FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912472242> ?p ?o ?g. }

• W2912472242 endingPage "849" @default.
• W2912472242 startingPage "844" @default.
• W2912472242 abstract "Background Antegrade cerebral perfusion (ACP) is an essential adjunct for prolonged hypothermic circulatory arrest (HCA) during aortic arch surgery. However, it has yet to be established whether ACP should be delivered unilaterally or bilaterally. The aim of the present meta-analysis is to investigate outcomes of unilateral ACP (uACP) compared to bilateral ACP (bACP) in comparative studies. Methods Electronic searches were performed using four databases from their inception to February 2017. Relevant comparative studies with adult patients who underwent aortic arch surgery using unilateral or bilateral ACP were included. Data was extracted by two independent researchers and analysed according to predefined endpoints using a random-effects model. Meta-regression was used to identify predictors of primary outcomes. Results Nine comparative studies were identified, comprising 967 uACP patients and 879 bACP patients. No significant differences in age, sex, or proportion of total arch replacements were identified. The uACP cohort had a greater proportion of acute dissections (86% vs 75%, p = 0.04). Hypothermic circulatory arrest and cerebral perfusion times were similar between both groups. No significant differences were seen between unilateral and bilateral groups in terms of mortality (odds ratio [OR] 0.97; 95% confidence interval [CI] 0.64–1.48; p = 0.90; I2 = 0%), permanent neurological deficit (PND) (OR 1.04; 95% CI 0.74–1.45; p = 0.85; I2 = 0%), temporary neurological deficit (p = 0.74), acute kidney injury (p = 0.36) or reoperation for bleeding (p = 0.65). No factors affecting mortality or PND were identified on meta-regression. Conclusion For patients undergoing aortic arch surgery, the available evidence supports either uACP or bACP as an adjunct to HCA. However, there is insufficient comparative evidence available to determine the benefit of either modalities in patients with longer durations of circulatory arrest. Antegrade cerebral perfusion (ACP) is an essential adjunct for prolonged hypothermic circulatory arrest (HCA) during aortic arch surgery. However, it has yet to be established whether ACP should be delivered unilaterally or bilaterally. The aim of the present meta-analysis is to investigate outcomes of unilateral ACP (uACP) compared to bilateral ACP (bACP) in comparative studies. Electronic searches were performed using four databases from their inception to February 2017. Relevant comparative studies with adult patients who underwent aortic arch surgery using unilateral or bilateral ACP were included. Data was extracted by two independent researchers and analysed according to predefined endpoints using a random-effects model. Meta-regression was used to identify predictors of primary outcomes. Nine comparative studies were identified, comprising 967 uACP patients and 879 bACP patients. No significant differences in age, sex, or proportion of total arch replacements were identified. The uACP cohort had a greater proportion of acute dissections (86% vs 75%, p = 0.04). Hypothermic circulatory arrest and cerebral perfusion times were similar between both groups. No significant differences were seen between unilateral and bilateral groups in terms of mortality (odds ratio [OR] 0.97; 95% confidence interval [CI] 0.64–1.48; p = 0.90; I2 = 0%), permanent neurological deficit (PND) (OR 1.04; 95% CI 0.74–1.45; p = 0.85; I2 = 0%), temporary neurological deficit (p = 0.74), acute kidney injury (p = 0.36) or reoperation for bleeding (p = 0.65). No factors affecting mortality or PND were identified on meta-regression. For patients undergoing aortic arch surgery, the available evidence supports either uACP or bACP as an adjunct to HCA. However, there is insufficient comparative evidence available to determine the benefit of either modalities in patients with longer durations of circulatory arrest." @default.
• W2912472242 created "2019-02-21" @default.
• W2912472242 creator A5015456000 @default.
• W2912472242 creator A5026801437 @default.
• W2912472242 creator A5033468770 @default.
• W2912472242 creator A5057285924 @default.
• W2912472242 creator A5057306885 @default.
• W2912472242 creator A5068947895 @default.
• W2912472242 date "2019-06-01" @default.
• W2912472242 modified "2023-09-25" @default.
• W2912472242 title "Unilateral Versus Bilateral Antegrade Cerebral Perfusion: A Meta-Analysis of Comparative Studies" @default.
• W2912472242 cites W1964435302 @default.
• W2912472242 cites W1965134223 @default.
• W2912472242 cites W1989699942 @default.
• W2912472242 cites W1990080158 @default.
• W2912472242 cites W1996739142 @default.
• W2912472242 cites W1996899584 @default.
• W2912472242 cites W2020305348 @default.
