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- W2912379554 startingPage "1802045" @default.
- W2912379554 abstract "The ability to cryopreserve natural killer (NK) cells has a significant potential in modern cancer immunotherapy. Current cryopreservation protocols cause deterioration in NK cell viability and functionality. This work reports the preservation of human cytokine-activated NK cell viability and function following cryopreservation using a cocktail of biocompatible bioinspired cryoprotectants (i.e., dextran and carboxylated ε-poly-L-lysine). Results demonstrate that the recovered NK cells after cryopreservation and rewarming maintain their viability immediately after thawing at a comparable level to control (dimethyl sulfoxide-based cryopreservation). Although, their viability drops in the first day in culture compared to controls, the cells grow back to a comparable level to controls after 1 week in culture. In addition, the anti-tumor functional activity of recovered NK cells demonstrates higher cytotoxic potency against leukemia cells compared to control. This approach presents a new direction for NK cell preservation, focusing on function and potentially enabling storage and distribution for cancer immunotherapy." @default.
- W2912379554 created "2019-02-21" @default.
- W2912379554 creator A5004548683 @default.
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- W2912379554 date "2019-01-27" @default.
- W2912379554 modified "2023-10-16" @default.
- W2912379554 title "Bioinspired Preservation of Natural Killer Cells for Cancer Immunotherapy" @default.
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- W2912379554 cites W1973587141 @default.
- W2912379554 cites W1974816245 @default.
- W2912379554 cites W1982433646 @default.
- W2912379554 cites W1985785496 @default.
- W2912379554 cites W1994123472 @default.
- W2912379554 cites W2010055592 @default.
- W2912379554 cites W2010466691 @default.
- W2912379554 cites W2011762466 @default.
- W2912379554 cites W2012695162 @default.
- W2912379554 cites W2014403060 @default.
- W2912379554 cites W2017996877 @default.
- W2912379554 cites W2019941436 @default.
- W2912379554 cites W2024483330 @default.
- W2912379554 cites W2024574893 @default.
- W2912379554 cites W2028591128 @default.
- W2912379554 cites W2030855909 @default.
- W2912379554 cites W2036088843 @default.
- W2912379554 cites W2038863086 @default.
- W2912379554 cites W2039958325 @default.
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- W2912379554 cites W2044655073 @default.
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- W2912379554 cites W2064894578 @default.
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- W2912379554 cites W2073300038 @default.
- W2912379554 cites W2076386077 @default.
- W2912379554 cites W2080004065 @default.
- W2912379554 cites W2085010800 @default.
- W2912379554 cites W2089386492 @default.
- W2912379554 cites W2089522209 @default.
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- W2912379554 cites W2145583247 @default.
- W2912379554 cites W2146313292 @default.
- W2912379554 cites W2153370986 @default.
- W2912379554 cites W2183811921 @default.
- W2912379554 cites W2187957635 @default.
- W2912379554 cites W2221432805 @default.
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- W2912379554 cites W2332442803 @default.
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- W2912379554 cites W2337303134 @default.
- W2912379554 cites W2340382890 @default.
- W2912379554 cites W2395532360 @default.
- W2912379554 cites W2510732513 @default.
- W2912379554 cites W2515812752 @default.
- W2912379554 cites W2551850252 @default.
- W2912379554 cites W2571352594 @default.
- W2912379554 cites W2585086547 @default.
- W2912379554 cites W2607891440 @default.
- W2912379554 cites W2613182052 @default.
- W2912379554 cites W2618174085 @default.
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- W2912379554 doi "https://doi.org/10.1002/advs.201802045" @default.
- W2912379554 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6425501" @default.
- W2912379554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30937270" @default.
- W2912379554 hasPublicationYear "2019" @default.
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