Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912659699> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2912659699 endingPage "97" @default.
- W2912659699 startingPage "91" @default.
- W2912659699 abstract "Background: The ABRA C-terminal like (ABRACL) protein belongs to a novel family of low-molecular weight proteins that increase actin dynamics and cell motility. It is involved in various diseases including cancer; however, its role in gastric cancer is unclear. In this study, the expression of ABRACL in gastric cancer and its relationships with patients' clinicopathological features and survival are examined. Methods: Sample expression profiles were downloaded from the Gene Expression Omnibus database and the Cancer Genome Atlas. ABRACL expression at the protein level in normal gastric and gastric cancer tissues was compared by using immunohistochemistry staining data provided by the Human Protein Atlas. Correlations between ABRACL expression and clinicopathological features are analyzed by chi-square tests. Patient survival was evaluated by Kaplan–Meier analysis. Results:ABRACL expression is upregulated in gastric cancer tissues than in normal tissues. High ABRACL levels indicated a poor prognosis. ABRACL expression (low ABRACL, n = 96; high ABRACL, n = 96) in gastric cancer tissues (primary data from GSE15459) is significantly correlated with poor overall survival (χ2 = 4.078, p = 0.043; log-rank test). ABRACL protein levels (low ABRACL, n = 172, high ABRACL, n = 171) in gastric cancer tissues (primary data from www.kmplot.com) are significantly correlated with poor overall survival (χ2 = 4.305, p = 0.038, log-rank test). Conclusions: Our results indicate that ABRACL is highly expressed in gastric cancer and is a potential prognostic marker and therapeutic target for this disease." @default.
- W2912659699 created "2019-02-21" @default.
- W2912659699 creator A5028063661 @default.
- W2912659699 creator A5059329180 @default.
- W2912659699 creator A5068952870 @default.
- W2912659699 creator A5079623224 @default.
- W2912659699 date "2019-02-01" @default.
- W2912659699 modified "2023-10-16" @default.
- W2912659699 title "High Expression of <i>ABRACL</i> Is Associated with Tumorigenesis and Affects Clinical Outcome in Gastric Cancer" @default.
- W2912659699 cites W1494567496 @default.
- W2912659699 cites W1535383246 @default.
- W2912659699 cites W1979760907 @default.
- W2912659699 cites W1985628988 @default.
- W2912659699 cites W2000241906 @default.
- W2912659699 cites W2020321814 @default.
- W2912659699 cites W2025192084 @default.
- W2912659699 cites W2033873142 @default.
- W2912659699 cites W2063959543 @default.
- W2912659699 cites W2106366706 @default.
- W2912659699 cites W2109521384 @default.
- W2912659699 cites W2122568296 @default.
- W2912659699 cites W2132403388 @default.
- W2912659699 cites W2139050844 @default.
- W2912659699 cites W2152578044 @default.
- W2912659699 cites W2153321977 @default.
- W2912659699 cites W2158146666 @default.
- W2912659699 cites W2166259946 @default.
- W2912659699 cites W2170989872 @default.
- W2912659699 cites W2275326785 @default.
- W2912659699 cites W2463600666 @default.
- W2912659699 cites W2616561367 @default.
- W2912659699 cites W2768272363 @default.
- W2912659699 cites W2768731253 @default.
- W2912659699 cites W2782982023 @default.
- W2912659699 cites W2803384724 @default.
- W2912659699 cites W308563075 @default.
- W2912659699 doi "https://doi.org/10.1089/gtmb.2018.0195" @default.
- W2912659699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30676103" @default.
- W2912659699 hasPublicationYear "2019" @default.
- W2912659699 type Work @default.
- W2912659699 sameAs 2912659699 @default.
- W2912659699 citedByCount "9" @default.
- W2912659699 countsByYear W29126596992020 @default.
- W2912659699 countsByYear W29126596992021 @default.
- W2912659699 countsByYear W29126596992022 @default.
- W2912659699 countsByYear W29126596992023 @default.
- W2912659699 crossrefType "journal-article" @default.
- W2912659699 hasAuthorship W2912659699A5028063661 @default.
- W2912659699 hasAuthorship W2912659699A5059329180 @default.
- W2912659699 hasAuthorship W2912659699A5068952870 @default.
- W2912659699 hasAuthorship W2912659699A5079623224 @default.
- W2912659699 hasConcept C104317684 @default.
- W2912659699 hasConcept C10515644 @default.
- W2912659699 hasConcept C121608353 @default.
- W2912659699 hasConcept C126322002 @default.
- W2912659699 hasConcept C142724271 @default.
- W2912659699 hasConcept C143998085 @default.
- W2912659699 hasConcept C158163496 @default.
- W2912659699 hasConcept C204232928 @default.
- W2912659699 hasConcept C502942594 @default.
- W2912659699 hasConcept C54355233 @default.
- W2912659699 hasConcept C555283112 @default.
- W2912659699 hasConcept C6856738 @default.
- W2912659699 hasConcept C71924100 @default.
- W2912659699 hasConcept C86803240 @default.
- W2912659699 hasConceptScore W2912659699C104317684 @default.
- W2912659699 hasConceptScore W2912659699C10515644 @default.
- W2912659699 hasConceptScore W2912659699C121608353 @default.
- W2912659699 hasConceptScore W2912659699C126322002 @default.
- W2912659699 hasConceptScore W2912659699C142724271 @default.
- W2912659699 hasConceptScore W2912659699C143998085 @default.
- W2912659699 hasConceptScore W2912659699C158163496 @default.
- W2912659699 hasConceptScore W2912659699C204232928 @default.
- W2912659699 hasConceptScore W2912659699C502942594 @default.
- W2912659699 hasConceptScore W2912659699C54355233 @default.
- W2912659699 hasConceptScore W2912659699C555283112 @default.
- W2912659699 hasConceptScore W2912659699C6856738 @default.
- W2912659699 hasConceptScore W2912659699C71924100 @default.
- W2912659699 hasConceptScore W2912659699C86803240 @default.
- W2912659699 hasIssue "2" @default.
- W2912659699 hasLocation W29126596991 @default.
- W2912659699 hasOpenAccess W2912659699 @default.
- W2912659699 hasPrimaryLocation W29126596991 @default.
- W2912659699 hasRelatedWork W1499339123 @default.
- W2912659699 hasRelatedWork W1553222881 @default.
- W2912659699 hasRelatedWork W2002500046 @default.
- W2912659699 hasRelatedWork W2055479802 @default.
- W2912659699 hasRelatedWork W2117059884 @default.
- W2912659699 hasRelatedWork W2464498936 @default.
- W2912659699 hasRelatedWork W3039417458 @default.
- W2912659699 hasRelatedWork W3119807610 @default.
- W2912659699 hasRelatedWork W4205990802 @default.
- W2912659699 hasRelatedWork W4323808922 @default.
- W2912659699 hasVolume "23" @default.
- W2912659699 isParatext "false" @default.
- W2912659699 isRetracted "false" @default.
- W2912659699 magId "2912659699" @default.
- W2912659699 workType "article" @default.