Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912405941> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2912405941 endingPage "S252" @default.
- W2912405941 startingPage "S251" @default.
- W2912405941 abstract "Chronic cold stress has long-term dramatic effects on the animal immune and neuroendocrine systems. As one of the important regions of the brain, the hippocampus is the main region involved in response to stressors. Nevertheless, the impact to the hippocampus following cold exposure and the underlying mechanism involved are not clear. To evaluate the response of the hippocampus during chronic cold stress, male C57BL/6 mice were exposed to 4 °C, 3 h per day for 1 week, after which neuroinflammation and the molecular and signaling pathways in the hippocampus response to cold stress were investigated. To confirm the potential mechanism, BV2 cells were treated with γ-aminobutyric acid (GABA) and BAY 11-7082 and MCC950, then the activation of microglia and key proteins involved in the regulation of inflammation were measured. We demonstrated that chronic cold stress induced the activation of microglia, the emergence of neuroinflammation, and the impairment of neurons in the hippocampus, which might be the result of GABA-mediated activation of nod-like receptor protein 3 (NLRP3) inflammasome and the nuclear factor kappa B (NF-κB) signaling pathway." @default.
- W2912405941 created "2019-02-21" @default.
- W2912405941 creator A5020658677 @default.
- W2912405941 creator A5021360243 @default.
- W2912405941 creator A5022670452 @default.
- W2912405941 creator A5060540666 @default.
- W2912405941 creator A5076173044 @default.
- W2912405941 date "2019-01-01" @default.
- W2912405941 modified "2023-10-14" @default.
- W2912405941 title "Effects of prenatal exposure to methylazoxymethanol acetate on juvenile social play behavior and ultrasonic communication in male and female rats" @default.
- W2912405941 doi "https://doi.org/10.1016/j.euroneuro.2018.11.399" @default.
- W2912405941 hasPublicationYear "2019" @default.
- W2912405941 type Work @default.
- W2912405941 sameAs 2912405941 @default.
- W2912405941 citedByCount "0" @default.
- W2912405941 crossrefType "journal-article" @default.
- W2912405941 hasAuthorship W2912405941A5020658677 @default.
- W2912405941 hasAuthorship W2912405941A5021360243 @default.
- W2912405941 hasAuthorship W2912405941A5022670452 @default.
- W2912405941 hasAuthorship W2912405941A5060540666 @default.
- W2912405941 hasAuthorship W2912405941A5076173044 @default.
- W2912405941 hasConcept C126322002 @default.
- W2912405941 hasConcept C134018914 @default.
- W2912405941 hasConcept C169760540 @default.
- W2912405941 hasConcept C170493617 @default.
- W2912405941 hasConcept C2776914184 @default.
- W2912405941 hasConcept C2777209026 @default.
- W2912405941 hasConcept C2779830541 @default.
- W2912405941 hasConcept C2781161787 @default.
- W2912405941 hasConcept C71924100 @default.
- W2912405941 hasConcept C86803240 @default.
- W2912405941 hasConcept C87753298 @default.
- W2912405941 hasConceptScore W2912405941C126322002 @default.
- W2912405941 hasConceptScore W2912405941C134018914 @default.
- W2912405941 hasConceptScore W2912405941C169760540 @default.
- W2912405941 hasConceptScore W2912405941C170493617 @default.
- W2912405941 hasConceptScore W2912405941C2776914184 @default.
- W2912405941 hasConceptScore W2912405941C2777209026 @default.
- W2912405941 hasConceptScore W2912405941C2779830541 @default.
- W2912405941 hasConceptScore W2912405941C2781161787 @default.
- W2912405941 hasConceptScore W2912405941C71924100 @default.
- W2912405941 hasConceptScore W2912405941C86803240 @default.
- W2912405941 hasConceptScore W2912405941C87753298 @default.
- W2912405941 hasLocation W29124059411 @default.
- W2912405941 hasOpenAccess W2912405941 @default.
- W2912405941 hasPrimaryLocation W29124059411 @default.
- W2912405941 hasRelatedWork W2735949591 @default.
- W2912405941 hasRelatedWork W2804482952 @default.
- W2912405941 hasRelatedWork W2964855216 @default.
- W2912405941 hasRelatedWork W2965616929 @default.
- W2912405941 hasRelatedWork W3096531136 @default.
- W2912405941 hasRelatedWork W3196858661 @default.
- W2912405941 hasRelatedWork W3214943155 @default.
- W2912405941 hasRelatedWork W4210549260 @default.
- W2912405941 hasRelatedWork W4289830533 @default.
- W2912405941 hasRelatedWork W4293561577 @default.
- W2912405941 hasVolume "29" @default.
- W2912405941 isParatext "false" @default.
- W2912405941 isRetracted "false" @default.
- W2912405941 magId "2912405941" @default.
- W2912405941 workType "article" @default.