Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912598643> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2912598643 endingPage "2" @default.
- W2912598643 startingPage "1" @default.
- W2912598643 abstract "Coronavirus disease 2019 (COVID-19) is a rapidly evolving infectious/inflammatory disorder which has turned into a global pandemic. With severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as its etiologic agent, severe COVID-19 cases usually develop uncontrolled inflammatory responses and cytokine storm-like syndromes. Measuring serum levels of pro-inflammatory cytokines (e.g., IL-6 and others) as inflammatory biomarkers may have several potential applications in the management of COVID-19, including risk assessment, monitoring of disease progression, determination of prognosis, selection of therapy and prediction of response to treatment. This is especially true for pediatric patients with COVID-19 associated Kawasaki-like disease and similar syndromes. In this report, we review the current knowledge of COVID-19 associated cytokines, their roles in host immune and inflammatory responses, the clinical significance and utility of cytokine immunoassays in adult and pediatric COVID-19 patients, as well as the challenges and pitfalls in implementation and interpretation of cytokine immunoassays. Given that cytokines are implicated in different immunological disorders and diseases, it is challenging to interpret the multiplex cytokine data for COVID-19 patients. Also, it should be taken into consideration that biological and technical variables may affect the commutability of cytokine immunoassays and enhance complexity of cytokine immunoassay interpretation. It is recommended that the same method, platform and laboratory should be used when monitoring differences in cytokine levels between groups of individuals or for the same individual over time. It may be important to correlate cytokine profiling data with the SARS-CoV-2 nucleic acid amplification testing and imaging observations to make an accurate interpretation of the inflammatory status and disease progression in COVID-19 patients." @default.
- W2912598643 created "2019-02-21" @default.
- W2912598643 creator A5063673485 @default.
- W2912598643 date "2019-06-01" @default.
- W2912598643 modified "2023-09-25" @default.
- W2912598643 title "The “Yin-Yang” of cytokines in cancer" @default.
- W2912598643 cites W1498187417 @default.
- W2912598643 cites W1904332237 @default.
- W2912598643 cites W1973454407 @default.
- W2912598643 cites W1992088744 @default.
- W2912598643 cites W2030917941 @default.
- W2912598643 cites W2037038224 @default.
- W2912598643 cites W2056171219 @default.
- W2912598643 cites W2117692326 @default.
- W2912598643 cites W2143772132 @default.
- W2912598643 cites W2145592472 @default.
- W2912598643 cites W2168631000 @default.
- W2912598643 cites W2314851760 @default.
- W2912598643 cites W259732519 @default.
- W2912598643 cites W2783337717 @default.
- W2912598643 cites W2803721679 @default.
- W2912598643 cites W2891497275 @default.
- W2912598643 cites W2893631054 @default.
- W2912598643 doi "https://doi.org/10.1016/j.cyto.2018.12.013" @default.
- W2912598643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30712967" @default.
- W2912598643 hasPublicationYear "2019" @default.
- W2912598643 type Work @default.
- W2912598643 sameAs 2912598643 @default.
- W2912598643 citedByCount "5" @default.
- W2912598643 countsByYear W29125986432020 @default.
- W2912598643 countsByYear W29125986432021 @default.
- W2912598643 countsByYear W29125986432022 @default.
- W2912598643 crossrefType "journal-article" @default.
- W2912598643 hasAuthorship W2912598643A5063673485 @default.
- W2912598643 hasConcept C126322002 @default.
- W2912598643 hasConcept C203014093 @default.
- W2912598643 hasConcept C2777648638 @default.
- W2912598643 hasConcept C2778690821 @default.
- W2912598643 hasConcept C2779134260 @default.
- W2912598643 hasConcept C2779559532 @default.
- W2912598643 hasConcept C2781188995 @default.
- W2912598643 hasConcept C3008058167 @default.
- W2912598643 hasConcept C524204448 @default.
- W2912598643 hasConcept C60644358 @default.
- W2912598643 hasConcept C71924100 @default.
- W2912598643 hasConcept C86803240 @default.
- W2912598643 hasConcept C8891405 @default.
- W2912598643 hasConceptScore W2912598643C126322002 @default.
- W2912598643 hasConceptScore W2912598643C203014093 @default.
- W2912598643 hasConceptScore W2912598643C2777648638 @default.
- W2912598643 hasConceptScore W2912598643C2778690821 @default.
- W2912598643 hasConceptScore W2912598643C2779134260 @default.
- W2912598643 hasConceptScore W2912598643C2779559532 @default.
- W2912598643 hasConceptScore W2912598643C2781188995 @default.
- W2912598643 hasConceptScore W2912598643C3008058167 @default.
- W2912598643 hasConceptScore W2912598643C524204448 @default.
- W2912598643 hasConceptScore W2912598643C60644358 @default.
- W2912598643 hasConceptScore W2912598643C71924100 @default.
- W2912598643 hasConceptScore W2912598643C86803240 @default.
- W2912598643 hasConceptScore W2912598643C8891405 @default.
- W2912598643 hasLocation W29125986431 @default.
- W2912598643 hasLocation W29125986432 @default.
- W2912598643 hasOpenAccess W2912598643 @default.
- W2912598643 hasPrimaryLocation W29125986431 @default.
- W2912598643 hasRelatedWork W2047209980 @default.
- W2912598643 hasRelatedWork W3033207828 @default.
- W2912598643 hasRelatedWork W3087947088 @default.
- W2912598643 hasRelatedWork W3094204308 @default.
- W2912598643 hasRelatedWork W3135921613 @default.
- W2912598643 hasRelatedWork W3160595368 @default.
- W2912598643 hasRelatedWork W4205132829 @default.
- W2912598643 hasRelatedWork W4285131826 @default.
- W2912598643 hasRelatedWork W4307373393 @default.
- W2912598643 hasRelatedWork W4366998583 @default.
- W2912598643 hasVolume "118" @default.
- W2912598643 isParatext "false" @default.
- W2912598643 isRetracted "false" @default.
- W2912598643 magId "2912598643" @default.
- W2912598643 workType "article" @default.