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- W2912673401 abstract "Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-care and community settings is also a leading cause of bacteraemia, endocarditis, skin and soft tissue infections, bone and joint infections and hospital-acquired infections. Genetically diverse, the epidemiology of MRSA is primarily characterized by the serial emergence of epidemic strains. Although its incidence has recently declined in some regions, MRSA still poses a formidable clinical threat, with persistently high morbidity and mortality. Successful treatment remains challenging and requires the evaluation of both novel antimicrobials and adjunctive aspects of care, such as infectious disease consultation, echocardiography and source control. In this Review, we provide an overview of basic and clinical MRSA research and summarize the expansive body of literature on the epidemiology, transmission, genetic diversity, evolution, surveillance and treatment of MRSA. Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen both within hospitals and in the community. In this Review, Fowler and colleagues provide an overview of basic and clinical MRSA research and explore the epidemiology, transmission, genetic diversity, evolution, surveillance and treatment of MRSA." @default.
- W2912673401 created "2019-02-21" @default.
- W2912673401 creator A5015117095 @default.
- W2912673401 creator A5018923507 @default.
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- W2912673401 creator A5045500368 @default.
- W2912673401 creator A5048912205 @default.
- W2912673401 creator A5057825659 @default.
- W2912673401 creator A5076959994 @default.
- W2912673401 date "2019-02-08" @default.
- W2912673401 modified "2023-10-18" @default.
- W2912673401 title "Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research" @default.
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