth, suppression of inflammatory response, and blocking of NF-κB and p38MAPK pathways produced by RSV were all reversed by miR-132 silence. RSV could up-regulate miR-132 and further ameliorate inflammatory response in PC-12 cells by inhibiting NF-κB and p38MAPK pathways." @default.
- W2912295721 created "2019-02-21" @default.
- W2912295721 creator A5008659449 @default.
- W2912295721 creator A5017624230 @default.
- W2912295721 creator A5023755657 @default.
- W2912295721 creator A5035082701 @default.
- W2912295721 creator A5042771213 @default.
- W2912295721 creator A5057036130 @default.
- W2912295721 date "2019-01-28" @default.
- W2912295721 modified "2023-10-18" @default.
- W2912295721 title "Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model" @default.
- W2912295721 cites W1534551308 @default.
- W2912295721 cites W1827438416 @default.
- W2912295721 cites W1970024238 @default.
- W2912295721 cites W1980677407 @default.
- W2912295721 cites W1982192193 @default.
- W2912295721 cites W2003985105 @default.
- W2912295721 cites W2004763680 @default.
- W2912295721 cites W2006517495 @default.
- W2912295721 cites W2010207650 @default.
- W2912295721 cites W2013612137 @default.
- W2912295721 cites W2013700695 @default.
- W2912295721 cites W2013852511 @default.
- W2912295721 cites W2018969070 @default.
- W2912295721 cites W2020433921 @default.
- W2912295721 cites W2023053568 @default.
- W2912295721 cites W2052244093 @default.
- W2912295721 cites W2064947977 @default.
- W2912295721 cites W2078575160 @default.
- W2912295721 cites W2117499294 @default.
- W2912295721 cites W2135919238 @default.
- W2912295721 cites W2138134399 @default.
- W2912295721 cites W2163352169 @default.
- W2912295721 cites W2244373518 @default.
- W2912295721 cites W2277645594 @default.
- W2912295721 cites W2403236246 @default.
- W2912295721 cites W2517506637 @default.
- W2912295721 cites W2604885298 @default.
- W2912295721 cites W2738140292 @default.
- W2912295721 cites W2743254891 @default.
- W2912295721 cites W2753695139 @default.
- W2912295721 cites W2757755029 @default.
- W2912295721 cites W2770927142 @default.
- W2912295721 cites W2774620453 @default.
- W2912295721 cites W2787315053 @default.
- W2912295721 cites W2790620274 @default.
- W2912295721 cites W2793638569 @default.
- W2912295721 cites W283604438 @default.
- W2912295721 cites W3023721388 @default.
- W2912295721 doi "https://doi.org/10.1186/s12896-019-0502-1" @default.
- W2912295721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6350285" @default.
- W2912295721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30691440" @default.
- W2912295721 hasPublicationYear "2019" @default.
- W2912295721 type Work @default.
- W2912295721 sameAs 2912295721 @default.
- W2912295721 citedByCount "30" @default.
- W2912295721 countsByYear W29122957212019 @default.
- W2912295721 countsByYear W29122957212020 @default.
- W2912295721 countsByYear W29122957212021 @default.
- W2912295721 countsByYear W29122957212022 @default.
- W2912295721 countsByYear W29122957212023 @default.
- W2912295721 crossrefType "journal-article" @default.
- W2912295721 hasAuthorship W2912295721A5008659449 @default.
- W2912295721 hasAuthorship W2912295721A5017624230 @default.
- W2912295721 hasAuthorship W2912295721A5023755657 @default.
- W2912295721 hasAuthorship W2912295721A5035082701 @default.
- W2912295721 hasAuthorship W2912295721A5042771213 @default.
- W2912295721 hasAuthorship W2912295721A5057036130 @default.
- W2912295721 hasBestOaLocation W29122957211 @default.
- W2912295721 hasConcept C169760540 @default.
- W2912295721 hasConcept C190283241 @default.
- W2912295721 hasConcept C203014093 @default.
- W2912295721 hasConcept C2776816829 @default.
- W2912295721 hasConcept C2776914184 @default.
- W2912295721 hasConcept C2777730290 @default.
- W2912295721 hasConcept C2778334475 @default.
- W2912295721 hasConcept C2778754761 @default.
- W2912295721 hasConcept C2780775167 @default.
- W2912295721 hasConcept C53227056 @default.
- W2912295721 hasConcept C55493867 @default.
- W2912295721 hasConcept C86803240 @default.
- W2912295721 hasConcept C98274493 @default.
- W2912295721 hasConceptScore W2912295721C169760540 @default.
- W2912295721 hasConceptScore W2912295721C190283241 @default.
- W2912295721 hasConceptScore W2912295721C203014093 @default.
- W2912295721 hasConceptScore W2912295721C2776816829 @default.
- W2912295721 hasConceptScore W2912295721C2776914184 @default.
- W2912295721 hasConceptScore W2912295721C2777730290 @default.
- W2912295721 hasConceptScore W2912295721C2778334475 @default.
- W2912295721 hasConceptScore W2912295721C2778754761 @default.
- W2912295721 hasConceptScore W2912295721C2780775167 @default.
- W2912295721 hasConceptScore W2912295721C53227056 @default.
- W2912295721 hasConceptScore W2912295721C55493867 @default.
- W2912295721 hasConceptScore W2912295721C86803240 @default.
- W2912295721 hasConceptScore W2912295721C98274493 @default.
- W2912295721 hasIssue "1" @default.
- W2912295721 hasLocation W29122957211 @default.
- W2912295721 hasLocation W29122957212 @default.
- W2912295721 hasLocation W29122957213 @default.
- W2912295721 hasLocation W29122957214 @default.