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- W2912331311 abstract "Abstract Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. UA has a widespread pharmacologic effect, including antitumor, anti‐inflammatory, anti‐oxidant, anti‐apoptotic, anti‐allergy, and anti‐carcinogenic effects. UA can be used as an alternative medicine for the treatment and prevention of many diseases. However, the bioavailability of UA by oral administration is low since it is absorbed by the intestine through passive diffusion. Therefore, some novel technologies are used to produce UA preparations that can change the pharmacokinetics process and increase its solubility and bioavailability. At present, pharmacokinetic studies on UA are few. In this paper, we will review the pharmacokinetics features of free UA and some novel UA preparations in vitro and in vivo , in order to provide a reference for rational utilization and drug design of UA." @default.
- W2912331311 created "2019-02-21" @default.
- W2912331311 creator A5015181477 @default.
- W2912331311 date "2019-01-21" @default.
- W2912331311 modified "2023-10-17" @default.
- W2912331311 title "Ursolic acid: Pharmacokinetics process<i>in vitro</i>and<i>in vivo</i>, a mini review" @default.
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- W2912331311 doi "https://doi.org/10.1002/ardp.201800222" @default.
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