FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912677485> ?p ?o ?g. }

• W2912677485 endingPage "67" @default.
• W2912677485 startingPage "59" @default.
• W2912677485 abstract "The red-eared slider (Trachemys scripta elegans), a freshwater turtle, is an invasive species in many parts of the world where it survives in both freshwater and coastal saline habitats. High salinity can induce reactive oxygen species (ROS) production and lead to oxidative damage. In this study, we investigate the antioxidant defense mechanisms of T. s. elegans in response to salinity stress. The results showed that the mRNA expression levels of superoxide dismutase (SODs), catalase (CAT) and glutathione peroxidase (GSH-PXs) were significantly increased in both 5 psu and 15 psu groups at the early stages of salinity exposure (generally 6–48 h), but typically returned to control levels after the longest 30 d exposure. In addition, hepatic and cardiac mRNA levels of the NF-E2-related factor 2 (Nrf2), showed a similar upregulation as an early response to stress, but decreased at 30 d in the 5 psu and 15 psu groups. The mRNA levels of the negative regulator of Nrf2, kelch-like ECH associating protein 1 (Keap1), exhibited the opposite pattern. Moreover, mRNA expression levels of target of rapamycin (TOR) and ribosomal protein S6 kinase 1 (S6K1) in liver and heart showed roughly similar patterns to those for Nrf2. Furthermore, the content of malondialdehyde (MDA) was significantly increased in liver, especially in the 15 psu group by ~2.5-fold. Taken together, these results indicate that T. s. elegans may activate the TOR-Nrf2 pathway to modulate antioxidant genes transcription in order to promote enhanced antioxidant defense in response to salinity stress." @default.
• W2912677485 created "2019-02-21" @default.
• W2912677485 creator A5024739424 @default.
• W2912677485 creator A5031315906 @default.
• W2912677485 creator A5039598872 @default.
• W2912677485 creator A5043966211 @default.
• W2912677485 creator A5046421460 @default.
• W2912677485 creator A5051921751 @default.
• W2912677485 creator A5052195693 @default.
• W2912677485 creator A5071968823 @default.
• W2912677485 creator A5074785536 @default.
• W2912677485 date "2019-05-01" @default.
• W2912677485 modified "2023-10-16" @default.
• W2912677485 title "Antioxidant responses to salinity stress in an invasive species, the red-eared slider (Trachemys scripta elegans) and involvement of a TOR-Nrf2 signaling pathway" @default.
• W2912677485 cites W1231316025 @default.
• W2912677485 cites W1428907351 @default.
• W2912677485 cites W1785455093 @default.
• W2912677485 cites W1827553132 @default.
• W2912677485 cites W1917529770 @default.
• W2912677485 cites W1930402230 @default.
• W2912677485 cites W1964444610 @default.
• W2912677485 cites W1971732805 @default.
• W2912677485 cites W1977927760 @default.
• W2912677485 cites W1980686102 @default.
• W2912677485 cites W1987857240 @default.
• W2912677485 cites W1990670333 @default.
• W2912677485 cites W1991093645 @default.
• W2912677485 cites W1991653671 @default.
• W2912677485 cites W2002015567 @default.
• W2912677485 cites W2003962390 @default.
• W2912677485 cites W2004409713 @default.
• W2912677485 cites W2004793217 @default.
• W2912677485 cites W2010462885 @default.
• W2912677485 cites W2012611591 @default.
• W2912677485 cites W2015392958 @default.
• W2912677485 cites W2022848089 @default.
• W2912677485 cites W2027108612 @default.
• W2912677485 cites W2030019992 @default.
• W2912677485 cites W2042873751 @default.
• W2912677485 cites W2046832282 @default.
• W2912677485 cites W2059954771 @default.
• W2912677485 cites W2068102724 @default.
• W2912677485 cites W2071131953 @default.
• W2912677485 cites W2087695417 @default.
• W2912677485 cites W2089032508 @default.
• W2912677485 cites W2098562898 @default.
• W2912677485 cites W2100068043 @default.
• W2912677485 cites W2100896724 @default.
• W2912677485 cites W2104109524 @default.
• W2912677485 cites W2108565070 @default.
• W2912677485 cites W2119544175 @default.
• W2912677485 cites W2125202608 @default.
• W2912677485 cites W2134138119 @default.
• W2912677485 cites W2134996265 @default.
• W2912677485 cites W2138235906 @default.
• W2912677485 cites W2145390564 @default.
• W2912677485 cites W2150414404 @default.
• W2912677485 cites W2228708093 @default.
• W2912677485 cites W2338979602 @default.
• W2912677485 cites W2401441484 @default.
• W2912677485 cites W2486664877 @default.
• W2912677485 cites W2540781052 @default.
• W2912677485 cites W2548213466 @default.
• W2912677485 cites W2791517586 @default.
• W2912677485 doi "https://doi.org/10.1016/j.cbpc.2019.02.004" @default.
• W2912677485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30738853" @default.
• W2912677485 hasPublicationYear "2019" @default.
• W2912677485 type Work @default.
• W2912677485 sameAs 2912677485 @default.
• W2912677485 citedByCount "12" @default.
• W2912677485 countsByYear W29126774852019 @default.
• W2912677485 countsByYear W29126774852020 @default.
• W2912677485 countsByYear W29126774852021 @default.
• W2912677485 countsByYear W29126774852022 @default.
• W2912677485 countsByYear W29126774852023 @default.
• W2912677485 crossrefType "journal-article" @default.
• W2912677485 hasAuthorship W2912677485A5024739424 @default.
• W2912677485 hasAuthorship W2912677485A5031315906 @default.
• W2912677485 hasAuthorship W2912677485A5039598872 @default.
• W2912677485 hasAuthorship W2912677485A5043966211 @default.
• W2912677485 hasAuthorship W2912677485A5046421460 @default.
• W2912677485 hasAuthorship W2912677485A5051921751 @default.
• W2912677485 hasAuthorship W2912677485A5052195693 @default.
• W2912677485 hasAuthorship W2912677485A5071968823 @default.
• W2912677485 hasAuthorship W2912677485A5074785536 @default.
• W2912677485 hasConcept C104317684 @default.
• W2912677485 hasConcept C129513315 @default.
• W2912677485 hasConcept C181199279 @default.
• W2912677485 hasConcept C18903297 @default.
• W2912677485 hasConcept C2775838275 @default.
• W2912677485 hasConcept C2776151105 @default.
• W2912677485 hasConcept C2776529522 @default.
• W2912677485 hasConcept C2778004101 @default.
• W2912677485 hasConcept C2778401633 @default.
• W2912677485 hasConcept C2778760513 @default.
• W2912677485 hasConcept C2778979269 @default.
• W2912677485 hasConcept C48349386 @default.
• W2912677485 hasConcept C538909803 @default.

• next