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- W2912354751 endingPage "338" @default.
- W2912354751 startingPage "323" @default.
- W2912354751 abstract "As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted towards alternative therapies for treating infections. Although several alternatives already exist in nature, the challenge is to implement them in clinical use. Advancements within biotechnology, genetic engineering, and synthetic chemistry have opened up new avenues towards the search for therapies that can substitute for antibiotics. This review provides an introduction to the various promising approaches that have been adopted in this regard. Whilst the use of bacteriophages and antibodies has been partly implemented, other promising strategies, such as probiotics, lysins, and antimicrobial peptides, are in various stages of development. Propitious concepts such as genetically modified phages, antibacterial oligonucleotides, and CRISPR-Cas9 are also discussed." @default.
- W2912354751 created "2019-02-21" @default.
- W2912354751 creator A5039034011 @default.
- W2912354751 creator A5047645403 @default.
- W2912354751 creator A5067510341 @default.
- W2912354751 creator A5077946293 @default.
- W2912354751 date "2019-04-01" @default.
- W2912354751 modified "2023-10-11" @default.
- W2912354751 title "Alternatives to Conventional Antibiotics in the Era of Antimicrobial Resistance" @default.
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