Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912503883> ?p ?o ?g. }
- W2912503883 endingPage "59" @default.
- W2912503883 startingPage "41" @default.
- W2912503883 abstract "Recovery of patients with rheumatoid arthritis (RA) depends on several physical and psychological factors, besides pharmacological treatment. Co-morbid depression adversely affects the outcome in RA. Usual medical therapies have a limited scope and fail to cure the psychological component of the disease. With advanced therapeutic options, achieving a state of remission has become the treatment goal, yoga based mind body intervention (MBI) may provide a holistic approach in its treatment dimension. Hence, MBIs are the need of hour as majority of diseases have a psychosomatic component.To explore the effect of Yoga based MBI on disease specific inflammatory markers and depression severity in active RA patients on routine disease modifying anti-rheumatic drugs (DMARDs) therapy.A total of 72 RA patients were randomized into 2 groups: yoga group (yoga with DMARDs) and control group (DMARDs only). Blood samples were collected pre and post intervention for primary outcome measurements of systemic biomarkers. Disease activity score 28, erythrocyte sedimentation rate (DAS28ESR) and health assessment questionnaire disability index (HAQ-DI) were used to assess disease activity and functional status respectively at pre and post intervention time-points. Secondary outcome, depression severity, was assessed by Beck Depression Inventory II scale (BDI-II) at 2 weekly intervals during 8 weeks of the study interventional plan.After 8 weeks of yoga based MBI, there was significant decrease in the severity of RA as seen by reduction in levels of various systemic inflammatory markers as well as in DAS28ESR (p-value <0.0001; effect size = 0.210) and HAQ-DI (p-value 0.001; effect size = 0.159). Also, yoga group experienced a statistically significant time dependent step-wise decline in depression symptoms over the period of 8 weeks as compared to control group (p-value <0.0001; effect size = 0.5). Regression analysis showed greater reduction in the scores of BDI-II with DAS28ESR (R2 = 0.426; p < 0.0001) and HAQ-DI (R2 = 0.236; p = 0.003) in yoga group.Yoga, a mind body intervention re-established immunological tolerance by aiding remission at molecular and cellular level along with significant reduction in depression. Thus in this severe autoimmune inflammatory arthritis with a major psychosomatic component, yoga can be used as a complementary/adjunct therapy." @default.
- W2912503883 created "2019-02-21" @default.
- W2912503883 creator A5030297371 @default.
- W2912503883 creator A5035432233 @default.
- W2912503883 creator A5038201033 @default.
- W2912503883 creator A5058351630 @default.
- W2912503883 date "2019-03-06" @default.
- W2912503883 modified "2023-10-14" @default.
- W2912503883 title "Impact of yoga based mind-body intervention on systemic inflammatory markers and co-morbid depression in active Rheumatoid arthritis patients: A randomized controlled trial" @default.
- W2912503883 cites W1035574158 @default.
- W2912503883 cites W1552644771 @default.
- W2912503883 cites W1968311523 @default.
- W2912503883 cites W1973049703 @default.
- W2912503883 cites W1980326460 @default.
- W2912503883 cites W1988842291 @default.
- W2912503883 cites W1992731182 @default.
- W2912503883 cites W1997785527 @default.
- W2912503883 cites W2001069355 @default.
- W2912503883 cites W2018416312 @default.
- W2912503883 cites W2019946809 @default.
- W2912503883 cites W2020858697 @default.
- W2912503883 cites W2021845813 @default.
- W2912503883 cites W2025810782 @default.
- W2912503883 cites W2026025331 @default.
- W2912503883 cites W2026434512 @default.
- W2912503883 cites W2037557484 @default.
- W2912503883 cites W2038593306 @default.
- W2912503883 cites W2039266834 @default.
- W2912503883 cites W2041765228 @default.
- W2912503883 cites W2049594274 @default.
- W2912503883 cites W2050712261 @default.
- W2912503883 cites W2061931936 @default.
- W2912503883 cites W2062149404 @default.
- W2912503883 cites W2067557887 @default.
- W2912503883 cites W2088684133 @default.
- W2912503883 cites W2090656404 @default.
- W2912503883 cites W2091973725 @default.
- W2912503883 cites W2094482876 @default.
- W2912503883 cites W2102709362 @default.
- W2912503883 cites W2103837216 @default.
- W2912503883 cites W2110826367 @default.
- W2912503883 cites W2114495840 @default.
- W2912503883 cites W2115654515 @default.
- W2912503883 cites W2121755167 @default.
- W2912503883 cites W2123277906 @default.
- W2912503883 cites W2124516437 @default.
- W2912503883 cites W2126737053 @default.
- W2912503883 cites W2134903824 @default.
- W2912503883 cites W2143632050 @default.
- W2912503883 cites W2145220156 @default.
- W2912503883 cites W2151628746 @default.
- W2912503883 cites W2152141502 @default.
- W2912503883 cites W2153738351 @default.
- W2912503883 cites W2160621707 @default.
- W2912503883 cites W2163249197 @default.
- W2912503883 cites W2279648693 @default.
- W2912503883 cites W2287283884 @default.
- W2912503883 cites W2342776269 @default.
- W2912503883 cites W2363535642 @default.
- W2912503883 cites W2414591521 @default.
- W2912503883 cites W2471463846 @default.
- W2912503883 cites W2471730875 @default.
- W2912503883 cites W2474137413 @default.
- W2912503883 cites W2562443541 @default.
- W2912503883 cites W2579512273 @default.
- W2912503883 cites W2596424078 @default.
- W2912503883 cites W2602053821 @default.
- W2912503883 cites W2605105015 @default.
- W2912503883 cites W2614159278 @default.
- W2912503883 cites W2753480688 @default.
- W2912503883 cites W2759264167 @default.
- W2912503883 cites W2789565293 @default.
- W2912503883 cites W2794914738 @default.
- W2912503883 cites W2884079583 @default.
- W2912503883 cites W2899494011 @default.
- W2912503883 cites W2916776794 @default.
- W2912503883 cites W4238801120 @default.
- W2912503883 cites W4249632605 @default.
- W2912503883 doi "https://doi.org/10.3233/rnn-180875" @default.
- W2912503883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30714983" @default.
- W2912503883 hasPublicationYear "2019" @default.
- W2912503883 type Work @default.
- W2912503883 sameAs 2912503883 @default.
- W2912503883 citedByCount "37" @default.
- W2912503883 countsByYear W29125038832019 @default.
- W2912503883 countsByYear W29125038832020 @default.
- W2912503883 countsByYear W29125038832021 @default.
- W2912503883 countsByYear W29125038832022 @default.
- W2912503883 countsByYear W29125038832023 @default.
- W2912503883 crossrefType "journal-article" @default.
- W2912503883 hasAuthorship W2912503883A5030297371 @default.
- W2912503883 hasAuthorship W2912503883A5035432233 @default.
- W2912503883 hasAuthorship W2912503883A5038201033 @default.
- W2912503883 hasAuthorship W2912503883A5058351630 @default.
- W2912503883 hasConcept C118552586 @default.
- W2912503883 hasConcept C126322002 @default.
- W2912503883 hasConcept C139719470 @default.
- W2912503883 hasConcept C159110408 @default.