Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912621545> ?p ?o ?g. }
- W2912621545 endingPage "171" @default.
- W2912621545 startingPage "159" @default.
- W2912621545 abstract "Severe community-acquired pneumonia (SCAP) is still associated with substantial morbidity and mortality. In this point-of-view review paper, a group of experts discuss the main controversies in SCAP: the role of severity scores to guide patient settings of care and empiric antibiotic therapy; the emergence of pathogens outside the core microorganisms of CAP; viral SCAP; the best empirical treatment; septic shock as the most lethal complication; and the need for new antibiotics.For all topics, the authors describe current controversies and evidence and provide recommendations and suggestions for future research. Evidence was based on meta-analyses, most recent RCTs and recent interventional or observational studies. Recommendations were reached by consensus of all the authors.The IDSA/ATS criteria remain the most pragmatic tool to predict ICU admission. The authors recommend a combination of a beta-lactam/beta-lactamase inhibitor or a third G cephalosporin plus a macrolide in most SCAP patients, and to empirically cover PES (P. aeruginosa, extended spectrum beta-lactamase producing Enterobacteriaceae, methicillin-resistant S. aureus) pathogens when at least two specific risk factors are present. In patients with influenza CAP, the authors recommend the use of oseltamivir and avoidance of the use of steroids. Corticosteroids can be used in case of refractory shock and high systemic inflammatory response." @default.
- W2912621545 created "2019-02-21" @default.
- W2912621545 creator A5016891336 @default.
- W2912621545 creator A5018936151 @default.
- W2912621545 creator A5022407641 @default.
- W2912621545 creator A5026604447 @default.
- W2912621545 creator A5034004394 @default.
- W2912621545 creator A5040669754 @default.
- W2912621545 creator A5056681502 @default.
- W2912621545 creator A5058271539 @default.
- W2912621545 date "2019-01-31" @default.
- W2912621545 modified "2023-10-10" @default.
- W2912621545 title "Challenges in severe community-acquired pneumonia: a point-of-view review" @default.
- W2912621545 cites W1693866076 @default.
- W2912621545 cites W1748070847 @default.
- W2912621545 cites W1761204585 @default.
- W2912621545 cites W1933982123 @default.
- W2912621545 cites W1967624425 @default.
- W2912621545 cites W1982251428 @default.
- W2912621545 cites W1988941701 @default.
- W2912621545 cites W1994533119 @default.
- W2912621545 cites W2000714505 @default.
- W2912621545 cites W2001245610 @default.
- W2912621545 cites W2023574001 @default.
- W2912621545 cites W2040052393 @default.
- W2912621545 cites W2040214782 @default.
- W2912621545 cites W2042944880 @default.
- W2912621545 cites W2052712852 @default.
- W2912621545 cites W2063994252 @default.
- W2912621545 cites W2078520647 @default.
- W2912621545 cites W2091139031 @default.
- W2912621545 cites W2091686466 @default.
- W2912621545 cites W2092545077 @default.
- W2912621545 cites W2094420308 @default.
- W2912621545 cites W2094857325 @default.
- W2912621545 cites W2101579685 @default.
- W2912621545 cites W2103199613 @default.
- W2912621545 cites W2105870958 @default.
- W2912621545 cites W2111085857 @default.
- W2912621545 cites W2112151341 @default.
- W2912621545 cites W2113535256 @default.
- W2912621545 cites W2117187812 @default.
- W2912621545 cites W2121617808 @default.
- W2912621545 cites W2122256368 @default.
- W2912621545 cites W2129705979 @default.
- W2912621545 cites W2130956494 @default.
- W2912621545 cites W2132212568 @default.
- W2912621545 cites W2133008785 @default.
- W2912621545 cites W2133979383 @default.
- W2912621545 cites W2136615242 @default.
- W2912621545 cites W2142413409 @default.
- W2912621545 cites W2150772812 @default.
- W2912621545 cites W2156236700 @default.
- W2912621545 cites W2161780492 @default.
- W2912621545 cites W2171284117 @default.
- W2912621545 cites W2185366655 @default.
- W2912621545 cites W2191831703 @default.
- W2912621545 cites W2194171205 @default.
- W2912621545 cites W2230717049 @default.
- W2912621545 cites W2255716754 @default.
- W2912621545 cites W2322024918 @default.
- W2912621545 cites W2345894311 @default.
- W2912621545 cites W2412668936 @default.
- W2912621545 cites W2514842683 @default.
- W2912621545 cites W2521215694 @default.
- W2912621545 cites W2528694892 @default.
- W2912621545 cites W2528956578 @default.
- W2912621545 cites W2531310538 @default.
- W2912621545 cites W2544208140 @default.
- W2912621545 cites W2550507245 @default.
- W2912621545 cites W2554492126 @default.
- W2912621545 cites W2556299404 @default.
- W2912621545 cites W2563657286 @default.
- W2912621545 cites W2575638356 @default.
- W2912621545 cites W2586291022 @default.
- W2912621545 cites W2589887932 @default.
- W2912621545 cites W2599659627 @default.
- W2912621545 cites W2603453044 @default.
- W2912621545 cites W2621952051 @default.
- W2912621545 cites W2622233354 @default.
- W2912621545 cites W2626617788 @default.
- W2912621545 cites W2727146855 @default.
- W2912621545 cites W2734776807 @default.
- W2912621545 cites W2735995416 @default.
- W2912621545 cites W2737660126 @default.
- W2912621545 cites W2753891190 @default.
- W2912621545 cites W2762679961 @default.
- W2912621545 cites W2769213252 @default.
- W2912621545 cites W2772386878 @default.
- W2912621545 cites W2783978675 @default.
- W2912621545 cites W2784412824 @default.
- W2912621545 cites W2791373299 @default.
- W2912621545 cites W2792243788 @default.
- W2912621545 cites W2792951614 @default.
- W2912621545 cites W2794125559 @default.
- W2912621545 cites W2795243898 @default.
- W2912621545 cites W2807550063 @default.
- W2912621545 cites W2810082193 @default.