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• W2912607684 abstract "The EPA/NIEHS Children’s Environmental Health and Disease Prevention Research Centers: More Than 15 Years of Innovative Research on Important Challenges in Children’s Environmental HealthAbstract Number:2798 Kimberly Gray* and Nica Louie* Kimberly Gray* U.S. Environmental Protection Agency, United States, E-mail Address: [email protected] Search for more papers by this author and Nica Louie* U.S. Environmental Protection Agency, United States, E-mail Address: [email protected] Search for more papers by this author AbstractBackground: The U.S. Environmental Protection Agency (EPA) and the National Institute of Environmental Health Sciences (NIEHS) have jointly supported the Children's Environmental Health and Disease Prevention Research Centers (‘Children’s Centers’) program since 1998, forming a highly successful and collaborative, interdisciplinary research network.Methods: These multidisciplinary, translational research centers are investigating the role of a wide range of environmental exposures in adverse children's health outcomes and how to protect children's health. Studies include how exposure to chemicals such as ambient air pollutants, arsenic in water and food, endocrine-disrupting compounds (EDCs) including bisphenol A (BPA), manganese, organophosphate pesticides and polybrominated flame retardants may, in combination with other factors such as social and behavioral factors and genetic susceptibility, result in adverse birth and health outcomes including asthma, autism, childhood leukemia, changes in epigenetics/gene expression, changes in neurodevelopment and immune system function -- and how to prevent adverse health outcomes. The Children's Centers are using approaches including longitudinal cohort and case-control studies and environmental epidemiology in conjunction with laboratory-based studies to find novel biomarkers of exposure, early developmental and pubertal effects and gene-environment interactions. Community engagement is a key part of the program.Results: This presentation will review some of the important findings from the program over the past 15 years and summarize some of the research currently being funded.Conclusion: Program grantees have published over 1,000 peer-reviewed publications, some highly cited in high-impact journals and cited in environmental policy. Research from the EPA/NIEHS Children’s Centers program is having a significant impact on the field of children’s environmental health and in protecting children's health." @default.
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• W2912607684 title "The EPA/NIEHS Children’s Environmental Health and Disease Prevention Research Centers: More Than 15 Years of Innovative Research on Important Challenges in Children’s Environmental Health" @default.
• W2912607684 doi "https://doi.org/10.1289/isee.2014.p3-666" @default.
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