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- W2912296272 endingPage "S48" @default.
- W2912296272 startingPage "S36" @default.
- W2912296272 abstract "Currently, there is a dearth of information regarding the degree of particle shedding from breast implants (BIs) and what are the general biological consequences of BI debris. Thus, it is unclear to what degree BI debris compromises the long-term biological performance of BIs. For orthopedic implants, it is well established that the severity of biological reactivity to implant debris governs long-term clinical performance. Orthopedic implant particulate debris is generally in the range of 0.01 to 100 μm in diameter. Implant debris-induced bioreactivity/inflammation is mostly a peri-implant phenomenon caused by local innate immune cells (eg, macrophages) that produce proinflammatory cytokines such as tumor necrosis factor-α, interleukin-1β, interleukin-6, and prostaglandin 2 (PGE2). In orthopedics, there have been few systemic concerns associated with polymeric implant debris (like silicone) other than documented dissemination to remote organs (eg, liver, spleen, etc.) with no known associated pathogenicity. This is not true of metal implant debris where normal (well-functioning) implants can induce systemic reactions such as delayed type hypersensitivity. Diagnostic analysis of orthopedic tissues has focused on innate (macrophage mediated) and adaptive (lymphocyte-mediated hypersensitivity) immune responses. Orthopedic implant debris-associated lymphocyte cancers have not been reported in over 40 years of orthopedic literature. Adaptive immune responses such as hypersensitivity reactions to orthopedic implant debris have been dominated by certain implant types that produce specific kinds of debris (eg, metal-on-metal total joint prostheses). Orthopedic hypersensitivity responses and atypical BI bioreactivity such as BI-associated anaplastic large cell lymphoma share crossover markers for diagnosis. Differentiating normal innate immune reactivity to particles from anaplastic large cell lymphoma reactions from delayed type hypersensitivity reactions to BI-associated implant debris remains unclear but vital to patients and surgeons." @default.
- W2912296272 created "2019-02-21" @default.
- W2912296272 creator A5028897579 @default.
- W2912296272 creator A5057383926 @default.
- W2912296272 creator A5059009873 @default.
- W2912296272 date "2019-01-31" @default.
- W2912296272 modified "2023-10-17" @default.
- W2912296272 title "The Inflammatory Effects of Breast Implant Particulate Shedding: Comparison With Orthopedic Implants" @default.
- W2912296272 cites W115367669 @default.
- W2912296272 cites W134930929 @default.
- W2912296272 cites W1515005371 @default.
- W2912296272 cites W1595194827 @default.
- W2912296272 cites W1897432177 @default.
- W2912296272 cites W1911093849 @default.
- W2912296272 cites W1946707345 @default.
- W2912296272 cites W1965349855 @default.
- W2912296272 cites W1965449438 @default.
- W2912296272 cites W1965621427 @default.
- W2912296272 cites W1967078637 @default.
- W2912296272 cites W1968090295 @default.
- W2912296272 cites W1968620053 @default.
- W2912296272 cites W1973603269 @default.
- W2912296272 cites W1978885686 @default.
- W2912296272 cites W1983241827 @default.
- W2912296272 cites W1983988779 @default.
- W2912296272 cites W1984683170 @default.
- W2912296272 cites W1987426514 @default.
- W2912296272 cites W1988336043 @default.
- W2912296272 cites W1991267506 @default.
- W2912296272 cites W1991953101 @default.
- W2912296272 cites W2001250238 @default.
- W2912296272 cites W2009004909 @default.
- W2912296272 cites W2009800174 @default.
- W2912296272 cites W2011463553 @default.
- W2912296272 cites W2012575225 @default.
- W2912296272 cites W2016213623 @default.
- W2912296272 cites W202141498 @default.
- W2912296272 cites W2023503427 @default.
- W2912296272 cites W2025250376 @default.
- W2912296272 cites W2025807161 @default.
- W2912296272 cites W2033376594 @default.
- W2912296272 cites W2033803883 @default.
- W2912296272 cites W2034487834 @default.
- W2912296272 cites W2035272671 @default.
- W2912296272 cites W2035621856 @default.
- W2912296272 cites W2035726492 @default.
- W2912296272 cites W2036234815 @default.
- W2912296272 cites W2043071176 @default.
- W2912296272 cites W2044613508 @default.
- W2912296272 cites W2049686700 @default.
- W2912296272 cites W2053280667 @default.
- W2912296272 cites W2054595138 @default.
- W2912296272 cites W2057503698 @default.
- W2912296272 cites W2059492476 @default.
- W2912296272 cites W2060880134 @default.
- W2912296272 cites W2060942013 @default.
- W2912296272 cites W2062251277 @default.
- W2912296272 cites W2064620769 @default.
- W2912296272 cites W2067116810 @default.
- W2912296272 cites W2068562565 @default.
- W2912296272 cites W2070069985 @default.
- W2912296272 cites W2074952191 @default.
- W2912296272 cites W2083791849 @default.
- W2912296272 cites W2085538430 @default.
- W2912296272 cites W2086530378 @default.
- W2912296272 cites W2089040209 @default.
- W2912296272 cites W2095997731 @default.
- W2912296272 cites W2097517073 @default.
- W2912296272 cites W2103907018 @default.
- W2912296272 cites W2104047630 @default.
- W2912296272 cites W2107292547 @default.
- W2912296272 cites W2110054888 @default.
- W2912296272 cites W2117817228 @default.
- W2912296272 cites W2120820674 @default.
- W2912296272 cites W2126384811 @default.
- W2912296272 cites W2130111797 @default.
- W2912296272 cites W2132045171 @default.
- W2912296272 cites W2135996232 @default.
- W2912296272 cites W2136738331 @default.
- W2912296272 cites W2144121313 @default.
- W2912296272 cites W2144629070 @default.
- W2912296272 cites W2146188661 @default.
- W2912296272 cites W2148028415 @default.
- W2912296272 cites W2151412727 @default.
- W2912296272 cites W2159714543 @default.
- W2912296272 cites W2167768112 @default.
- W2912296272 cites W2170143415 @default.
- W2912296272 cites W2182247463 @default.
- W2912296272 cites W2184102018 @default.
- W2912296272 cites W2187511444 @default.
- W2912296272 cites W2237519910 @default.
- W2912296272 cites W2273695516 @default.
- W2912296272 cites W2280525057 @default.
- W2912296272 cites W2283018942 @default.
- W2912296272 cites W2289093893 @default.
- W2912296272 cites W2291775813 @default.
- W2912296272 cites W2322007314 @default.
- W2912296272 cites W2405367167 @default.