FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912405129> ?p ?o ?g. }

• W2912405129 endingPage "3733" @default.
• W2912405129 startingPage "3720" @default.
• W2912405129 abstract "Among the different types of polymeric vehicles, (PLGA) is biodegradable and has emerged as promising tool for the delivery of cancer therapeutics. The salient features of PLGA micro carriers include prolonged circulation time, increased tumor localization and biodegradability and effectiveness of the therapeutics. We have synthesized PLGA microspheres where curcumin can be loaded and thereby increases its bioavailability. The cytotoxicity of curcumin (PLGA@CCM) microspheres was evaluated on triple negative breast cancer (TNBC) cell lines. They were found to induce apoptosis by perturbing the mitochondrial membrane potential. PLGA@CCM@FA induces apoptosis in human triple negative breast cancer cells by up-regulating Cleaved caspase-3 and down regutes p-AKT. The in-vivo study in BALB/C mice model exhibited more tumor regression in case of PLGA@CCM@FA microspheres. Our results suggests that these microspheres can be an effective vehicle for delivery of hydrophobic drugs to the folate over expressed cancer cells." @default.
• W2912405129 created "2019-02-21" @default.
• W2912405129 creator A5034212708 @default.
• W2912405129 creator A5036193481 @default.
• W2912405129 creator A5043499776 @default.
• W2912405129 creator A5054045080 @default.
• W2912405129 creator A5061517411 @default.
• W2912405129 creator A5062960149 @default.
• W2912405129 creator A5089943886 @default.
• W2912405129 creator A5090802552 @default.
• W2912405129 date "2019-07-01" @default.
• W2912405129 modified "2023-10-14" @default.
• W2912405129 title "An <i>In Vivo</i> Study for Targeted Delivery of Curcumin in Human Triple Negative Breast Carcinoma Cells Using Biocompatible PLGA Microspheres Conjugated with Folic Acid" @default.
• W2912405129 doi "https://doi.org/10.1166/jnn.2019.16292" @default.
• W2912405129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30764928" @default.
• W2912405129 hasPublicationYear "2019" @default.
• W2912405129 type Work @default.
• W2912405129 sameAs 2912405129 @default.
• W2912405129 citedByCount "15" @default.
• W2912405129 countsByYear W29124051292019 @default.
• W2912405129 countsByYear W29124051292020 @default.
• W2912405129 countsByYear W29124051292021 @default.
• W2912405129 countsByYear W29124051292022 @default.
• W2912405129 countsByYear W29124051292023 @default.
• W2912405129 crossrefType "journal-article" @default.
• W2912405129 hasAuthorship W2912405129A5034212708 @default.
• W2912405129 hasAuthorship W2912405129A5036193481 @default.
• W2912405129 hasAuthorship W2912405129A5043499776 @default.
• W2912405129 hasAuthorship W2912405129A5054045080 @default.
• W2912405129 hasAuthorship W2912405129A5061517411 @default.
• W2912405129 hasAuthorship W2912405129A5062960149 @default.
• W2912405129 hasAuthorship W2912405129A5089943886 @default.
• W2912405129 hasAuthorship W2912405129A5090802552 @default.
• W2912405129 hasConcept C112613896 @default.
• W2912405129 hasConcept C121608353 @default.
• W2912405129 hasConcept C126322002 @default.
• W2912405129 hasConcept C127413603 @default.
• W2912405129 hasConcept C1318750 @default.
• W2912405129 hasConcept C136229726 @default.
• W2912405129 hasConcept C150903083 @default.
• W2912405129 hasConcept C155672457 @default.
• W2912405129 hasConcept C159985019 @default.
• W2912405129 hasConcept C171250308 @default.
• W2912405129 hasConcept C189942447 @default.
• W2912405129 hasConcept C192562407 @default.
• W2912405129 hasConcept C207001950 @default.
• W2912405129 hasConcept C2778250585 @default.
• W2912405129 hasConcept C2780110267 @default.
• W2912405129 hasConcept C2780165375 @default.
• W2912405129 hasConcept C2992130864 @default.
• W2912405129 hasConcept C3018521938 @default.
• W2912405129 hasConcept C42360764 @default.
• W2912405129 hasConcept C502942594 @default.
• W2912405129 hasConcept C521977710 @default.
• W2912405129 hasConcept C530470458 @default.
• W2912405129 hasConcept C71924100 @default.
• W2912405129 hasConcept C86803240 @default.
• W2912405129 hasConcept C98274493 @default.
• W2912405129 hasConceptScore W2912405129C112613896 @default.
• W2912405129 hasConceptScore W2912405129C121608353 @default.
• W2912405129 hasConceptScore W2912405129C126322002 @default.
• W2912405129 hasConceptScore W2912405129C127413603 @default.
• W2912405129 hasConceptScore W2912405129C1318750 @default.
• W2912405129 hasConceptScore W2912405129C136229726 @default.
• W2912405129 hasConceptScore W2912405129C150903083 @default.
• W2912405129 hasConceptScore W2912405129C155672457 @default.
• W2912405129 hasConceptScore W2912405129C159985019 @default.
• W2912405129 hasConceptScore W2912405129C171250308 @default.
• W2912405129 hasConceptScore W2912405129C189942447 @default.
• W2912405129 hasConceptScore W2912405129C192562407 @default.
• W2912405129 hasConceptScore W2912405129C207001950 @default.
• W2912405129 hasConceptScore W2912405129C2778250585 @default.
• W2912405129 hasConceptScore W2912405129C2780110267 @default.
• W2912405129 hasConceptScore W2912405129C2780165375 @default.
• W2912405129 hasConceptScore W2912405129C2992130864 @default.
• W2912405129 hasConceptScore W2912405129C3018521938 @default.
• W2912405129 hasConceptScore W2912405129C42360764 @default.
• W2912405129 hasConceptScore W2912405129C502942594 @default.
• W2912405129 hasConceptScore W2912405129C521977710 @default.
• W2912405129 hasConceptScore W2912405129C530470458 @default.
• W2912405129 hasConceptScore W2912405129C71924100 @default.
• W2912405129 hasConceptScore W2912405129C86803240 @default.
• W2912405129 hasConceptScore W2912405129C98274493 @default.
• W2912405129 hasIssue "7" @default.
• W2912405129 hasLocation W29124051291 @default.
• W2912405129 hasOpenAccess W2912405129 @default.
• W2912405129 hasPrimaryLocation W29124051291 @default.
• W2912405129 hasRelatedWork W1945324269 @default.
• W2912405129 hasRelatedWork W2138709490 @default.
• W2912405129 hasRelatedWork W2161392596 @default.
• W2912405129 hasRelatedWork W2236292810 @default.
• W2912405129 hasRelatedWork W2388993849 @default.
• W2912405129 hasRelatedWork W2889184614 @default.
• W2912405129 hasRelatedWork W2974103503 @default.
• W2912405129 hasRelatedWork W3135738536 @default.
• W2912405129 hasRelatedWork W3163350643 @default.
• W2912405129 hasRelatedWork W4236735287 @default.
• W2912405129 hasVolume "19" @default.

• next