FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912409264> ?p ?o ?g. }

• W2912409264 endingPage "347" @default.
• W2912409264 startingPage "339" @default.
• W2912409264 abstract "INTRODUCTION: Rectal indomethacin and topical spray of epinephrine have separately shown efficacy in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) in randomized controlled trials. We hypothesized that the combination of indomethacin and topical spray of epinephrine on the duodenal papillae would further reduce PEP than when indomethacin was used alone. Methods: We conducted a comparative effectiveness, multicenter, double-blinded, randomized trial of rectal indomethacin alone vs a combination of rectal indomethacin and topical spray of epinephrine for the prevention of PEP in high-risk patients. The primary outcome was the incidence of PEP and the secondary outcome was the severity of PEP. A 2-tailed Fisher's exact test was used to analyze the difference in the proportion of patients with PEP in the indomethacin alone vs the combination group. Results: A total of 960 patients (mean age 52.33 ± 14.96 years; 551 [57.4%] females) were randomized and 959 completed follow-up. The baseline demographic and clinical characteristics were similar between the 2 groups. Women <50 years of age (25.4%) and difficult cannulation (84.9%) were the most common PEP risk factors. The incidence of PEP was 6.4% in the indomethacin alone group (n = 482) compared to 6.7% in the combination group (n = 477; P = 0.87). Severe PEP was found in 5 (12%) and 7 (16%) patients in the indomethacin alone and combination groups, respectively (P = 0.88). The overall mortality was 0.6%, which was unrelated to the primary outcome. Conclusions: The combination of rectal indomethacin and topical spray of epinephrine does not reduce the incidence of PEP compared to rectal indomethacin alone in high-risk patients; https://clinicaltrials.gov/ct2/show/NCT02116309." @default.
• W2912409264 created "2019-02-21" @default.
• W2912409264 creator A5003430702 @default.
• W2912409264 creator A5017418894 @default.
• W2912409264 creator A5032847603 @default.
• W2912409264 creator A5034099238 @default.
• W2912409264 creator A5038843628 @default.
• W2912409264 creator A5041410733 @default.
• W2912409264 creator A5051721587 @default.
• W2912409264 creator A5054853416 @default.
• W2912409264 creator A5055033059 @default.
• W2912409264 creator A5063779181 @default.
• W2912409264 creator A5064304774 @default.
• W2912409264 creator A5066903532 @default.
• W2912409264 creator A5069787247 @default.
• W2912409264 creator A5072926655 @default.
• W2912409264 creator A5073670795 @default.
• W2912409264 creator A5075107428 @default.
• W2912409264 creator A5078585099 @default.
• W2912409264 creator A5084307882 @default.
• W2912409264 creator A5085267958 @default.
• W2912409264 date "2019-01-24" @default.
• W2912409264 modified "2023-09-29" @default.
• W2912409264 title "A Randomized Trial of Topical Epinephrine and Rectal Indomethacin for Preventing Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis in High-Risk Patients" @default.
• W2912409264 cites W1202277790 @default.
• W2912409264 cites W1888410836 @default.
• W2912409264 cites W1969964382 @default.
• W2912409264 cites W1972036508 @default.
• W2912409264 cites W1999720135 @default.
• W2912409264 cites W2003820603 @default.
• W2912409264 cites W2007359772 @default.
• W2912409264 cites W2024010127 @default.
• W2912409264 cites W2043813971 @default.
• W2912409264 cites W2067928535 @default.
• W2912409264 cites W2088123542 @default.
• W2912409264 cites W2089115083 @default.
• W2912409264 cites W2093274439 @default.
• W2912409264 cites W2093754043 @default.
• W2912409264 cites W2100650200 @default.
• W2912409264 cites W2103377881 @default.
• W2912409264 cites W2120931658 @default.
• W2912409264 cites W2147825364 @default.
• W2912409264 cites W2153111158 @default.
• W2912409264 cites W2515063166 @default.
• W2912409264 cites W2516880594 @default.
• W2912409264 cites W2519533902 @default.
• W2912409264 cites W2735448143 @default.
• W2912409264 doi "https://doi.org/10.14309/ajg.0000000000000049" @default.
• W2912409264 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30730860" @default.
• W2912409264 hasPublicationYear "2019" @default.
• W2912409264 type Work @default.
• W2912409264 sameAs 2912409264 @default.
• W2912409264 citedByCount "27" @default.
• W2912409264 countsByYear W29124092642019 @default.
• W2912409264 countsByYear W29124092642020 @default.
• W2912409264 countsByYear W29124092642021 @default.
• W2912409264 countsByYear W29124092642022 @default.
• W2912409264 countsByYear W29124092642023 @default.
• W2912409264 crossrefType "journal-article" @default.
• W2912409264 hasAuthorship W2912409264A5003430702 @default.
• W2912409264 hasAuthorship W2912409264A5017418894 @default.
• W2912409264 hasAuthorship W2912409264A5032847603 @default.
• W2912409264 hasAuthorship W2912409264A5034099238 @default.
• W2912409264 hasAuthorship W2912409264A5038843628 @default.
• W2912409264 hasAuthorship W2912409264A5041410733 @default.
• W2912409264 hasAuthorship W2912409264A5051721587 @default.
• W2912409264 hasAuthorship W2912409264A5054853416 @default.
• W2912409264 hasAuthorship W2912409264A5055033059 @default.
• W2912409264 hasAuthorship W2912409264A5063779181 @default.
• W2912409264 hasAuthorship W2912409264A5064304774 @default.
• W2912409264 hasAuthorship W2912409264A5066903532 @default.
• W2912409264 hasAuthorship W2912409264A5069787247 @default.
• W2912409264 hasAuthorship W2912409264A5072926655 @default.
• W2912409264 hasAuthorship W2912409264A5073670795 @default.
• W2912409264 hasAuthorship W2912409264A5075107428 @default.
• W2912409264 hasAuthorship W2912409264A5078585099 @default.
• W2912409264 hasAuthorship W2912409264A5084307882 @default.
• W2912409264 hasAuthorship W2912409264A5085267958 @default.
• W2912409264 hasConcept C120665830 @default.
• W2912409264 hasConcept C121332964 @default.
• W2912409264 hasConcept C126322002 @default.
• W2912409264 hasConcept C141071460 @default.
• W2912409264 hasConcept C168563851 @default.
• W2912409264 hasConcept C191093355 @default.
• W2912409264 hasConcept C2775859304 @default.
• W2912409264 hasConcept C2775967933 @default.
• W2912409264 hasConcept C2778444009 @default.
• W2912409264 hasConcept C42219234 @default.
• W2912409264 hasConcept C61511704 @default.
• W2912409264 hasConcept C71924100 @default.
• W2912409264 hasConcept C90924648 @default.
• W2912409264 hasConceptScore W2912409264C120665830 @default.
• W2912409264 hasConceptScore W2912409264C121332964 @default.
• W2912409264 hasConceptScore W2912409264C126322002 @default.
• W2912409264 hasConceptScore W2912409264C141071460 @default.
• W2912409264 hasConceptScore W2912409264C168563851 @default.
• W2912409264 hasConceptScore W2912409264C191093355 @default.
• W2912409264 hasConceptScore W2912409264C2775859304 @default.

• next