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• W2912368167 abstract "Glioblastoma (GBM) is the most common primary brain tumor. Despite aggressive treatment, GBM almost always recurs. The current standard-of-care for treatment of newly diagnosed GBM has remained relatively unchanged since 2005: maximal safe resection followed by concomitant chemoradiation (CRT) with temozolomide (TMZ), and subsequent adjuvant TMZ. In 2011, the first-generation tumor treating fields (TTF) device, known at the time as the NovoTTF-100A System (renamed Optune), was approved by the Food and Drug Administration (FDA) for treatment of recurrent GBM. The TTF device was subsequently approved as an adjuvant therapy for newly-diagnosed GBM in 2015. The following is a review of the TTF device, including evidence supporting its use and limitations." @default.
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• W2912368167 date "2019-02-02" @default.
• W2912368167 modified "2023-10-14" @default.
• W2912368167 title "Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review" @default.
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• W2912368167 doi "https://doi.org/10.3390/cancers11020174" @default.
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