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- W2912452478 abstract "Purpose: Pneumatosis Intestinalis (PI) is a well recognized manifestation of necrotizing enterocolitis in neonates. Rarely seen beyond newborn period, PI has been reported in adults with connective tissue disorders, pulmonary, infectious and gastrointestinal diseases. We present a 15 year old girl with diagnosis of gastric Crohn's disease who developed sudden onset severe abdominal pain. She was diagnosed with Crohn's disease at 11 years of age and treated with steroids and 6-Mercaptopurine (6-MP). She was weaned of her medications after 2 years when she had normal histology on her endoscopic evaluation. Four years later, at the time of presentation, she was on acid-blocker treatment. She had severe right lower and right upper quadrant pain with no fever, diarrhea or vomiting. She had diffuse tenderness with guarding and rebound. Her abdominal CAT scan showed multiple collections of intramural air within the walls of distal ileum and right colon. Because of persistent pain and rebound on exam, she underwent laparoscopic exploration. Blebs on the serosal surface of the terminal ileum were recognized as PI with no other abnormal finding requiring surgical intervention. She was started on steroids and immunomodulator therapy with resolution of her symptoms. There was no evidence of PI on repeated abdominal CAT scan in 2 weeks. She underwent endoscopic evaluation which showed active ileitis with normal colonic histology. Conclusion: Although rare outside the neonatal period, PI can be a finding in patients with acute exacerbation of inflammatory bowel disease. In the absence of complications requiring surgical exploration, PI in a child with inflammatory bowel disease should be treated with anti-inflammatory therapy." @default.
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- W2912452478 date "2007-09-01" @default.
- W2912452478 modified "2023-09-25" @default.
- W2912452478 title "Pneumatosis Intestinalis: Rare Presentation of Crohnʼs Disease Exacerbation" @default.
- W2912452478 doi "https://doi.org/10.14309/00000434-200709002-01182" @default.
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