FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912666851> ?p ?o ?g. }

• W2912666851 endingPage "371" @default.
• W2912666851 startingPage "359" @default.
• W2912666851 abstract "Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) is one of the main antimicrobial-resistant pathogens. Little data are available on how biofilm formation (BF) contributes to EC-caused bloodstream infection (BSI) in cancer patients. This study investigated the impact of BF on clinical outcomes of cancer patients with EC-caused BSI.Clinical outcome and microbiological characteristics including the presence of bla genes in ESBL-EC isolates were retrospectively collected from BSI cancer patients. Patients infected with ESBL-EC were compared with patients infected with third-generation cephalosporin-susceptible strains. Survival curves were generated by Kaplan-Meier analysis and the survival difference was assessed by the log-rank test. Risk factors for ESBL-EC infection, predictors of mortality, and outcome differences were determined by multivariate logistic regression and Cox regression analysis, respectively.A high prevalence of ESBL-EC with dominant blaCTX-M-15, blaCTX-M-15 plus blaTEM-52 genotype was found in BSI cancer patients. Independent risk factors for infection with ESBL-EC were cephalosporins, chemotherapy, and BF. Metastasis, ICU admission, BF-positive ESBL-EC, organ failure, and the presence of septic shock were revealed as predictors for mortality. The ESBL characteristic was associated with the BF phenotype, and the overall mortality was significantly higher in cancer patients with BF-positive ESBL-EC-caused BSI.blaCTX-M-15 type ESBL-EC is highly endemic among cancer patients with BSI. BF is associated with multi-drug resistance by ESBL-EC and is also an independent risk factor of mortality for cancer patients with BSI. Our findings suggest that the combination of BF-positive ESBL-EC isolates with other appropriate laboratory indicators might benefit infection control and improve clinical outcomes." @default.
• W2912666851 created "2019-02-21" @default.
• W2912666851 creator A5000614413 @default.
• W2912666851 creator A5009480635 @default.
• W2912666851 creator A5022687764 @default.
• W2912666851 creator A5032549492 @default.
• W2912666851 creator A5041241770 @default.
• W2912666851 creator A5045585039 @default.
• W2912666851 creator A5078605887 @default.
• W2912666851 creator A5078738164 @default.
• W2912666851 date "2019-02-01" @default.
• W2912666851 modified "2023-10-11" @default.
• W2912666851 title "<p>Clinical outcome of <em>Escherichia coli</em> bloodstream infection in cancer patients with/without biofilm formation: a single-center retrospective study</p>" @default.
• W2912666851 cites W163248615 @default.
• W2912666851 cites W1960109612 @default.
• W2912666851 cites W1979616917 @default.
• W2912666851 cites W1996958990 @default.
• W2912666851 cites W2001838110 @default.
• W2912666851 cites W2021335173 @default.
• W2912666851 cites W2025953236 @default.
• W2912666851 cites W2062374558 @default.
• W2912666851 cites W2099528852 @default.
• W2912666851 cites W2108864681 @default.
• W2912666851 cites W2117520981 @default.
• W2912666851 cites W2122721391 @default.
• W2912666851 cites W2124635476 @default.
• W2912666851 cites W2124718251 @default.
• W2912666851 cites W2138309877 @default.
• W2912666851 cites W2144298692 @default.
• W2912666851 cites W2144440398 @default.
• W2912666851 cites W2154007902 @default.
• W2912666851 cites W2163943620 @default.
• W2912666851 cites W2165905525 @default.
• W2912666851 cites W2168142063 @default.
• W2912666851 cites W2169047822 @default.
• W2912666851 cites W2171677875 @default.
• W2912666851 cites W2171977772 @default.
• W2912666851 cites W2277200478 @default.
• W2912666851 cites W2298346855 @default.
• W2912666851 cites W2327571891 @default.
• W2912666851 cites W2334971494 @default.
• W2912666851 cites W2567027391 @default.
• W2912666851 cites W2606062326 @default.
• W2912666851 cites W2762856397 @default.
• W2912666851 cites W2768146862 @default.
• W2912666851 doi "https://doi.org/10.2147/idr.s192072" @default.
• W2912666851 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6377049" @default.
• W2912666851 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30809097" @default.
• W2912666851 hasPublicationYear "2019" @default.
• W2912666851 type Work @default.
• W2912666851 sameAs 2912666851 @default.
• W2912666851 citedByCount "17" @default.
• W2912666851 countsByYear W29126668512020 @default.
• W2912666851 countsByYear W29126668512021 @default.
• W2912666851 countsByYear W29126668512022 @default.
• W2912666851 countsByYear W29126668512023 @default.
• W2912666851 crossrefType "journal-article" @default.
• W2912666851 hasAuthorship W2912666851A5000614413 @default.
• W2912666851 hasAuthorship W2912666851A5009480635 @default.
• W2912666851 hasAuthorship W2912666851A5022687764 @default.
• W2912666851 hasAuthorship W2912666851A5032549492 @default.
• W2912666851 hasAuthorship W2912666851A5041241770 @default.
• W2912666851 hasAuthorship W2912666851A5045585039 @default.
• W2912666851 hasAuthorship W2912666851A5078605887 @default.
• W2912666851 hasAuthorship W2912666851A5078738164 @default.
• W2912666851 hasBestOaLocation W29126668511 @default.
• W2912666851 hasConcept C121608353 @default.
• W2912666851 hasConcept C126322002 @default.
• W2912666851 hasConcept C151956035 @default.
• W2912666851 hasConcept C167135981 @default.
• W2912666851 hasConcept C2777628635 @default.
• W2912666851 hasConcept C2778384902 @default.
• W2912666851 hasConcept C3018946976 @default.
• W2912666851 hasConcept C4937899 @default.
• W2912666851 hasConcept C501593827 @default.
• W2912666851 hasConcept C50382708 @default.
• W2912666851 hasConcept C64778159 @default.
• W2912666851 hasConcept C71924100 @default.
• W2912666851 hasConcept C86803240 @default.
• W2912666851 hasConcept C89423630 @default.
• W2912666851 hasConcept C90924648 @default.
• W2912666851 hasConceptScore W2912666851C121608353 @default.
• W2912666851 hasConceptScore W2912666851C126322002 @default.
• W2912666851 hasConceptScore W2912666851C151956035 @default.
• W2912666851 hasConceptScore W2912666851C167135981 @default.
• W2912666851 hasConceptScore W2912666851C2777628635 @default.
• W2912666851 hasConceptScore W2912666851C2778384902 @default.
• W2912666851 hasConceptScore W2912666851C3018946976 @default.
• W2912666851 hasConceptScore W2912666851C4937899 @default.
• W2912666851 hasConceptScore W2912666851C501593827 @default.
• W2912666851 hasConceptScore W2912666851C50382708 @default.
• W2912666851 hasConceptScore W2912666851C64778159 @default.
• W2912666851 hasConceptScore W2912666851C71924100 @default.
• W2912666851 hasConceptScore W2912666851C86803240 @default.
• W2912666851 hasConceptScore W2912666851C89423630 @default.
• W2912666851 hasConceptScore W2912666851C90924648 @default.
• W2912666851 hasLocation W29126668511 @default.
• W2912666851 hasLocation W29126668512 @default.

• next