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- W2912370153 abstract "Background: On the printable side, thermal printer paper contains bisphenol A (BPA) at high concentration, i.e. touching the paper is similar to touching the pure chemical. Large amounts of BPA could be transferred to the skin, particularly compared to oral uptake. Aims: Measurement of the amount of BPA transferred from the paper to the skin and entering the skin to an extent that it can no longer be washed off. Methods: After touching the paper, fingers were extracted with ethanol. They were also extracted with a delay to determine the rate of BPA penetrating the skin to an extent to become non-extractable. Results: Roughly 1 µg BPA was transferred from the paper to a finger pad, depending on skin properties. It entered the skin at a rate depending on the type of contact. BPA applied as a solution in ethanol became non-extractable in less than 2 h. Dry contact caused slower or reduced uptake: 0.09 µg BPA entered per hour and finger pad, from which an uptake of some 70 µg per day was extrapolated for a person repeatedly in contact with thermal printing paper for 10 h/d. Conclusions: The experiments did not enable any conclusion on uptake into human metabolism. However, once the BPA can no longer be washed off, it is likely to accumulate in the skin and has almost unlimited time for deeper penetration. Current tests on transdermal uptake are limited to around a day, which might underestimate the time available in reality." @default.
- W2912370153 created "2019-02-21" @default.
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- W2912370153 date "2013-09-19" @default.
- W2912370153 modified "2023-09-26" @default.
- W2912370153 title "Dermal uptake of bisphenol A from thermal printing paper" @default.
- W2912370153 doi "https://doi.org/10.1289/isee.2013.s-2-37-02" @default.
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