FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912497171> ?p ?o ?g. }

• W2912497171 abstract "Nowadays, the need for the analysis of biological cells has become a platform for researchers to develop related technologies and devices for conducting appropriate manipulation such as trapping, screening, and sorting. This is because the analysis of biological cells can be beneficial to better understand the properties of biological cells and find the solution and treatment in medical applications. Various manipulation techniques have been developed to manipulate biological cells such as manipulation technique in chemical, mechanical, acoustic and electric fields. The DEP was force used to manipulate the cells resulting from the generation of a non-uniform AC electric field and electrode patterns play a major role in producing the required electric field. The current design has limitations in terms of the distribution pattern of the electric field generated and insufficient simulation data required for the development of biochip. There were two new electrodes which are ring pattern microelectrode and ripple pattern microelectrode developed in this study. The main objective of this work is to investigate the electric field distribution resulted from the microelectrodes. All analyses performed in this study were based on simulations. Simulations were carried out by using COMSOL Multiphysics software, which provides suitable simulation and analysis platform for this study. The optimisation of an electrode was done by making some modifications to the dimensions of the electrodes and simulated with different electrical potential values. This was done to improve the performance of the electrodes to trap a single cell. Based on the simulation results obtained, the highest strength of the electric field distribution was generated by the ring electrode pattern 5.22  106 V/m produced and the DEP force was 1.42  10-13N. The ripple pattern electrode generated 2.04  107 V/m of electric field and the DEP force produced was 4.19  10-11 N which was higher than the ring electrode. It was found that the temperature rise issues can be controlled based on simulation results by reducing the voltage by half, yet electric field can generate higher electric field strength. The percentage increase in electric field strength of ring microelectrode and ripple microelectrode was 86.86% and 47.55%, respectively. The results showed that the distance between the microelectrodes and micro-cavity provided more impact in electrical field distribution strength compared to the change of the microelectrodes dimension. The resulting electrical field strength was high between the microelectrodes tip and edge of the micro-cavities. Cell trapping may also occur in the central part of the micro-cavities with nDEP where the cells were attracted to the areas of low electric field. On the other hand, when pDEP was used, cells were attracted to the edge of micro-cavities where the high electric field region occurred. With the simulation and analysis obtained, designed microelectrode was able to trap the cells. This research work became an attempt to find a biochip design, in order to get the better electrode design patterns which offered higher efficiency in manipulating and trapping the biological cells." @default.
• W2912497171 created "2019-02-21" @default.
• W2912497171 creator A5029520984 @default.
• W2912497171 creator A5067758299 @default.
• W2912497171 date "2018-01-01" @default.
• W2912497171 modified "2023-09-24" @default.
• W2912497171 title "Enhancement of ring and ripple microelectrodes design using dielectrophoresis (DEP) for biochip application" @default.
• W2912497171 hasPublicationYear "2018" @default.
• W2912497171 type Work @default.
• W2912497171 sameAs 2912497171 @default.
• W2912497171 citedByCount "0" @default.
• W2912497171 crossrefType "dissertation" @default.
• W2912497171 hasAuthorship W2912497171A5029520984 @default.
• W2912497171 hasAuthorship W2912497171A5067758299 @default.
• W2912497171 hasConcept C106825181 @default.
• W2912497171 hasConcept C111670793 @default.
• W2912497171 hasConcept C119599485 @default.
• W2912497171 hasConcept C121332964 @default.
• W2912497171 hasConcept C127413603 @default.
• W2912497171 hasConcept C135628077 @default.
• W2912497171 hasConcept C147789679 @default.
• W2912497171 hasConcept C165801399 @default.
• W2912497171 hasConcept C171250308 @default.
• W2912497171 hasConcept C17525397 @default.
• W2912497171 hasConcept C185592680 @default.
• W2912497171 hasConcept C192562407 @default.
• W2912497171 hasConcept C2779599953 @default.
• W2912497171 hasConcept C41008148 @default.
• W2912497171 hasConcept C46435376 @default.
• W2912497171 hasConcept C60799052 @default.
• W2912497171 hasConcept C62520636 @default.
• W2912497171 hasConcept C66938386 @default.
• W2912497171 hasConcept C8673954 @default.
• W2912497171 hasConcept C87892846 @default.
• W2912497171 hasConcept C95967509 @default.
• W2912497171 hasConcept C97562148 @default.
• W2912497171 hasConceptScore W2912497171C106825181 @default.
• W2912497171 hasConceptScore W2912497171C111670793 @default.
• W2912497171 hasConceptScore W2912497171C119599485 @default.
• W2912497171 hasConceptScore W2912497171C121332964 @default.
• W2912497171 hasConceptScore W2912497171C127413603 @default.
• W2912497171 hasConceptScore W2912497171C135628077 @default.
• W2912497171 hasConceptScore W2912497171C147789679 @default.
• W2912497171 hasConceptScore W2912497171C165801399 @default.
• W2912497171 hasConceptScore W2912497171C171250308 @default.
• W2912497171 hasConceptScore W2912497171C17525397 @default.
• W2912497171 hasConceptScore W2912497171C185592680 @default.
• W2912497171 hasConceptScore W2912497171C192562407 @default.
• W2912497171 hasConceptScore W2912497171C2779599953 @default.
• W2912497171 hasConceptScore W2912497171C41008148 @default.
• W2912497171 hasConceptScore W2912497171C46435376 @default.
• W2912497171 hasConceptScore W2912497171C60799052 @default.
• W2912497171 hasConceptScore W2912497171C62520636 @default.
• W2912497171 hasConceptScore W2912497171C66938386 @default.
• W2912497171 hasConceptScore W2912497171C8673954 @default.
• W2912497171 hasConceptScore W2912497171C87892846 @default.
• W2912497171 hasConceptScore W2912497171C95967509 @default.
• W2912497171 hasConceptScore W2912497171C97562148 @default.
• W2912497171 hasLocation W29124971711 @default.
• W2912497171 hasOpenAccess W2912497171 @default.
• W2912497171 hasPrimaryLocation W29124971711 @default.
• W2912497171 hasRelatedWork W1962297411 @default.
• W2912497171 hasRelatedWork W1981883576 @default.
• W2912497171 hasRelatedWork W2050946270 @default.
• W2912497171 hasRelatedWork W2054866946 @default.
• W2912497171 hasRelatedWork W2061381544 @default.
• W2912497171 hasRelatedWork W2068474023 @default.
• W2912497171 hasRelatedWork W2075612857 @default.
• W2912497171 hasRelatedWork W2078165170 @default.
• W2912497171 hasRelatedWork W2087531284 @default.
• W2912497171 hasRelatedWork W2247835399 @default.
• W2912497171 hasRelatedWork W2266670821 @default.
• W2912497171 hasRelatedWork W2297805808 @default.
• W2912497171 hasRelatedWork W2316292480 @default.
• W2912497171 hasRelatedWork W2401984052 @default.
• W2912497171 hasRelatedWork W2481377080 @default.
• W2912497171 hasRelatedWork W2524153561 @default.
• W2912497171 hasRelatedWork W2606390212 @default.
• W2912497171 hasRelatedWork W2795339906 @default.
• W2912497171 hasRelatedWork W2903847017 @default.
• W2912497171 hasRelatedWork W1968829233 @default.
• W2912497171 isParatext "false" @default.
• W2912497171 isRetracted "false" @default.
• W2912497171 magId "2912497171" @default.
• W2912497171 workType "dissertation" @default.