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- W2912353668 abstract "Carrageenan is a thickening or emulsifying agent in food and medicinal products that is derived from red seaweed algae. Adverse reactions to carrageenan have been reported sparingly with barium enema solution, but may also be associated with adverse reactions to food. A 12 year old male patient presented to a community allergy clinic with an immediate, suspected allergic, reaction to ice cream. The allergy evaluation included skin testing, and oral challenges to a sample of the ice cream, ASA, and carrageenan. Skin testing to common foods was negative. An oral challenge in office to a sample of the ice cream resulted in chest tightness and throat discomfort. Salicylates were suspected as a potential trigger, ruled out on subsequent ASA oral challenge. The patient later had a reaction to whipped cream, which among other ingredients previously ruled out for allergy, contained carrageenan. Skin testing to carrageenan revealed a borderline response. A blinded oral challenge to powdered carrageenan in a food vehicle was carried out. The first oral challenge dose containing 0.1 g elicited symptoms of chest pain and a reduction of 10% in FEV1 from baseline, which reversed by 14% post-bronchodilator, confirming an immediate allergic response. Carrageenan avoidance was recommended. Information was given to the family on avoidance of carrageenan in food products and medications. Carrageenan may account for allergic reactions to foods or medications in the absence of other allergic triggers. Potential carrageenan sources include dairy products, milk alternatives, protein supplements, meat products, and oral medications." @default.
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- W2912353668 date "2019-02-01" @default.
- W2912353668 modified "2023-10-14" @default.
- W2912353668 title "When Milk isn't the Problem—Carrageenan as a Trigger for Allergic Reactions to Dairy Products" @default.
- W2912353668 doi "https://doi.org/10.1016/j.jaci.2018.12.225" @default.
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