Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912591199> ?p ?o ?g. }
- W2912591199 endingPage "56" @default.
- W2912591199 startingPage "49" @default.
- W2912591199 abstract "In this study, we report the development of a nanofiber polycaprolactone scaffold that can act as a stem cell carrier to induce chondrogenesis and promote cartilage repair in vivo. Infrapatellar fat pads were obtained from sheep knee and the stem cells were isolated and characterized by flow cytometry. Defects were created in sheep knee, two defects received adipose tissue derived stem cells (ASCs)-polycaprolactone construct, second group received polycaprolactone (PCL), the third group was chosen as the ASCs group and the fourth group was control group. Morphological evaluation showed that defects treated with ASCs-scaffold constructs were completely filled with cartilage-like tissue, while other groups revealed the formation of a thin layer of cartilage-like tissue in the defects. Real-Time RT-PCR showed the increase in collagen type 2 mRNA levels, aggrecan and Sox9 in ASCs/PCL groups in comparison with the other groups. Immunofluorescence and toluidine blue staining results showed the protein expression of collagen type 2 and formation of round and polygonal clusters of chondrocytes in ASCS/PCL group. According to our results nanofiber polycaprolactone promoted the chondrogenesis of infrapatellar adipose tissue derived stem cells in vivo and could offer significant promise in the biological functionality of stem cell tissue engineering in clinical practice." @default.
- W2912591199 created "2019-02-21" @default.
- W2912591199 creator A5017488210 @default.
- W2912591199 creator A5038115646 @default.
- W2912591199 creator A5041821699 @default.
- W2912591199 creator A5055145843 @default.
- W2912591199 creator A5062900263 @default.
- W2912591199 creator A5083185680 @default.
- W2912591199 date "2019-04-01" @default.
- W2912591199 modified "2023-09-27" @default.
- W2912591199 title "In vivo articular cartilage regeneration through infrapatellar adipose tissue derived stem cell in nanofiber polycaprolactone scaffold" @default.
- W2912591199 cites W139393056 @default.
- W2912591199 cites W1586130547 @default.
- W2912591199 cites W1928785183 @default.
- W2912591199 cites W2001547451 @default.
- W2912591199 cites W2007845729 @default.
- W2912591199 cites W2018042616 @default.
- W2912591199 cites W2021219047 @default.
- W2912591199 cites W2021842516 @default.
- W2912591199 cites W2035209595 @default.
- W2912591199 cites W2051272245 @default.
- W2912591199 cites W2086728480 @default.
- W2912591199 cites W2115324900 @default.
- W2912591199 cites W2121045985 @default.
- W2912591199 cites W2170089982 @default.
- W2912591199 cites W2204551059 @default.
- W2912591199 cites W2309305101 @default.
- W2912591199 cites W2326377876 @default.
- W2912591199 cites W247435333 @default.
- W2912591199 cites W2522638322 @default.
- W2912591199 cites W2523016801 @default.
- W2912591199 cites W2529795296 @default.
- W2912591199 cites W2556426145 @default.
- W2912591199 cites W2581465341 @default.
- W2912591199 cites W2587205266 @default.
- W2912591199 cites W2743506459 @default.
- W2912591199 cites W2746142322 @default.
- W2912591199 cites W2755319893 @default.
- W2912591199 cites W2758814689 @default.
- W2912591199 cites W2770502881 @default.
- W2912591199 cites W2778813663 @default.
- W2912591199 cites W2795709506 @default.
- W2912591199 cites W2799552254 @default.
- W2912591199 cites W2887144635 @default.
- W2912591199 doi "https://doi.org/10.1016/j.tice.2019.02.002" @default.
- W2912591199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30947963" @default.
- W2912591199 hasPublicationYear "2019" @default.
- W2912591199 type Work @default.
- W2912591199 sameAs 2912591199 @default.
- W2912591199 citedByCount "24" @default.
- W2912591199 countsByYear W29125911992019 @default.
- W2912591199 countsByYear W29125911992020 @default.
- W2912591199 countsByYear W29125911992021 @default.
- W2912591199 countsByYear W29125911992022 @default.
- W2912591199 countsByYear W29125911992023 @default.
- W2912591199 crossrefType "journal-article" @default.
- W2912591199 hasAuthorship W2912591199A5017488210 @default.
- W2912591199 hasAuthorship W2912591199A5038115646 @default.
- W2912591199 hasAuthorship W2912591199A5041821699 @default.
- W2912591199 hasAuthorship W2912591199A5055145843 @default.
- W2912591199 hasAuthorship W2912591199A5062900263 @default.
- W2912591199 hasAuthorship W2912591199A5083185680 @default.
- W2912591199 hasConcept C104317684 @default.
- W2912591199 hasConcept C105702510 @default.
- W2912591199 hasConcept C134018914 @default.
- W2912591199 hasConcept C136229726 @default.
- W2912591199 hasConcept C142724271 @default.
- W2912591199 hasConcept C150194340 @default.
- W2912591199 hasConcept C159985019 @default.
- W2912591199 hasConcept C171056886 @default.
- W2912591199 hasConcept C171089720 @default.
- W2912591199 hasConcept C192562407 @default.
- W2912591199 hasConcept C197534660 @default.
- W2912591199 hasConcept C204787440 @default.
- W2912591199 hasConcept C2776164576 @default.
- W2912591199 hasConcept C2776610510 @default.
- W2912591199 hasConcept C2778486617 @default.
- W2912591199 hasConcept C2779868350 @default.
- W2912591199 hasConcept C2780550940 @default.
- W2912591199 hasConcept C28328180 @default.
- W2912591199 hasConcept C3020332539 @default.
- W2912591199 hasConcept C35496256 @default.
- W2912591199 hasConcept C49892992 @default.
- W2912591199 hasConcept C521977710 @default.
- W2912591199 hasConcept C55493867 @default.
- W2912591199 hasConcept C71924100 @default.
- W2912591199 hasConcept C86803240 @default.
- W2912591199 hasConcept C89429830 @default.
- W2912591199 hasConcept C95444343 @default.
- W2912591199 hasConceptScore W2912591199C104317684 @default.
- W2912591199 hasConceptScore W2912591199C105702510 @default.
- W2912591199 hasConceptScore W2912591199C134018914 @default.
- W2912591199 hasConceptScore W2912591199C136229726 @default.
- W2912591199 hasConceptScore W2912591199C142724271 @default.
- W2912591199 hasConceptScore W2912591199C150194340 @default.
- W2912591199 hasConceptScore W2912591199C159985019 @default.
- W2912591199 hasConceptScore W2912591199C171056886 @default.
- W2912591199 hasConceptScore W2912591199C171089720 @default.