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• W2912491875 abstract "BackgroundAllergic rhinitis is the main symptom of pollinosis, relieved by non-specific treatment universally. This study aimed to find the changes of serum metabolites between the seizure and remission periods of pollinosis and provide assistance in the diagnosis and/or therapy.MethodsMetabonomics based on 1H nuclear magnetic resonance (NMR) was used to study the 37 serum samples of pollinosis patients.ResultsWe believed that the decreased levels of isoleutine, leutine, valine, 3-hydroxybutyric acid, allo-threonine, alanine, methionine, glutamine, lysine, glycine, l-tyrosine, histidine, phenylalanine, lactate, acetate, O-acetylcholine, creatine and creatinine and the increased level of N-acetylglutamine at the seizure stage were statistically significant.ConclusionsPollinosis could change the metabolic profiles of energy, amino acid and lipid in patients, which might be the diagnosis and/or prognosis markers for hay fever patients." @default.
• W2912491875 created "2019-02-21" @default.
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• W2912491875 date "2019-01-01" @default.
• W2912491875 modified "2023-10-15" @default.
• W2912491875 title "1H NMR-based metabolomic study of metabolic profiling for pollinosis" @default.
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• W2912491875 doi "https://doi.org/10.1016/j.waojou.2018.11.005" @default.
• W2912491875 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6439407" @default.
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