FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912676825> ?p ?o ?g. }

• W2912676825 endingPage "667" @default.
• W2912676825 startingPage "653" @default.
• W2912676825 abstract "Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated the potential prognostic role of autophagy‐associated long non‐coding RNA (lncRNA) in glioma patients. In this study, we obtained 879 lncRNAs and 216 autophagy genes from the Chinese Glioma Genome Atlas microarray, and found that 402 lncRNAs are correlated with the autophagy genes. Subsequently, 10 autophagy‐associated lncRNAs with prognostic value ( PCBP1‐AS1 , TP53TG1 , DHRS4‐AS1 , ZNF674‐AS1 , GABPB1‐AS1 , DDX11‐AS1 , SBF2‐AS1 , MIR4453HG , MAPKAPK5 ‐AS1 and COX10‐AS1 ) were identified in glioma patients using multivariate Cox regression analyses. A prognostic signature was then established based on these prognostic lncRNAs, dividing patients into low‐risk and high‐risk groups. The overall survival time was shorter in the high‐risk group than that in the low‐risk group [hazard ratio (HR) = 5.307, 95% CI: 4.195–8.305; P < 0.0001]. Gene set enrichment analysis revealed that the gene sets were significantly enriched in cancer‐related pathways, including interleukin (IL) 6/Janus kinase/signal transducer and activator of transcription (STAT) 3 signaling, tumor necrosis factor α signaling via nuclear factor κB, IL2/STAT5 signaling, the p53 pathway and the KRAS signaling pathway. The Cancer Genome Atlas dataset was used to validate that high‐risk patients have worse survival outcomes than low‐risk patients (HR = 1.544, 95% CI: 1.110–2.231; P = 0.031). In summary, our signature of 10 autophagy‐related lncRNAs has prognostic potential for glioma, and these autophagy‐related lncRNAs may play a key role in glioma biology." @default.
• W2912676825 created "2019-02-21" @default.
• W2912676825 creator A5013219878 @default.
• W2912676825 creator A5016853386 @default.
• W2912676825 creator A5017641593 @default.
• W2912676825 creator A5022499603 @default.
• W2912676825 creator A5039896971 @default.
• W2912676825 creator A5058001588 @default.
• W2912676825 creator A5088002325 @default.
• W2912676825 creator A5091105534 @default.
• W2912676825 date "2019-03-05" @default.
• W2912676825 modified "2023-10-12" @default.
• W2912676825 title "An autophagy‐related long non‐coding RNA signature for glioma" @default.
• W2912676825 cites W1523693806 @default.
• W2912676825 cites W1576461546 @default.
• W2912676825 cites W1719678457 @default.
• W2912676825 cites W1893588436 @default.
• W2912676825 cites W1996593753 @default.
• W2912676825 cites W2007121176 @default.
• W2912676825 cites W2031572048 @default.
• W2912676825 cites W2040827479 @default.
• W2912676825 cites W2048030072 @default.
• W2912676825 cites W2050574817 @default.
• W2912676825 cites W2063096082 @default.
• W2912676825 cites W2075996288 @default.
• W2912676825 cites W2079351077 @default.
• W2912676825 cites W2084946596 @default.
• W2912676825 cites W2087377443 @default.
• W2912676825 cites W2089074573 @default.
• W2912676825 cites W2092543281 @default.
• W2912676825 cites W2099551830 @default.
• W2912676825 cites W2104381422 @default.
• W2912676825 cites W2109034822 @default.
• W2912676825 cites W2150638747 @default.
• W2912676825 cites W2159355549 @default.
• W2912676825 cites W2159675211 @default.
• W2912676825 cites W2160382843 @default.
• W2912676825 cites W2178988142 @default.
• W2912676825 cites W2259090596 @default.
• W2912676825 cites W2399977168 @default.
• W2912676825 cites W2409062259 @default.
• W2912676825 cites W2490184101 @default.
• W2912676825 cites W2524206229 @default.
• W2912676825 cites W2535995771 @default.
• W2912676825 cites W2565822896 @default.
• W2912676825 cites W2595012919 @default.
• W2912676825 cites W2600434382 @default.
• W2912676825 cites W2620962827 @default.
• W2912676825 cites W2748551035 @default.
• W2912676825 cites W2767695858 @default.
• W2912676825 cites W2800469107 @default.
• W2912676825 cites W964275744 @default.
• W2912676825 doi "https://doi.org/10.1002/2211-5463.12601" @default.
• W2912676825 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6443865" @default.
• W2912676825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30984540" @default.
• W2912676825 hasPublicationYear "2019" @default.
• W2912676825 type Work @default.
• W2912676825 sameAs 2912676825 @default.
• W2912676825 citedByCount "79" @default.
• W2912676825 countsByYear W29126768252020 @default.
• W2912676825 countsByYear W29126768252021 @default.
• W2912676825 countsByYear W29126768252022 @default.
• W2912676825 countsByYear W29126768252023 @default.
• W2912676825 crossrefType "journal-article" @default.
• W2912676825 hasAuthorship W2912676825A5013219878 @default.
• W2912676825 hasAuthorship W2912676825A5016853386 @default.
• W2912676825 hasAuthorship W2912676825A5017641593 @default.
• W2912676825 hasAuthorship W2912676825A5022499603 @default.
• W2912676825 hasAuthorship W2912676825A5039896971 @default.
• W2912676825 hasAuthorship W2912676825A5058001588 @default.
• W2912676825 hasAuthorship W2912676825A5088002325 @default.
• W2912676825 hasAuthorship W2912676825A5091105534 @default.
• W2912676825 hasBestOaLocation W29126768251 @default.
• W2912676825 hasConcept C104317684 @default.
• W2912676825 hasConcept C126322002 @default.
• W2912676825 hasConcept C143998085 @default.
• W2912676825 hasConcept C150194340 @default.
• W2912676825 hasConcept C171958077 @default.
• W2912676825 hasConcept C190283241 @default.
• W2912676825 hasConcept C203522944 @default.
• W2912676825 hasConcept C207103383 @default.
• W2912676825 hasConcept C2778227246 @default.
• W2912676825 hasConcept C2778923194 @default.
• W2912676825 hasConcept C2779733811 @default.
• W2912676825 hasConcept C2781187634 @default.
• W2912676825 hasConcept C44249647 @default.
• W2912676825 hasConcept C501734568 @default.
• W2912676825 hasConcept C502942594 @default.
• W2912676825 hasConcept C54355233 @default.
• W2912676825 hasConcept C62203573 @default.
• W2912676825 hasConcept C67705224 @default.
• W2912676825 hasConcept C71924100 @default.
• W2912676825 hasConcept C86803240 @default.
• W2912676825 hasConceptScore W2912676825C104317684 @default.
• W2912676825 hasConceptScore W2912676825C126322002 @default.
• W2912676825 hasConceptScore W2912676825C143998085 @default.
• W2912676825 hasConceptScore W2912676825C150194340 @default.
• W2912676825 hasConceptScore W2912676825C171958077 @default.

• next