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- W2912655098 abstract "Abstract Bioelectronic devices that modulate pH can affect critical biological processes including enzymatic activity, oxidative phosphorylation, and neuronal excitability. A major challenge in controlling pH is the high buffering capacity of many biological media. To overcome this challenge, devices need to be able to store and deliver a large number of protons on demand. Here, a bioelectronic modulator that controls pH using palladium nanoparticles contacts with high surface area as a proton storage medium is developed. Reversible electronically triggered acidosis (low pH) and alkalosis (high pH) in physiologically relevant buffer conditions are achieved. As a proof of principle, this new platform is used to control the degradation and fluorescence of acid sensitive polymeric microparticles loaded with a pH sensitive fluorescent dye." @default.
- W2912655098 created "2019-02-21" @default.
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- W2912655098 date "2019-01-28" @default.
- W2912655098 modified "2023-10-16" @default.
- W2912655098 title "A Bioelectronic Platform Modulates pH in Biologically Relevant Conditions" @default.
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- W2912655098 doi "https://doi.org/10.1002/advs.201800935" @default.
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