FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912579623> ?p ?o ?g. }

• W2912579623 endingPage "65" @default.
• W2912579623 startingPage "59" @default.
• W2912579623 abstract "The role of neoadjuvant chemotherapy (NAC) for the management of upper tract urothelial carcinoma (UTUC) remains controversial. The aim of present study was to evaluate the contemporary role of NAC for patients with locally advanced UTUC through systematic review and meta-analysis of the literature. Systematic literature searches were conducted in PubMed/Medline and Embase for all studies that examined the role of chemotherapy for UTUC. We performed this study according to the Preferred Reported Items for Systematic Reviews and Meta-analysis guidelines. Endpoints were overall survival (OS), cancer-specific survival (CSS), and progression-free survival (PFS). A total of four trials on 318 patients were included in this study. Each of the included studies was retrospective. Compared to controls, NAC improved OS, CSS, and PFS by 57% (95% confidence interval [CI], 0.25–0.73; p = 0.002), 59% (95% CI, 0.27–0.57; p < 0.00001), and 45% (95% CI, 0.50–0.60; p < 0.00001), respectively. The absolute increases in OS, CSS, and PFS were 11%, 18%, and 13%, respectively, and these increases are equivalent to numbers-needed-to-treat of 9, 5.5, and 7.6, respectively. Pooled odds ratio for the effect of NAC on downstaging was 0.21 (95% CI, 0.09–0.60; p = 0.004), which indicates that NAC group had a 4.76-fold higher probability of having pathologic N stage 0 than control group. NAC treatment before radical nephroureterectomy might provide better survival outcomes in patients with locally advanced UTUC. Prospective randomized studies are needed to confirm the benefits of NAC in locally advanced UTUC patients." @default.
• W2912579623 created "2019-02-21" @default.
• W2912579623 creator A5024153128 @default.
• W2912579623 creator A5045730291 @default.
• W2912579623 creator A5048382900 @default.
• W2912579623 creator A5078416571 @default.
• W2912579623 creator A5083434927 @default.
• W2912579623 date "2019-03-01" @default.
• W2912579623 modified "2023-09-27" @default.
• W2912579623 title "Effect of neoadjuvant chemotherapy on locally advanced upper tract urothelial carcinoma: A systematic review and meta-analysis" @default.
• W2912579623 cites W1484305797 @default.
• W2912579623 cites W1527366898 @default.
• W2912579623 cites W1942258069 @default.
• W2912579623 cites W1967046314 @default.
• W2912579623 cites W1974484906 @default.
• W2912579623 cites W1980525903 @default.
• W2912579623 cites W1987637912 @default.
• W2912579623 cites W2008374274 @default.
• W2912579623 cites W2014370222 @default.
• W2912579623 cites W2032471331 @default.
• W2912579623 cites W2071772756 @default.
• W2912579623 cites W2073821754 @default.
• W2912579623 cites W2075642745 @default.
• W2912579623 cites W2083397917 @default.
• W2912579623 cites W2117289541 @default.
• W2912579623 cites W2118581974 @default.
• W2912579623 cites W2124215423 @default.
• W2912579623 cites W2125435699 @default.
• W2912579623 cites W2134236426 @default.
• W2912579623 cites W2138439591 @default.
• W2912579623 cites W2165010366 @default.
• W2912579623 cites W2166453367 @default.
• W2912579623 cites W2171883057 @default.
• W2912579623 cites W2262926055 @default.
• W2912579623 cites W2522804697 @default.
• W2912579623 cites W2582834090 @default.
• W2912579623 cites W2604655222 @default.
• W2912579623 cites W2738200477 @default.
• W2912579623 cites W2763573858 @default.
• W2912579623 cites W2788536359 @default.
• W2912579623 cites W2804629518 @default.
• W2912579623 doi "https://doi.org/10.1016/j.critrevonc.2019.01.019" @default.
• W2912579623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30819447" @default.
• W2912579623 hasPublicationYear "2019" @default.
• W2912579623 type Work @default.
• W2912579623 sameAs 2912579623 @default.
• W2912579623 citedByCount "33" @default.
• W2912579623 countsByYear W29125796232019 @default.
• W2912579623 countsByYear W29125796232020 @default.
• W2912579623 countsByYear W29125796232021 @default.
• W2912579623 countsByYear W29125796232022 @default.
• W2912579623 countsByYear W29125796232023 @default.
• W2912579623 crossrefType "journal-article" @default.
• W2912579623 hasAuthorship W2912579623A5024153128 @default.
• W2912579623 hasAuthorship W2912579623A5045730291 @default.
• W2912579623 hasAuthorship W2912579623A5048382900 @default.
• W2912579623 hasAuthorship W2912579623A5078416571 @default.
• W2912579623 hasAuthorship W2912579623A5083434927 @default.
• W2912579623 hasConcept C126322002 @default.
• W2912579623 hasConcept C126894567 @default.
• W2912579623 hasConcept C143998085 @default.
• W2912579623 hasConcept C146357865 @default.
• W2912579623 hasConcept C151730666 @default.
• W2912579623 hasConcept C156957248 @default.
• W2912579623 hasConcept C168563851 @default.
• W2912579623 hasConcept C17744445 @default.
• W2912579623 hasConcept C199539241 @default.
• W2912579623 hasConcept C2776694085 @default.
• W2912579623 hasConcept C2779473830 @default.
• W2912579623 hasConcept C44249647 @default.
• W2912579623 hasConcept C71924100 @default.
• W2912579623 hasConcept C86803240 @default.
• W2912579623 hasConcept C95190672 @default.
• W2912579623 hasConceptScore W2912579623C126322002 @default.
• W2912579623 hasConceptScore W2912579623C126894567 @default.
• W2912579623 hasConceptScore W2912579623C143998085 @default.
• W2912579623 hasConceptScore W2912579623C146357865 @default.
• W2912579623 hasConceptScore W2912579623C151730666 @default.
• W2912579623 hasConceptScore W2912579623C156957248 @default.
• W2912579623 hasConceptScore W2912579623C168563851 @default.
• W2912579623 hasConceptScore W2912579623C17744445 @default.
• W2912579623 hasConceptScore W2912579623C199539241 @default.
• W2912579623 hasConceptScore W2912579623C2776694085 @default.
• W2912579623 hasConceptScore W2912579623C2779473830 @default.
• W2912579623 hasConceptScore W2912579623C44249647 @default.
• W2912579623 hasConceptScore W2912579623C71924100 @default.
• W2912579623 hasConceptScore W2912579623C86803240 @default.
• W2912579623 hasConceptScore W2912579623C95190672 @default.
• W2912579623 hasLocation W29125796231 @default.
• W2912579623 hasLocation W29125796232 @default.
• W2912579623 hasOpenAccess W2912579623 @default.
• W2912579623 hasPrimaryLocation W29125796231 @default.
• W2912579623 hasRelatedWork W2027893081 @default.
• W2912579623 hasRelatedWork W2047252483 @default.
• W2912579623 hasRelatedWork W2074274808 @default.
• W2912579623 hasRelatedWork W2286371484 @default.
• W2912579623 hasRelatedWork W2318119155 @default.
• W2912579623 hasRelatedWork W2531052508 @default.

• next