FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W291264158> ?p ?o ?g. }

• W291264158 abstract "Cellular regulatory dynamics is driven by large and intricate networks of interactions at the molecular scale, whose sheer size obfuscates understanding. In light of limited experimental data, many parameters of such dynamics are unknown, and thus models built on the detailed, mechanistic viewpoint overfit and are not predictive. At the other extreme, simple ad hoc models of complex processes often miss defining features of the underlying systems. Here we propose an approach that instead constructs phenomenological, coarse-grained models of network dynamics that automatically adapt their complexity to the amount of available data. Such adaptive models lead to accurate predictions even when microscopic details of the studied systems are unknown due to insufficient data. The approach is computationally tractable, even for a relatively large number of dynamical variables, allowing its software realization, named Sir Isaac, to make successful predictions even when important dynamic variables are unobserved. For example, it matches the known phase space structure for simulated planetary motion data, avoids overfitting in a complex biological signaling system, and produces accurate predictions for a yeast glycolysis model with only tens of data points and over half of the interacting species unobserved." @default.
• W291264158 created "2016-06-24" @default.
• W291264158 creator A5008120275 @default.
• W291264158 creator A5071388278 @default.
• W291264158 date "2014-04-24" @default.
• W291264158 modified "2023-09-27" @default.
• W291264158 title "Automated adaptive inference of coarse-grained dynamical models in systems biology" @default.
• W291264158 cites W133148819 @default.
• W291264158 cites W1498436455 @default.
• W291264158 cites W1556089959 @default.
• W291264158 cites W1893491260 @default.
• W291264158 cites W1979769287 @default.
• W291264158 cites W1984391316 @default.
• W291264158 cites W2000040887 @default.
• W291264158 cites W2004385216 @default.
• W291264158 cites W2016803695 @default.
• W291264158 cites W2021058886 @default.
• W291264158 cites W2032535902 @default.
• W291264158 cites W2041132213 @default.
• W291264158 cites W2041951716 @default.
• W291264158 cites W2043487490 @default.
• W291264158 cites W2044784465 @default.
• W291264158 cites W2046042332 @default.
• W291264158 cites W2056961883 @default.
• W291264158 cites W2058580716 @default.
• W291264158 cites W2069647329 @default.
• W291264158 cites W2069941324 @default.
• W291264158 cites W2081240630 @default.
• W291264158 cites W2087636279 @default.
• W291264158 cites W2099231026 @default.
• W291264158 cites W2104649539 @default.
• W291264158 cites W2111270167 @default.
• W291264158 cites W2111936337 @default.
• W291264158 cites W2117663940 @default.
• W291264158 cites W2122234510 @default.
• W291264158 cites W2124641450 @default.
• W291264158 cites W2128957129 @default.
• W291264158 cites W2143970285 @default.
• W291264158 cites W2149695944 @default.
• W291264158 cites W2151554678 @default.
• W291264158 cites W2156909104 @default.
• W291264158 cites W2161304688 @default.
• W291264158 cites W2168175751 @default.
• W291264158 cites W2246296081 @default.
• W291264158 cites W3098928821 @default.
• W291264158 cites W3140968660 @default.
• W291264158 hasPublicationYear "2014" @default.
• W291264158 type Work @default.
• W291264158 sameAs 291264158 @default.
• W291264158 citedByCount "1" @default.
• W291264158 countsByYear W2912641582019 @default.
• W291264158 crossrefType "posted-content" @default.
• W291264158 hasAuthorship W291264158A5008120275 @default.
• W291264158 hasAuthorship W291264158A5071388278 @default.
• W291264158 hasConcept C105795698 @default.
• W291264158 hasConcept C111472728 @default.
• W291264158 hasConcept C119857082 @default.
• W291264158 hasConcept C121332964 @default.
• W291264158 hasConcept C138885662 @default.
• W291264158 hasConcept C152662350 @default.
• W291264158 hasConcept C154945302 @default.
• W291264158 hasConcept C22019652 @default.
• W291264158 hasConcept C2776214188 @default.
• W291264158 hasConcept C2780586882 @default.
• W291264158 hasConcept C2781089630 @default.
• W291264158 hasConcept C33923547 @default.
• W291264158 hasConcept C41008148 @default.
• W291264158 hasConcept C47822265 @default.
• W291264158 hasConcept C50644808 @default.
• W291264158 hasConcept C60644358 @default.
• W291264158 hasConcept C62520636 @default.
• W291264158 hasConcept C79379906 @default.
• W291264158 hasConcept C80444323 @default.
• W291264158 hasConcept C86803240 @default.
• W291264158 hasConceptScore W291264158C105795698 @default.
• W291264158 hasConceptScore W291264158C111472728 @default.
• W291264158 hasConceptScore W291264158C119857082 @default.
• W291264158 hasConceptScore W291264158C121332964 @default.
• W291264158 hasConceptScore W291264158C138885662 @default.
• W291264158 hasConceptScore W291264158C152662350 @default.
• W291264158 hasConceptScore W291264158C154945302 @default.
• W291264158 hasConceptScore W291264158C22019652 @default.
• W291264158 hasConceptScore W291264158C2776214188 @default.
• W291264158 hasConceptScore W291264158C2780586882 @default.
• W291264158 hasConceptScore W291264158C2781089630 @default.
• W291264158 hasConceptScore W291264158C33923547 @default.
• W291264158 hasConceptScore W291264158C41008148 @default.
• W291264158 hasConceptScore W291264158C47822265 @default.
• W291264158 hasConceptScore W291264158C50644808 @default.
• W291264158 hasConceptScore W291264158C60644358 @default.
• W291264158 hasConceptScore W291264158C62520636 @default.
• W291264158 hasConceptScore W291264158C79379906 @default.
• W291264158 hasConceptScore W291264158C80444323 @default.
• W291264158 hasConceptScore W291264158C86803240 @default.
• W291264158 hasLocation W2912641581 @default.
• W291264158 hasOpenAccess W291264158 @default.
• W291264158 hasPrimaryLocation W2912641581 @default.
• W291264158 hasRelatedWork W1899045394 @default.
• W291264158 hasRelatedWork W1983030487 @default.
• W291264158 hasRelatedWork W2005979252 @default.

• next