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- W2912502670 abstract "We appreciate the comments made by Lee et al and Roach et al related to our report comparing external beam radiotherapy (EBRT) and brachytherapy (BRT) in the treatment of favorable- and intermediate-risk prostate cancer. We, of course, acknowledged in the paper that this study is not a Phase III randomized trial, and thus definitive conclusions regarding the superiority of one treatment cannot be made. We also acknowledged within the paper that, given the retrospective nature of our study, inherent selection biases and other possible confounders are likely present that limit our ability to draw conclusions concerning the strength of one treatment over another. To address this concern, a Cox regression analysis was performed; yet we concur that other variables not included in the regression model or unknown issues may have possibly played a role in explaining the superiority of BRT in our study. Editorial CommentUrologyVol. 77Issue 4PreviewIn this issue of Urology, Zelefsky et al. retrospectively compared men with low-risk prostate cancer treated with either intensity-modulated radiotherapy (IMRT) or a permanent prostate seed implant (PPI).1 The authors conclude that the 7-year control was better for PPI than IMRT. Investigators from the University of California–San Francisco and from Vancouver have recently reported similar conclusions concerning outcomes in patients after PPI compared with patients treated with conventional external beam radiation therapy (EBRT), three-dimensional conformal (3D-CRT), or IMRT techniques. Full-Text PDF" @default.
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- W2912502670 date "2011-04-01" @default.
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- W2912502670 title "Reply" @default.
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- W2912502670 doi "https://doi.org/10.1016/j.urology.2010.09.037" @default.
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