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• W2912452740 startingPage "29" @default.
• W2912452740 abstract "There are multiple proinflammatory pathways in the pathogenesis of asthma. These include both innate and adaptive inflammation, in addition to inflammatory and physiologic responses mediated by eicosanoids . An important component of the innate allergic immune response is ILC2 activated by interleukin (IL)-33, thymic stromal lymphopoietin , and IL-25 to produce IL-5 and IL-13. In terms of the adaptive T-lymphocyte immunity, CD4+ Th2 and IL-17–producing cells are critical in the inflammatory responses in asthma. Last, eicosanoids involved in asthma pathogenesis include prostaglandin D 2 and the cysteinyl leukotrienes that promote smooth muscle constriction and inflammation that propagate allergic responses." @default.
• W2912452740 created "2019-02-21" @default.
• W2912452740 creator A5067422163 @default.
• W2912452740 creator A5080558064 @default.
• W2912452740 date "2019-03-01" @default.
• W2912452740 modified "2023-10-08" @default.
• W2912452740 title "Proinflammatory Pathways in the Pathogenesis of Asthma" @default.
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