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- W2912490271 endingPage "1383" @default.
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- W2912490271 abstract "A novel supramolecular multivalent glycosidase inhibitor was constructed based on the amphiphilic deoxynojirimycin derivative FA-DNJ. FA-DNJ self-assembled into spherical assemblies with the diameters between 103 nm and 137 nm under different pH values (pH 2-7) and showed a potent glycosidase effect against α-mannosidase with a Ki value of 0.11 μM, an effect that increased approximately 330-fold compared with that of miglitol. In addition, FA-DNJ exhibited a hypoglycaemic effect in mice." @default.
- W2912490271 created "2019-02-21" @default.
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- W2912490271 date "2019-01-01" @default.
- W2912490271 modified "2023-10-13" @default.
- W2912490271 title "Supramolecular azasugar clusters based on an amphiphilic fatty-acid-deoxynojirimycin derivative as multivalent glycosidase inhibitors" @default.
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- W2912490271 doi "https://doi.org/10.1039/c8tb03249a" @default.
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