FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912382250> ?p ?o ?g. }

• W2912382250 abstract "Atherosclerosis of the aorta and coronary arteries is still one of the major causes of death. We recently reported obesity paradox between body mass index and atherosclerosis of the aortas (AA) in morbidly obese decedent patients. The cause of this obesity paradox is unknown. The aim of the present study was to carry out genomic microarray analysis to determine gene expression profiles in the aortas of morbidly obese decedents with either mild or severe atherosclerosis of the aorta.Microarray studies using Affymetrix GeneChips Clariom D Human array chips were performed on the aortas obtained from 6 morbidly obese decedents, 3 of whom had minimal AA and 3 who had severe disease.Group 1 (severe AA) and group 2 (mild AA) included 3 patients each. The patients were matched by age and body mass index. There were significant (P<0.005) differences in the expressions of 1067 genes between groups 1 and 2, including 602 upregulated and 465 downregulated genes.Our data show significantly different gene signatures between morbidly obese decedents who have mild or severe AA, suggesting that genetic factors may be important contributors to the obesity paradox as it relates to aortic atherosclerosis. Further studies are warranted to define differences in protein expression in the aortas of these 2 groups to further elucidate the cause of this obesity paradox." @default.
• W2912382250 created "2019-02-21" @default.
• W2912382250 creator A5003576962 @default.
• W2912382250 creator A5012238012 @default.
• W2912382250 creator A5026181133 @default.
• W2912382250 creator A5044705669 @default.
• W2912382250 creator A5070076002 @default.
• W2912382250 creator A5070808366 @default.
• W2912382250 creator A5082671116 @default.
• W2912382250 date "2019-03-01" @default.
• W2912382250 modified "2023-09-24" @default.
• W2912382250 title "Genomic Analysis of an Obesity Paradox: A Microarray Study of the Aortas of Morbidly Obese Decedents With Mild and Severe Atherosclerosis" @default.
• W2912382250 cites W1991879383 @default.
• W2912382250 cites W2015882577 @default.
• W2912382250 cites W2050289032 @default.
• W2912382250 cites W2075637348 @default.
• W2912382250 cites W2125065061 @default.
• W2912382250 cites W2137322828 @default.
• W2912382250 cites W2346183065 @default.
• W2912382250 cites W2394915560 @default.
• W2912382250 cites W2421653118 @default.
• W2912382250 cites W2517840953 @default.
• W2912382250 cites W2519194391 @default.
• W2912382250 cites W2559068506 @default.
• W2912382250 cites W2624472631 @default.
• W2912382250 cites W2773188710 @default.
• W2912382250 cites W2783116295 @default.
• W2912382250 doi "https://doi.org/10.1097/hpc.0000000000000169" @default.
• W2912382250 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6375103" @default.
• W2912382250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30747767" @default.
• W2912382250 hasPublicationYear "2019" @default.
• W2912382250 type Work @default.
• W2912382250 sameAs 2912382250 @default.
• W2912382250 citedByCount "4" @default.
• W2912382250 countsByYear W29123822502020 @default.
• W2912382250 countsByYear W29123822502021 @default.
• W2912382250 countsByYear W29123822502022 @default.
• W2912382250 crossrefType "journal-article" @default.
• W2912382250 hasAuthorship W2912382250A5003576962 @default.
• W2912382250 hasAuthorship W2912382250A5012238012 @default.
• W2912382250 hasAuthorship W2912382250A5026181133 @default.
• W2912382250 hasAuthorship W2912382250A5044705669 @default.
• W2912382250 hasAuthorship W2912382250A5070076002 @default.
• W2912382250 hasAuthorship W2912382250A5070808366 @default.
• W2912382250 hasAuthorship W2912382250A5082671116 @default.
• W2912382250 hasBestOaLocation W29123822502 @default.
• W2912382250 hasConcept C104317684 @default.
• W2912382250 hasConcept C126322002 @default.
• W2912382250 hasConcept C134018914 @default.
• W2912382250 hasConcept C142724271 @default.
• W2912382250 hasConcept C150194340 @default.
• W2912382250 hasConcept C164705383 @default.
• W2912382250 hasConcept C186836561 @default.
• W2912382250 hasConcept C2779980429 @default.
• W2912382250 hasConcept C2780221984 @default.
• W2912382250 hasConcept C3019948525 @default.
• W2912382250 hasConcept C511355011 @default.
• W2912382250 hasConcept C54355233 @default.
• W2912382250 hasConcept C544821477 @default.
• W2912382250 hasConcept C60644358 @default.
• W2912382250 hasConcept C71924100 @default.
• W2912382250 hasConcept C8415881 @default.
• W2912382250 hasConcept C86803240 @default.
• W2912382250 hasConcept C90924648 @default.
• W2912382250 hasConceptScore W2912382250C104317684 @default.
• W2912382250 hasConceptScore W2912382250C126322002 @default.
• W2912382250 hasConceptScore W2912382250C134018914 @default.
• W2912382250 hasConceptScore W2912382250C142724271 @default.
• W2912382250 hasConceptScore W2912382250C150194340 @default.
• W2912382250 hasConceptScore W2912382250C164705383 @default.
• W2912382250 hasConceptScore W2912382250C186836561 @default.
• W2912382250 hasConceptScore W2912382250C2779980429 @default.
• W2912382250 hasConceptScore W2912382250C2780221984 @default.
• W2912382250 hasConceptScore W2912382250C3019948525 @default.
• W2912382250 hasConceptScore W2912382250C511355011 @default.
• W2912382250 hasConceptScore W2912382250C54355233 @default.
• W2912382250 hasConceptScore W2912382250C544821477 @default.
• W2912382250 hasConceptScore W2912382250C60644358 @default.
• W2912382250 hasConceptScore W2912382250C71924100 @default.
• W2912382250 hasConceptScore W2912382250C8415881 @default.
• W2912382250 hasConceptScore W2912382250C86803240 @default.
• W2912382250 hasConceptScore W2912382250C90924648 @default.
• W2912382250 hasLocation W29123822501 @default.
• W2912382250 hasLocation W29123822502 @default.
• W2912382250 hasLocation W29123822503 @default.
• W2912382250 hasLocation W29123822504 @default.
• W2912382250 hasOpenAccess W2912382250 @default.
• W2912382250 hasPrimaryLocation W29123822501 @default.
• W2912382250 hasRelatedWork W2017781292 @default.
• W2912382250 hasRelatedWork W2504937224 @default.
• W2912382250 hasRelatedWork W2611403665 @default.
• W2912382250 hasRelatedWork W2798098524 @default.
• W2912382250 hasRelatedWork W2897534691 @default.
• W2912382250 hasRelatedWork W2897565388 @default.
• W2912382250 hasRelatedWork W3011119328 @default.
• W2912382250 hasRelatedWork W4241707563 @default.
• W2912382250 hasRelatedWork W4251710449 @default.
• W2912382250 hasRelatedWork W4285490262 @default.
• W2912382250 isParatext "false" @default.
• W2912382250 isRetracted "false" @default.

• next