FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912500328> ?p ?o ?g. }

• W2912500328 endingPage "10" @default.
• W2912500328 startingPage "1" @default.
• W2912500328 abstract "Amaranthus retroflexus L., an introduced invasive weed in southern Australia, has been associated with acute renal failure and/or mortality in a number of livestock species. While its leaves, flowers and stems are generally reported to contain high levels of nitrogen, few studies have fully characterised the chemical composition of A. retroflexus foliage with respect to mammalian toxicity. We performed extensive metabolic profiling of stems, leaves, roots and inflorescence tissues of A. retroflexus collected from three spatially and/or temporally distinct toxicity outbreaks, and report on the 1) composition of primary and secondary metabolites in methanolic extracts of A. retroflexus tissues using HPLC and HPLC-MS QToF and 2) chemometric analysis of A. retroflexus extracts in relation to the associated toxin(s). All tissues of A. retroflexus possessed an abundance of N-containing metabolites, particularly quaternary ammonium compounds which were identified as betaines, two of which (valine betaine and isoleucine betaine) are rarely encountered in plants. Cytotoxicity to murine fibroblasts was highest in extracts of leaf tissue and was associated with a single, a small modified peptide with high similarity to N-acetyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-O-(carboxymethyl)-L-tyrosyl-L-leucinamide, a synthetic phosphotyrosyl mimic involved in cell signaling processes. One possible mode of action leading to acute renal failure in grazing livestock by a modified peptide such as this is proposed." @default.
• W2912500328 created "2019-02-21" @default.
• W2912500328 creator A5000493990 @default.
• W2912500328 creator A5002248034 @default.
• W2912500328 creator A5014104177 @default.
• W2912500328 creator A5046318072 @default.
• W2912500328 creator A5065189365 @default.
• W2912500328 creator A5077945849 @default.
• W2912500328 date "2019-05-01" @default.
• W2912500328 modified "2023-10-18" @default.
• W2912500328 title "Chemometric analysis of Amaranthus retroflexus in relation to livestock toxicity in southern Australia" @default.
• W2912500328 cites W1526960265 @default.
• W2912500328 cites W1904126509 @default.
• W2912500328 cites W1931636434 @default.
• W2912500328 cites W1942126542 @default.
• W2912500328 cites W1966735054 @default.
• W2912500328 cites W1966995314 @default.
• W2912500328 cites W1967347166 @default.
• W2912500328 cites W1970079409 @default.
• W2912500328 cites W1981971275 @default.
• W2912500328 cites W1991127562 @default.
• W2912500328 cites W1993247518 @default.
• W2912500328 cites W1999010761 @default.
• W2912500328 cites W2005399097 @default.
• W2912500328 cites W2007086411 @default.
• W2912500328 cites W2020695467 @default.
• W2912500328 cites W2026866182 @default.
• W2912500328 cites W2030107346 @default.
• W2912500328 cites W2030385971 @default.
• W2912500328 cites W2050109742 @default.
• W2912500328 cites W2054398949 @default.
• W2912500328 cites W2058157372 @default.
• W2912500328 cites W2074388946 @default.
• W2912500328 cites W2074720507 @default.
• W2912500328 cites W2074887740 @default.
• W2912500328 cites W2075984087 @default.
• W2912500328 cites W2082497295 @default.
• W2912500328 cites W2087197447 @default.
• W2912500328 cites W2093018080 @default.
• W2912500328 cites W2121879231 @default.
• W2912500328 cites W2126366476 @default.
• W2912500328 cites W2136027907 @default.
• W2912500328 cites W2145651065 @default.
• W2912500328 cites W2148874125 @default.
• W2912500328 cites W2154575988 @default.
• W2912500328 cites W2154946744 @default.
• W2912500328 cites W2156632286 @default.
• W2912500328 cites W2159766106 @default.
• W2912500328 cites W2167078135 @default.
• W2912500328 cites W2169584935 @default.
• W2912500328 cites W2293687544 @default.
• W2912500328 cites W2345614947 @default.
• W2912500328 cites W2534308464 @default.
• W2912500328 cites W2589947943 @default.
• W2912500328 cites W2590130944 @default.
• W2912500328 cites W2682016901 @default.
• W2912500328 cites W2951494886 @default.
• W2912500328 cites W4231976120 @default.
• W2912500328 doi "https://doi.org/10.1016/j.phytochem.2019.01.016" @default.
• W2912500328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30776591" @default.
• W2912500328 hasPublicationYear "2019" @default.
• W2912500328 type Work @default.
• W2912500328 sameAs 2912500328 @default.
• W2912500328 citedByCount "8" @default.
• W2912500328 countsByYear W29125003282019 @default.
• W2912500328 countsByYear W29125003282021 @default.
• W2912500328 countsByYear W29125003282023 @default.
• W2912500328 crossrefType "journal-article" @default.
• W2912500328 hasAuthorship W2912500328A5000493990 @default.
• W2912500328 hasAuthorship W2912500328A5002248034 @default.
• W2912500328 hasAuthorship W2912500328A5014104177 @default.
• W2912500328 hasAuthorship W2912500328A5046318072 @default.
• W2912500328 hasAuthorship W2912500328A5065189365 @default.
• W2912500328 hasAuthorship W2912500328A5077945849 @default.
• W2912500328 hasConcept C116263406 @default.
• W2912500328 hasConcept C178790620 @default.
• W2912500328 hasConcept C185592680 @default.
• W2912500328 hasConcept C2775891814 @default.
• W2912500328 hasConcept C2777248517 @default.
• W2912500328 hasConcept C2777573094 @default.
• W2912500328 hasConcept C29730261 @default.
• W2912500328 hasConcept C515207424 @default.
• W2912500328 hasConcept C55493867 @default.
• W2912500328 hasConcept C59822182 @default.
• W2912500328 hasConcept C86803240 @default.
• W2912500328 hasConceptScore W2912500328C116263406 @default.
• W2912500328 hasConceptScore W2912500328C178790620 @default.
• W2912500328 hasConceptScore W2912500328C185592680 @default.
• W2912500328 hasConceptScore W2912500328C2775891814 @default.
• W2912500328 hasConceptScore W2912500328C2777248517 @default.
• W2912500328 hasConceptScore W2912500328C2777573094 @default.
• W2912500328 hasConceptScore W2912500328C29730261 @default.
• W2912500328 hasConceptScore W2912500328C515207424 @default.
• W2912500328 hasConceptScore W2912500328C55493867 @default.
• W2912500328 hasConceptScore W2912500328C59822182 @default.
• W2912500328 hasConceptScore W2912500328C86803240 @default.
• W2912500328 hasLocation W29125003281 @default.
• W2912500328 hasLocation W29125003282 @default.

• next