Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912477317> ?p ?o ?g. }
- W2912477317 endingPage "135" @default.
- W2912477317 startingPage "125" @default.
- W2912477317 abstract "A selectively antimycobacterial compound belonging to the nitrofuran class of antimicrobials has been developed via conjugation of the nitrofuran moiety to a series of spirocyclic piperidines through an amide linkage. It proved to have comparable activity against drug-sensitive (H37Rv) strain as well as multidrug-resistant, patient-derived strains of Mycobacterium tuberculosis. The compound is druglike, showed no appreciable cytotoxicity toward human retinal pigment epithelial cell line ARPE-19 in concentrations up to 100 μM and displayed low toxicity when evaluated in mice." @default.
- W2912477317 created "2019-02-21" @default.
- W2912477317 creator A5007339280 @default.
- W2912477317 creator A5024132763 @default.
- W2912477317 creator A5029661578 @default.
- W2912477317 creator A5043908129 @default.
- W2912477317 creator A5049341154 @default.
- W2912477317 creator A5049458503 @default.
- W2912477317 creator A5050225620 @default.
- W2912477317 creator A5057267104 @default.
- W2912477317 creator A5065956167 @default.
- W2912477317 creator A5068847009 @default.
- W2912477317 creator A5073129203 @default.
- W2912477317 creator A5076478999 @default.
- W2912477317 creator A5087571159 @default.
- W2912477317 date "2019-03-01" @default.
- W2912477317 modified "2023-10-13" @default.
- W2912477317 title "Attachment of a 5-nitrofuroyl moiety to spirocyclic piperidines produces non-toxic nitrofurans that are efficacious in vitro against multidrug-resistant Mycobacterium tuberculosis" @default.
- W2912477317 cites W1538374398 @default.
- W2912477317 cites W1761015360 @default.
- W2912477317 cites W1963457120 @default.
- W2912477317 cites W1964887576 @default.
- W2912477317 cites W2010973115 @default.
- W2912477317 cites W2024674972 @default.
- W2912477317 cites W2029526231 @default.
- W2912477317 cites W2035441482 @default.
- W2912477317 cites W2039634792 @default.
- W2912477317 cites W2047393488 @default.
- W2912477317 cites W2049383029 @default.
- W2912477317 cites W2067948745 @default.
- W2912477317 cites W2076498419 @default.
- W2912477317 cites W2081183202 @default.
- W2912477317 cites W2091356402 @default.
- W2912477317 cites W2098793988 @default.
- W2912477317 cites W2120027073 @default.
- W2912477317 cites W2135732933 @default.
- W2912477317 cites W2136931384 @default.
- W2912477317 cites W2140313556 @default.
- W2912477317 cites W2143113259 @default.
- W2912477317 cites W2148206106 @default.
- W2912477317 cites W2148886002 @default.
- W2912477317 cites W2156630451 @default.
- W2912477317 cites W2269784617 @default.
- W2912477317 cites W2322777826 @default.
- W2912477317 cites W2462331758 @default.
- W2912477317 cites W2512784686 @default.
- W2912477317 cites W2542913826 @default.
- W2912477317 cites W2585398968 @default.
- W2912477317 cites W2595267236 @default.
- W2912477317 cites W2951211106 @default.
- W2912477317 cites W4232256015 @default.
- W2912477317 doi "https://doi.org/10.1016/j.ejmech.2019.01.050" @default.
- W2912477317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30703656" @default.
- W2912477317 hasPublicationYear "2019" @default.
- W2912477317 type Work @default.
- W2912477317 sameAs 2912477317 @default.
- W2912477317 citedByCount "18" @default.
- W2912477317 countsByYear W29124773172019 @default.
- W2912477317 countsByYear W29124773172020 @default.
- W2912477317 countsByYear W29124773172021 @default.
- W2912477317 countsByYear W29124773172022 @default.
- W2912477317 countsByYear W29124773172023 @default.
- W2912477317 crossrefType "journal-article" @default.
- W2912477317 hasAuthorship W2912477317A5007339280 @default.
- W2912477317 hasAuthorship W2912477317A5024132763 @default.
- W2912477317 hasAuthorship W2912477317A5029661578 @default.
- W2912477317 hasAuthorship W2912477317A5043908129 @default.
- W2912477317 hasAuthorship W2912477317A5049341154 @default.
- W2912477317 hasAuthorship W2912477317A5049458503 @default.
- W2912477317 hasAuthorship W2912477317A5050225620 @default.
- W2912477317 hasAuthorship W2912477317A5057267104 @default.
- W2912477317 hasAuthorship W2912477317A5065956167 @default.
- W2912477317 hasAuthorship W2912477317A5068847009 @default.
- W2912477317 hasAuthorship W2912477317A5073129203 @default.
- W2912477317 hasAuthorship W2912477317A5076478999 @default.
- W2912477317 hasAuthorship W2912477317A5087571159 @default.
- W2912477317 hasConcept C109316439 @default.
- W2912477317 hasConcept C133936738 @default.
- W2912477317 hasConcept C142724271 @default.
- W2912477317 hasConcept C185592680 @default.
- W2912477317 hasConcept C202751555 @default.
- W2912477317 hasConcept C2776568683 @default.
- W2912477317 hasConcept C2776955177 @default.
- W2912477317 hasConcept C2777975735 @default.
- W2912477317 hasConcept C2778439535 @default.
- W2912477317 hasConcept C2779685592 @default.
- W2912477317 hasConcept C2781069245 @default.
- W2912477317 hasConcept C501593827 @default.
- W2912477317 hasConcept C54355233 @default.
- W2912477317 hasConcept C55493867 @default.
- W2912477317 hasConcept C71240020 @default.
- W2912477317 hasConcept C71924100 @default.
- W2912477317 hasConcept C86803240 @default.
- W2912477317 hasConcept C89423630 @default.
- W2912477317 hasConcept C98274493 @default.
- W2912477317 hasConceptScore W2912477317C109316439 @default.
- W2912477317 hasConceptScore W2912477317C133936738 @default.
- W2912477317 hasConceptScore W2912477317C142724271 @default.