FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912398052> ?p ?o ?g. }

• W2912398052 endingPage "37" @default.
• W2912398052 startingPage "37" @default.
• W2912398052 abstract "To the general public, the term grey matter is almost synonymous with the brain, although this prominence comes at the expense of white matter, which has a much lower profile. But for Bernard Zalc and Florence Rosier, white matter is like white gold, forming rich milky veins through our brains, with its own vital role and its own mysteries to explore. In Myelin: The Brain's Supercharger they attempt to shed some light on these mysteries and make a case for this long-neglected white gold. Zalc and Rosier provide a thorough description of how myelin accelerates the transmission of nerve impulses, how it was discovered, its evolution, and how myelination occurs within the womb. However, their case for the importance of white matter falls back on discussion of myelin-related conditions—not just multiple sclerosis but also Charcot-Marie-Tooth syndrome, Guillain-Barre syndrome, and Gerstmann syndrome, among others—each highlighting the need for a more thorough understanding of myelin disruption. Zalc and Rosier draw on a range of research that suggests myelin has a wider role than is generally appreciated. They cite research showing that the arcuate fasciculus, which connects the visual areas to the language areas, is more developed and probably more myelinated in people who have learned to read, including those who learned to read as adults, compared with non-readers. Similarly, myelin, and the oligodendrocytes that produce it, might have a role in psychiatric disease: certain white matter tracts have been observed to exhibit volume loss and disarray in patients experiencing their first episodes of schizophrenia, suggesting that this could be a cause of the condition rather than a consequence or an effect of treatment. Similar abnormalities in white matter have been linked to bipolar disorder and depression, and other studies have shown a correlation between an individual's psychological resilience and the integrity of their corpus callosum white matter. Although at the time of their discovery glial cells were dismissed as so-called neuronal glue, this idea has been refuted over the past 20 years. Rather than simply having a nourishing and metabolic role, it is now clear that white matter—and in particular, the myelin-producing cells in the peripheral nervous system and CNS—has a far more complex role to play. Zalc and Rosier argue that myelin disruption is implicated in a variety of neuropsychiatric disorders, and we lack integrated and coherent models that explain the pathological processes at work. The authors suggest that there are many exciting research avenues surrounding this once-neglected area, with a potential gold rush of discoveries awaiting future researchers." @default.
• W2912398052 created "2019-02-21" @default.
• W2912398052 creator A5014986104 @default.
• W2912398052 date "2020-01-01" @default.
• W2912398052 modified "2023-09-27" @default.
• W2912398052 title "After the Gold Rush" @default.
• W2912398052 cites W3027582500 @default.
• W2912398052 doi "https://doi.org/10.1016/s1474-4422(19)30071-7" @default.
• W2912398052 hasPublicationYear "2020" @default.
• W2912398052 type Work @default.
• W2912398052 sameAs 2912398052 @default.
• W2912398052 citedByCount "0" @default.
• W2912398052 crossrefType "journal-article" @default.
• W2912398052 hasAuthorship W2912398052A5014986104 @default.
• W2912398052 hasBestOaLocation W29123980521 @default.
• W2912398052 hasConcept C105702510 @default.
• W2912398052 hasConcept C118552586 @default.
• W2912398052 hasConcept C126838900 @default.
• W2912398052 hasConcept C143409427 @default.
• W2912398052 hasConcept C15744967 @default.
• W2912398052 hasConcept C169760540 @default.
• W2912398052 hasConcept C2778013878 @default.
• W2912398052 hasConcept C2778609137 @default.
• W2912398052 hasConcept C2779857881 @default.
• W2912398052 hasConcept C2780640218 @default.
• W2912398052 hasConcept C2781192897 @default.
• W2912398052 hasConcept C529278444 @default.
• W2912398052 hasConcept C71924100 @default.
• W2912398052 hasConcept C84787856 @default.
• W2912398052 hasConceptScore W2912398052C105702510 @default.
• W2912398052 hasConceptScore W2912398052C118552586 @default.
• W2912398052 hasConceptScore W2912398052C126838900 @default.
• W2912398052 hasConceptScore W2912398052C143409427 @default.
• W2912398052 hasConceptScore W2912398052C15744967 @default.
• W2912398052 hasConceptScore W2912398052C169760540 @default.
• W2912398052 hasConceptScore W2912398052C2778013878 @default.
• W2912398052 hasConceptScore W2912398052C2778609137 @default.
• W2912398052 hasConceptScore W2912398052C2779857881 @default.
• W2912398052 hasConceptScore W2912398052C2780640218 @default.
• W2912398052 hasConceptScore W2912398052C2781192897 @default.
• W2912398052 hasConceptScore W2912398052C529278444 @default.
• W2912398052 hasConceptScore W2912398052C71924100 @default.
• W2912398052 hasConceptScore W2912398052C84787856 @default.
• W2912398052 hasIssue "1" @default.
• W2912398052 hasLocation W29123980521 @default.
• W2912398052 hasOpenAccess W2912398052 @default.
• W2912398052 hasPrimaryLocation W29123980521 @default.
• W2912398052 hasRelatedWork W1972438508 @default.
• W2912398052 hasRelatedWork W2043433309 @default.
• W2912398052 hasRelatedWork W2061813821 @default.
• W2912398052 hasRelatedWork W2151651656 @default.
• W2912398052 hasRelatedWork W2409075422 @default.
• W2912398052 hasRelatedWork W2779543750 @default.
• W2912398052 hasRelatedWork W2807766690 @default.
• W2912398052 hasRelatedWork W4255671330 @default.
• W2912398052 hasRelatedWork W2181663221 @default.
• W2912398052 hasRelatedWork W59224710 @default.
• W2912398052 hasVolume "19" @default.
• W2912398052 isParatext "false" @default.
• W2912398052 isRetracted "false" @default.
• W2912398052 magId "2912398052" @default.
• W2912398052 workType "article" @default.