FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912571180> ?p ?o ?g. }

• W2912571180 endingPage "39" @default.
• W2912571180 startingPage "35" @default.
• W2912571180 abstract "An amino-thiazolidinone platinum(II) compound which could rapidly induce apoptosis in tumor cells and showed no cross resistance against the cisplatin-resistant cells, was firstly to study of protein-drug interactions. To investigate the potential of Pt(II) compounds as therapeutic drugs, two Pt(II) complexes (1 and 2) were explored the influences based on their interaction in vitro with human serum albumin (HSA) by fluorescence spectrometry and UV–Vis absorption. The binding interactions of two compounds with HSA results in the formation of corresponding HSA-drug complexes, van der Waals forces and hydrogen bonding played key roles in stabilizing these complexes. Both of two compounds were through a dynamic quenching mechanism, this dynamic reversible binding process was of great significance to the equilibrium of drug concentrations in vivo, which ensured that the internal environment of the organism was in a relatively stable state." @default.
• W2912571180 created "2019-02-21" @default.
• W2912571180 creator A5039568378 @default.
• W2912571180 creator A5044544424 @default.
• W2912571180 creator A5056760789 @default.
• W2912571180 creator A5074926427 @default.
• W2912571180 date "2019-04-01" @default.
• W2912571180 modified "2023-10-15" @default.
• W2912571180 title "Spectroscopic investigations of the interactions of potential antitumor amino-thiazolidinone platinum (II) compounds with human serum albumin" @default.
• W2912571180 cites W1462570225 @default.
• W2912571180 cites W1985246859 @default.
• W2912571180 cites W2010895582 @default.
• W2912571180 cites W2014950975 @default.
• W2912571180 cites W2029639743 @default.
• W2912571180 cites W2035884057 @default.
• W2912571180 cites W2041777349 @default.
• W2912571180 cites W2052204371 @default.
• W2912571180 cites W2092555653 @default.
• W2912571180 cites W2103329971 @default.
• W2912571180 cites W2203908584 @default.
• W2912571180 cites W2313816934 @default.
• W2912571180 cites W2325878452 @default.
• W2912571180 cites W2344445259 @default.
• W2912571180 cites W2591905283 @default.
• W2912571180 cites W2602912558 @default.
• W2912571180 cites W2782350396 @default.
• W2912571180 cites W2886465223 @default.
• W2912571180 doi "https://doi.org/10.1016/j.inoche.2019.02.001" @default.
• W2912571180 hasPublicationYear "2019" @default.
• W2912571180 type Work @default.
• W2912571180 sameAs 2912571180 @default.
• W2912571180 citedByCount "3" @default.
• W2912571180 countsByYear W29125711802019 @default.
• W2912571180 countsByYear W29125711802020 @default.
• W2912571180 countsByYear W29125711802021 @default.
• W2912571180 crossrefType "journal-article" @default.
• W2912571180 hasAuthorship W2912571180A5039568378 @default.
• W2912571180 hasAuthorship W2912571180A5044544424 @default.
• W2912571180 hasAuthorship W2912571180A5056760789 @default.
• W2912571180 hasAuthorship W2912571180A5074926427 @default.
• W2912571180 hasConcept C112887158 @default.
• W2912571180 hasConcept C121332964 @default.
• W2912571180 hasConcept C121745418 @default.
• W2912571180 hasConcept C126061179 @default.
• W2912571180 hasConcept C150903083 @default.
• W2912571180 hasConcept C161790260 @default.
• W2912571180 hasConcept C165616093 @default.
• W2912571180 hasConcept C178790620 @default.
• W2912571180 hasConcept C185592680 @default.
• W2912571180 hasConcept C202751555 @default.
• W2912571180 hasConcept C207001950 @default.
• W2912571180 hasConcept C21951064 @default.
• W2912571180 hasConcept C2776125364 @default.
• W2912571180 hasConcept C2776694085 @default.
• W2912571180 hasConcept C2778239845 @default.
• W2912571180 hasConcept C2778597219 @default.
• W2912571180 hasConcept C2780035454 @default.
• W2912571180 hasConcept C32909587 @default.
• W2912571180 hasConcept C518104683 @default.
• W2912571180 hasConcept C54355233 @default.
• W2912571180 hasConcept C55493867 @default.
• W2912571180 hasConcept C62520636 @default.
• W2912571180 hasConcept C71240020 @default.
• W2912571180 hasConcept C86803240 @default.
• W2912571180 hasConcept C86807702 @default.
• W2912571180 hasConcept C90260826 @default.
• W2912571180 hasConcept C91881484 @default.
• W2912571180 hasConcept C98274493 @default.
• W2912571180 hasConceptScore W2912571180C112887158 @default.
• W2912571180 hasConceptScore W2912571180C121332964 @default.
• W2912571180 hasConceptScore W2912571180C121745418 @default.
• W2912571180 hasConceptScore W2912571180C126061179 @default.
• W2912571180 hasConceptScore W2912571180C150903083 @default.
• W2912571180 hasConceptScore W2912571180C161790260 @default.
• W2912571180 hasConceptScore W2912571180C165616093 @default.
• W2912571180 hasConceptScore W2912571180C178790620 @default.
• W2912571180 hasConceptScore W2912571180C185592680 @default.
• W2912571180 hasConceptScore W2912571180C202751555 @default.
• W2912571180 hasConceptScore W2912571180C207001950 @default.
• W2912571180 hasConceptScore W2912571180C21951064 @default.
• W2912571180 hasConceptScore W2912571180C2776125364 @default.
• W2912571180 hasConceptScore W2912571180C2776694085 @default.
• W2912571180 hasConceptScore W2912571180C2778239845 @default.
• W2912571180 hasConceptScore W2912571180C2778597219 @default.
• W2912571180 hasConceptScore W2912571180C2780035454 @default.
• W2912571180 hasConceptScore W2912571180C32909587 @default.
• W2912571180 hasConceptScore W2912571180C518104683 @default.
• W2912571180 hasConceptScore W2912571180C54355233 @default.
• W2912571180 hasConceptScore W2912571180C55493867 @default.
• W2912571180 hasConceptScore W2912571180C62520636 @default.
• W2912571180 hasConceptScore W2912571180C71240020 @default.
• W2912571180 hasConceptScore W2912571180C86803240 @default.
• W2912571180 hasConceptScore W2912571180C86807702 @default.
• W2912571180 hasConceptScore W2912571180C90260826 @default.
• W2912571180 hasConceptScore W2912571180C91881484 @default.
• W2912571180 hasConceptScore W2912571180C98274493 @default.
• W2912571180 hasFunder F4320321001 @default.
• W2912571180 hasLocation W29125711801 @default.

• next