Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912522072> ?p ?o ?g. }
- W2912522072 abstract "Nanotechnology is an expanding interdisciplinary field concerning the development and application of nanostructured materials derived from inorganic compounds or organic polymers and peptides. Among these latter materials, proteinaceous plant virus nanoparticles have emerged as a key platform for the introduction of tailored functionalities by genetic engineering and conjugation chemistry. Tobacco mosaic virus and Cowpea mosaic virus have already been developed for bioimaging, vaccination and electronics applications, but the flexible and filamentous Potato virus X (PVX) has received comparatively little attention. The filamentous structure of PVX particles allows them to carry large payloads, which are advantageous for applications such as biomedical imaging in which multi-functional scaffolds with a high aspect ratio are required. In this context, PVX achieves superior tumor homing and retention properties compared to spherical nanoparticles. Because PVX is a protein-based nanoparticle, its unique functional properties are combined with enhanced biocompatibility, making it much more suitable for biomedical applications than synthetic nanomaterials. Moreover, PVX nanoparticles have very low toxicity in vivo, and superior pharmacokinetic profiles. This review focuses on the production of PVX nanoparticles engineered using chemical and/or biological techniques, and describes current and future opportunities and challenges for the application of PVX nanoparticles in medicine, diagnostics, materials science and biocatalysis." @default.
- W2912522072 created "2019-02-21" @default.
- W2912522072 creator A5019412759 @default.
- W2912522072 creator A5036549419 @default.
- W2912522072 creator A5050798048 @default.
- W2912522072 date "2019-02-19" @default.
- W2912522072 modified "2023-10-16" @default.
- W2912522072 title "Small, Smaller, Nano: New Applications for Potato Virus X in Nanotechnology" @default.
- W2912522072 cites W1491058174 @default.
- W2912522072 cites W1543075094 @default.
- W2912522072 cites W1557503174 @default.
- W2912522072 cites W1557701570 @default.
- W2912522072 cites W1566467827 @default.
- W2912522072 cites W1571197643 @default.
- W2912522072 cites W1571910039 @default.
- W2912522072 cites W1727412066 @default.
- W2912522072 cites W1799111770 @default.
- W2912522072 cites W1827539236 @default.
- W2912522072 cites W1861441728 @default.
- W2912522072 cites W1904003583 @default.
- W2912522072 cites W1946677432 @default.
- W2912522072 cites W1963866489 @default.
- W2912522072 cites W1964135400 @default.
- W2912522072 cites W1964146854 @default.
- W2912522072 cites W1964755011 @default.
- W2912522072 cites W1965097716 @default.
- W2912522072 cites W1965625212 @default.
- W2912522072 cites W1970502264 @default.
- W2912522072 cites W1971042251 @default.
- W2912522072 cites W1973412354 @default.
- W2912522072 cites W1975738088 @default.
- W2912522072 cites W1976672416 @default.
- W2912522072 cites W1977114412 @default.
- W2912522072 cites W1977400619 @default.
- W2912522072 cites W1977457835 @default.
- W2912522072 cites W1977634109 @default.
- W2912522072 cites W1978678743 @default.
- W2912522072 cites W1981387297 @default.
- W2912522072 cites W1984805716 @default.
- W2912522072 cites W1985037778 @default.
- W2912522072 cites W1989588009 @default.
- W2912522072 cites W1989945146 @default.
- W2912522072 cites W1990094445 @default.
- W2912522072 cites W1994325381 @default.
- W2912522072 cites W1995237117 @default.
- W2912522072 cites W1996192845 @default.
- W2912522072 cites W1996540389 @default.
- W2912522072 cites W1997236997 @default.
- W2912522072 cites W1999281495 @default.
- W2912522072 cites W1999762279 @default.
- W2912522072 cites W2000194719 @default.
- W2912522072 cites W2001981376 @default.
- W2912522072 cites W2002306218 @default.
- W2912522072 cites W2002369017 @default.
- W2912522072 cites W2002592834 @default.
- W2912522072 cites W2003697352 @default.
- W2912522072 cites W2003707680 @default.
- W2912522072 cites W2004118070 @default.
- W2912522072 cites W2005653734 @default.
- W2912522072 cites W2006459863 @default.
- W2912522072 cites W2008226030 @default.
- W2912522072 cites W2010265091 @default.
- W2912522072 cites W2013211632 @default.
- W2912522072 cites W2013479636 @default.
- W2912522072 cites W2013722923 @default.
- W2912522072 cites W2020065174 @default.
- W2912522072 cites W2021322124 @default.
- W2912522072 cites W2022277849 @default.
- W2912522072 cites W2022488471 @default.
- W2912522072 cites W2025279111 @default.
- W2912522072 cites W2027017689 @default.
- W2912522072 cites W2027600991 @default.
- W2912522072 cites W2030784298 @default.
- W2912522072 cites W2031094501 @default.
- W2912522072 cites W2031725338 @default.
- W2912522072 cites W2034911101 @default.
- W2912522072 cites W2035029057 @default.
- W2912522072 cites W2036109942 @default.
- W2912522072 cites W2036961324 @default.
- W2912522072 cites W2037248548 @default.
- W2912522072 cites W2038894713 @default.
- W2912522072 cites W2039739851 @default.
- W2912522072 cites W2039980395 @default.
- W2912522072 cites W2040278281 @default.
- W2912522072 cites W2040449739 @default.
- W2912522072 cites W2043633676 @default.
- W2912522072 cites W2046182783 @default.
- W2912522072 cites W2048299290 @default.
- W2912522072 cites W2049588389 @default.
- W2912522072 cites W2049663107 @default.
- W2912522072 cites W2050622829 @default.
- W2912522072 cites W2050947321 @default.
- W2912522072 cites W2052274396 @default.
- W2912522072 cites W2053795281 @default.
- W2912522072 cites W2055715280 @default.
- W2912522072 cites W2059422902 @default.
- W2912522072 cites W2062063474 @default.
- W2912522072 cites W2062230922 @default.
- W2912522072 cites W2064255874 @default.
- W2912522072 cites W2066744217 @default.