• W2912472242 cites W2026758688 @default.
• W2912472242 cites W2029162980 @default.
• W2912472242 cites W2063297627 @default.
• W2912472242 cites W2097507224 @default.
• W2912472242 cites W2115032840 @default.
• W2912472242 cites W2119287837 @default.
• W2912472242 cites W2128579427 @default.
• W2912472242 cites W2145521241 @default.
• W2912472242 cites W2157806886 @default.
• W2912472242 cites W2157823046 @default.
• W2912472242 cites W2160915729 @default.
• W2912472242 cites W2541967817 @default.
• W2912472242 cites W2581061491 @default.
• W2912472242 doi "https://doi.org/10.1016/j.hlc.2019.01.010" @default.
• W2912472242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30773323" @default.
• W2912472242 hasPublicationYear "2019" @default.
• W2912472242 type Work @default.
• W2912472242 sameAs 2912472242 @default.
• W2912472242 citedByCount "15" @default.
• W2912472242 countsByYear W29124722422020 @default.
• W2912472242 countsByYear W29124722422021 @default.
• W2912472242 countsByYear W29124722422022 @default.
• W2912472242 countsByYear W29124722422023 @default.
• W2912472242 crossrefType "journal-article" @default.
• W2912472242 hasAuthorship W2912472242A5015456000 @default.
• W2912472242 hasAuthorship W2912472242A5026801437 @default.
• W2912472242 hasAuthorship W2912472242A5033468770 @default.
• W2912472242 hasAuthorship W2912472242A5057285924 @default.
• W2912472242 hasAuthorship W2912472242A5057306885 @default.
• W2912472242 hasAuthorship W2912472242A5068947895 @default.
• W2912472242 hasConcept C126322002 @default.
• W2912472242 hasConcept C141071460 @default.
• W2912472242 hasConcept C146957229 @default.
• W2912472242 hasConcept C154281038 @default.
• W2912472242 hasConcept C156957248 @default.
• W2912472242 hasConcept C164705383 @default.
• W2912472242 hasConcept C2779980429 @default.
• W2912472242 hasConcept C2780631194 @default.
• W2912472242 hasConcept C2781285907 @default.
• W2912472242 hasConcept C42219234 @default.
• W2912472242 hasConcept C44249647 @default.
• W2912472242 hasConcept C71924100 @default.
• W2912472242 hasConcept C72859922 @default.
• W2912472242 hasConcept C95190672 @default.
• W2912472242 hasConceptScore W2912472242C126322002 @default.
• W2912472242 hasConceptScore W2912472242C141071460 @default.
• W2912472242 hasConceptScore W2912472242C146957229 @default.
• W2912472242 hasConceptScore W2912472242C154281038 @default.
• W2912472242 hasConceptScore W2912472242C156957248 @default.
• W2912472242 hasConceptScore W2912472242C164705383 @default.
• W2912472242 hasConceptScore W2912472242C2779980429 @default.
• W2912472242 hasConceptScore W2912472242C2780631194 @default.
• W2912472242 hasConceptScore W2912472242C2781285907 @default.
• W2912472242 hasConceptScore W2912472242C42219234 @default.
• W2912472242 hasConceptScore W2912472242C44249647 @default.
• W2912472242 hasConceptScore W2912472242C71924100 @default.
• W2912472242 hasConceptScore W2912472242C72859922 @default.
• W2912472242 hasConceptScore W2912472242C95190672 @default.
• W2912472242 hasIssue "6" @default.
• W2912472242 hasLocation W29124722421 @default.
• W2912472242 hasLocation W29124722422 @default.
• W2912472242 hasOpenAccess W2912472242 @default.
• W2912472242 hasPrimaryLocation W29124722421 @default.
• W2912472242 hasRelatedWork W1965324546 @default.
• W2912472242 hasRelatedWork W2039587263 @default.
• W2912472242 hasRelatedWork W2056316523 @default.
• W2912472242 hasRelatedWork W2133858085 @default.
• W2912472242 hasRelatedWork W2157981180 @default.
• W2912472242 hasRelatedWork W2335452761 @default.
• W2912472242 hasRelatedWork W2769022457 @default.
• W2912472242 hasRelatedWork W2793277235 @default.
• W2912472242 hasRelatedWork W3029343847 @default.
• W2912472242 hasRelatedWork W4288051280 @default.
• W2912472242 hasVolume "28" @default.
• W2912472242 isParatext "false" @default.
• W2912472242 isRetracted "false" @default.
• W2912472242 magId "2912472242" @default.
• W2912472242 workType "article" @default.