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- W2912451901 abstract "Aims The purpose of this study was to assess the markers for type 2 diabetes (T2D) in association with duration of breastfeeding in the Peri/ postnatal Epigenetic Twins Study (PETS). Methods Cross-sectional research study of children 6-7 years of age participating in the PETS (n=94). To investigate the relationship between duration of breastfeeding and T2D markers (insulin and Homeostasis Model Assessment Insulin Resistance levels [HOMA2-IR]). Results Infants breastfed for more than 4 months had significantly lower mean insulin levels (22.8 pmol/L; 95% confidence interval [CI], 4.05-22.0, P=0.005) and significantly lower mean HOMA2-IR levels (0.41; 95% CI, 0.07-0.40, P=0.005) than the infants breastfed for less than 4 months. Conclusions Breastfeeding for more than 4 months protects against the risk of developing insulin resistance associated with the development of T2D in the PETS children, supporting the idea that T2D may be partially programmed by nutrition in early life. Understanding the interactions of nutrition with our epigenome may allow healthcare providers to tailor education and interventions focused on early life nutritional habits to prevent T2D." @default.
- W2912451901 created "2019-02-21" @default.
- W2912451901 creator A5016490837 @default.
- W2912451901 date "2019-01-01" @default.
- W2912451901 modified "2023-09-25" @default.
- W2912451901 title "Breastfeeding reduces risk of Type 2 Diabetes in the (PETS)" @default.
- W2912451901 doi "https://doi.org/10.1016/j.outlook.2018.12.026" @default.
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