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• W2912405537 abstract "2-Phenylethanol (2-PE) is an important flavor ingredient with a rose-like odor. Due to concerns about the toxic byproducts potentially found in 2-PE from chemical synthesis, consumers prefer the natural aroma compound, promoting the biosynthesis of 2-PE. Various microorganisms produce 2-PE naturally with low yield. Recent metabolic engineering strategies in yeasts and Escherichia coli have achieved great success in improving 2-PE bioproduction, including the alleviation of feed-back inhibition, improvement of precursor transport, enhancing activities of crucial enzymes, and reduction of by-products. Here, we review the metabolic engineering strategies applied to microorganisms for increasing bioproduction of 2-PE, address current problems, and propose further improvements." @default.
• W2912405537 created "2019-02-21" @default.
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• W2912405537 date "2019-05-01" @default.
• W2912405537 modified "2023-10-14" @default.
• W2912405537 title "Advances in 2-phenylethanol production from engineered microorganisms" @default.
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• W2912405537 doi "https://doi.org/10.1016/j.biotechadv.2019.02.005" @default.
• W2912405537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30768954" @default.
• W2912405537 hasPublicationYear "2019" @default.
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