FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912427059> ?p ?o ?g. }

• W2912427059 endingPage "2974" @default.
• W2912427059 startingPage "2969" @default.
• W2912427059 abstract "Abstract The development of cancer and their response to radiation are intricately linked to the tumor microenvironment (TME) in which they reside. Tumor cells, immune cells, and stromal cells interact with each other and are influenced by the microbiome and metabolic state of the host, and these interactions are constantly evolving. Stromal cells not only secrete extracellular matrix and participate in wound contraction, but they also secrete fibroblast growth factors(FGF) molecules, which mediate macrophage differentiation. Tumor-associated macrophages migrate to hypoxic areas and secrete vascular endothelial growth factor (VEGF) to promote angiogenesis. The microbiome and its byproducts alter the metabolic milieu by shifting the balance between glucose utilization and fatty acid oxidation, and these changes subsequently influence the immune response in the TME. Not only does radiation exert cell-autonomous effects on tumor cells, but it influences both the tumor-promoting and tumor-suppressive components in the TME. To gain a deeper understanding of how the TME influences the response to radiation, the American Society for Radiation Oncology and the American Association of Cancer Research organized a scientific workshop on July 26–27, 2018, to discuss how the microbiome, the immune response, the metabolome, and the stroma all shift the balance between radiosensitivity and radioresistance. The proceedings from this workshop are discussed here and highlight recent discoveries in the field, as well as the most important areas for future research." @default.
• W2912427059 created "2019-02-21" @default.
• W2912427059 creator A5016731809 @default.
• W2912427059 creator A5020033657 @default.
• W2912427059 creator A5027276690 @default.
• W2912427059 creator A5043864498 @default.
• W2912427059 creator A5055292782 @default.
• W2912427059 creator A5080172191 @default.
• W2912427059 date "2019-05-15" @default.
• W2912427059 modified "2023-09-27" @default.
• W2912427059 title "Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO–AACR Research Workshop" @default.
• W2912427059 cites W1958497199 @default.
• W2912427059 cites W1980568044 @default.
• W2912427059 cites W1993686673 @default.
• W2912427059 cites W2016193552 @default.
• W2912427059 cites W2033556029 @default.
• W2912427059 cites W2039123767 @default.
• W2912427059 cites W2049553585 @default.
• W2912427059 cites W2117878645 @default.
• W2912427059 cites W2169115903 @default.
• W2912427059 cites W2185075416 @default.
• W2912427059 cites W2317488978 @default.
• W2912427059 cites W2344855029 @default.
• W2912427059 cites W2516006542 @default.
• W2912427059 cites W2528386527 @default.
• W2912427059 cites W2531786193 @default.
• W2912427059 cites W2560367415 @default.
• W2912427059 cites W2563663251 @default.
• W2912427059 cites W2566424620 @default.
• W2912427059 cites W2578528809 @default.
• W2912427059 cites W2580288809 @default.
• W2912427059 cites W2592120828 @default.
• W2912427059 cites W2624275086 @default.
• W2912427059 cites W2727463864 @default.
• W2912427059 cites W2765314233 @default.
• W2912427059 cites W2766903152 @default.
• W2912427059 cites W2775006908 @default.
• W2912427059 cites W2777385100 @default.
• W2912427059 cites W2782333299 @default.
• W2912427059 cites W2783641815 @default.
• W2912427059 cites W2788846482 @default.
• W2912427059 cites W2795993993 @default.
• W2912427059 cites W2806268945 @default.
• W2912427059 cites W2808657188 @default.
• W2912427059 cites W2883374225 @default.
• W2912427059 cites W2888346100 @default.
• W2912427059 cites W2893814357 @default.
• W2912427059 doi "https://doi.org/10.1158/1078-0432.ccr-18-3781" @default.
• W2912427059 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7265991" @default.
• W2912427059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30723144" @default.
• W2912427059 hasPublicationYear "2019" @default.
• W2912427059 type Work @default.
• W2912427059 sameAs 2912427059 @default.
• W2912427059 citedByCount "22" @default.
• W2912427059 countsByYear W29124270592019 @default.
• W2912427059 countsByYear W29124270592020 @default.
• W2912427059 countsByYear W29124270592021 @default.
• W2912427059 countsByYear W29124270592022 @default.
• W2912427059 countsByYear W29124270592023 @default.
• W2912427059 crossrefType "journal-article" @default.
• W2912427059 hasAuthorship W2912427059A5016731809 @default.
• W2912427059 hasAuthorship W2912427059A5020033657 @default.
• W2912427059 hasAuthorship W2912427059A5027276690 @default.
• W2912427059 hasAuthorship W2912427059A5043864498 @default.
• W2912427059 hasAuthorship W2912427059A5055292782 @default.
• W2912427059 hasAuthorship W2912427059A5080172191 @default.
• W2912427059 hasBestOaLocation W29124270591 @default.
• W2912427059 hasConcept C121608353 @default.
• W2912427059 hasConcept C126322002 @default.
• W2912427059 hasConcept C134018914 @default.
• W2912427059 hasConcept C143121216 @default.
• W2912427059 hasConcept C16930146 @default.
• W2912427059 hasConcept C203014093 @default.
• W2912427059 hasConcept C2776107976 @default.
• W2912427059 hasConcept C2780394083 @default.
• W2912427059 hasConcept C2909706936 @default.
• W2912427059 hasConcept C49039625 @default.
• W2912427059 hasConcept C502942594 @default.
• W2912427059 hasConcept C509974204 @default.
• W2912427059 hasConcept C54355233 @default.
• W2912427059 hasConcept C58962609 @default.
• W2912427059 hasConcept C60644358 @default.
• W2912427059 hasConcept C71924100 @default.
• W2912427059 hasConcept C86803240 @default.
• W2912427059 hasConcept C8891405 @default.
• W2912427059 hasConcept C96232424 @default.
• W2912427059 hasConceptScore W2912427059C121608353 @default.
• W2912427059 hasConceptScore W2912427059C126322002 @default.
• W2912427059 hasConceptScore W2912427059C134018914 @default.
• W2912427059 hasConceptScore W2912427059C143121216 @default.
• W2912427059 hasConceptScore W2912427059C16930146 @default.
• W2912427059 hasConceptScore W2912427059C203014093 @default.
• W2912427059 hasConceptScore W2912427059C2776107976 @default.
• W2912427059 hasConceptScore W2912427059C2780394083 @default.
• W2912427059 hasConceptScore W2912427059C2909706936 @default.
• W2912427059 hasConceptScore W2912427059C49039625 @default.
• W2912427059 hasConceptScore W2912427059C502942594 @default.
• W2912427059 hasConceptScore W2912427059C509974204 @default.

• next