FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912461490> ?p ?o ?g. }

• W2912461490 endingPage "100147" @default.
• W2912461490 startingPage "100147" @default.
• W2912461490 abstract "Prolonged or repeated exposure to stress increases risk for a variety of psychological disorders, many of which are marked by dysfunction of corticolimbic brain regions. Notably, women are more likely than men to be diagnosed with these disorders, especially when onset of symptoms follows stressful life events. Using rodent models, investigators have recently begun to elucidate sex-specific changes in the brain and behavior that occur immediately following chronic stress. However, little is known regarding the lasting sequelae of chronic stress, as well as how potential changes may impact responsivity to future stressors. We recently demonstrated that male and female rats show different patterns of dendritic reorganization in medial prefrontal cortex in the days following chronic stress. Here, we examined the immediate and lasting effects of chronic restraint stress (CRS; 3 h/day, 10 days) on neuronal activation, across several corticolimbic brain regions, induced by novel acute stress exposure. Chronically stressed male and female rats were exposed to acute elevated platform stress (EPS) either 1 (CRS-EPS) or 7 (CRS-Rest-EPS) days after CRS. Compared to rats exposed to EPS only, significant reductions in acute stress-induced c-Fos expression were observed in the medial prefrontal cortex, hippocampus, and paraventricular nucleus of the hypothalamus (PVN) in CRS-EPS male rats, some of which persisted to 7 days post-stress. In contrast, we found little modulation of novel stress-induced c-Fos expression in CRS-EPS female rats. However, CRS-Rest-EPS female rats exhibited a significant enhancement of acute stress-induced neuronal activity in the PVN. Together, these data show that prior chronic stress produces sex- and region-specific alterations in novel stress-induced neuronal activation, which are dependent on the presence or absence of a rest period following chronic stress. These findings suggest that the post-stress rest period may give rise to sex-specific neuroadaptations to stress, which may underlie sex differences in stress susceptibility versus resilience." @default.
• W2912461490 created "2019-02-21" @default.
• W2912461490 creator A5009307793 @default.
• W2912461490 creator A5024077621 @default.
• W2912461490 creator A5072780935 @default.
• W2912461490 date "2019-02-01" @default.
• W2912461490 modified "2023-10-14" @default.
• W2912461490 title "Chronic stress produces enduring sex- and region-specific alterations in novel stress-induced c-Fos expression" @default.
• W2912461490 cites W1510964369 @default.
• W2912461490 cites W1535894955 @default.
• W2912461490 cites W1698044858 @default.
• W2912461490 cites W1784991500 @default.
• W2912461490 cites W1966656140 @default.
• W2912461490 cites W1967097853 @default.
• W2912461490 cites W1968864595 @default.
• W2912461490 cites W1972276830 @default.
• W2912461490 cites W1979563893 @default.
• W2912461490 cites W1982114694 @default.
• W2912461490 cites W1982839897 @default.
• W2912461490 cites W1987261356 @default.
• W2912461490 cites W1989440992 @default.
• W2912461490 cites W1989957924 @default.
• W2912461490 cites W1994253126 @default.
• W2912461490 cites W1996396637 @default.
• W2912461490 cites W2001567401 @default.
• W2912461490 cites W2005084361 @default.
• W2912461490 cites W2005615207 @default.
• W2912461490 cites W2006050677 @default.
• W2912461490 cites W2009955389 @default.
• W2912461490 cites W2014570372 @default.
• W2912461490 cites W2016117011 @default.
• W2912461490 cites W2017186261 @default.
• W2912461490 cites W2018782871 @default.
• W2912461490 cites W2031955709 @default.
• W2912461490 cites W2037327301 @default.
• W2912461490 cites W2037749209 @default.
• W2912461490 cites W2040937137 @default.
• W2912461490 cites W2045447297 @default.
• W2912461490 cites W2050381565 @default.
• W2912461490 cites W2057462574 @default.
• W2912461490 cites W2070857586 @default.
• W2912461490 cites W2074033866 @default.
• W2912461490 cites W2078455464 @default.
• W2912461490 cites W2079927878 @default.
• W2912461490 cites W2083203013 @default.
• W2912461490 cites W2104281927 @default.
• W2912461490 cites W2113167245 @default.
• W2912461490 cites W2122384242 @default.
• W2912461490 cites W2123054324 @default.
• W2912461490 cites W2124065316 @default.
• W2912461490 cites W2127722821 @default.
• W2912461490 cites W2136403062 @default.
• W2912461490 cites W2137296158 @default.
• W2912461490 cites W2150037324 @default.
• W2912461490 cites W2152614652 @default.
• W2912461490 cites W2155922104 @default.
• W2912461490 cites W2164012002 @default.
• W2912461490 cites W2164670684 @default.
• W2912461490 cites W2166370054 @default.
• W2912461490 cites W2317480464 @default.
• W2912461490 cites W2463109632 @default.
• W2912461490 cites W2515820045 @default.
• W2912461490 cites W2586907386 @default.
• W2912461490 cites W2607032498 @default.
• W2912461490 cites W2623963505 @default.
• W2912461490 cites W2774139749 @default.
• W2912461490 cites W2789399653 @default.
• W2912461490 cites W4231738588 @default.
• W2912461490 cites W4319425380 @default.
• W2912461490 doi "https://doi.org/10.1016/j.ynstr.2019.100147" @default.
• W2912461490 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6430515" @default.
• W2912461490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30937353" @default.
• W2912461490 hasPublicationYear "2019" @default.
• W2912461490 type Work @default.
• W2912461490 sameAs 2912461490 @default.
• W2912461490 citedByCount "33" @default.
• W2912461490 countsByYear W29124614902019 @default.
• W2912461490 countsByYear W29124614902020 @default.
• W2912461490 countsByYear W29124614902021 @default.
• W2912461490 countsByYear W29124614902022 @default.
• W2912461490 countsByYear W29124614902023 @default.
• W2912461490 crossrefType "journal-article" @default.
• W2912461490 hasAuthorship W2912461490A5009307793 @default.
• W2912461490 hasAuthorship W2912461490A5024077621 @default.
• W2912461490 hasAuthorship W2912461490A5072780935 @default.
• W2912461490 hasBestOaLocation W29124614901 @default.
• W2912461490 hasConcept C104317684 @default.
• W2912461490 hasConcept C125370674 @default.
• W2912461490 hasConcept C126322002 @default.
• W2912461490 hasConcept C134018914 @default.
• W2912461490 hasConcept C150194340 @default.
• W2912461490 hasConcept C15744967 @default.
• W2912461490 hasConcept C169760540 @default.
• W2912461490 hasConcept C169900460 @default.
• W2912461490 hasConcept C2777003273 @default.
• W2912461490 hasConcept C2778654844 @default.
• W2912461490 hasConcept C2780323455 @default.
• W2912461490 hasConcept C2781161787 @default.

• next